FD&C YELLOW NO. 6

First approved in 1982

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H10N2O7S2.2Na
Molecular Weight	452.369
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[Na+].OC1=CC=C2C=C(C=CC2=C1\N=N\C3=CC=C(C=C3)S([O-])(=O)=O)S([O-])(=O)=O

InChI

InChIKey=OIQPTROHQCGFEF-QIKYXUGXSA-L

InChI=1S/C16H12N2O7S2.2Na/c19-15-8-1-10-9-13(27(23,24)25)6-7-14(10)16(15)18-17-11-2-4-12(5-3-11)26(20,21)22;;/h1-9,19H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2/b18-17+;;

HIDE SMILES / InChI

Description
Sources: https://www.fda.gov/forindustry/coloradditives/coloradditiveinventories/ucm106626.htm | https://sites.google.com/a/umn.edu/phar6157s13/home/d-c-yellow-no-6 | https://www.drugs.com/inactive/d-c-yellow-no-6-343.html

D&C Yellow No. 6 is an excipient (pharmacologically inactive substance). D&C Yellow No. 6 is a color additive. It has been approved for use in food, drugs, and cosmetics. D&C Yellow No. 6 is chemically manufactured by diazotizing 4-aminobenzenesulfonic acid using hydrochloric acid and sodium nitrite or sulfuric acid and sodium nitrite. The diazo compound is coupled with 6-hydroxy-2-naphthalene-sulfonic acid. The dye is isolated as the sodium salt and dried. The trisodium salt of 3-hydroxy-4-[(4-sulfophenyl)azo]-2,7-naphthalenedisulfonic acid which may be blended with the principal color is prepared in the same manner except the diazo benzenesulfonic acid is coupled with 3-hydroxy-2,7-naphthalenedisulfonic acid.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
diaper rash 2 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=dfe6a47c-ec31-4421-877e-f953e4c99889	Inactive ingredient		Approved 8429	JOHNSONS BABY baby shampoos shampoo Approved Use helps treat and prevent diaper rash; protects chafed skin due to diaper rash and helps seal out wetness Launch Date 2012

Sample Use Guides

In Vivo Use Guide

Acceptable daily intake of Yellow No. 6 is 3.75mg/kg/day according to the FDA

Route of Administration: Oral

Name

Type

Language

FD&C YELLOW NO. 6

Common Name

English

YELLOW 6

Official Name

English

CI (1975) NO. 15985

Code

English

SUNSET YELLOW FCF [MART.]

Common Name

English

SUNSET YELLOW FCF [MI]

Common Name

English

E-110

Code

English

SUNSET YELLOW

Official Name

English

SUNSET YELLOW FCF [IARC]

Common Name

English

F D & C YELLOW NO. 6

Common Name

English

CI-FOOD YELLOW 3

Common Name

English

FD&C YELLOW NO. 6 [II]

Common Name

English

F D & C YELLOW #6 ALUMINUM LAKE [VANDF]

Common Name

English

KI5 [INCI]

Common Name

English

INS NO.110

Code

English

FD&C YELLOW NO. 6 [FCC]

Common Name

English

CRELBORANGE S

Common Name

English

KI5	Locators: INCI Naming Organization: INCI Sources:

Official Name

English

INS-110

Code

English

CI 15985 [INCI]

Common Name

English

DISODIUM SALT OF 6-HYDROXY-5-((4-SULFOPHENYL)AZO)-2-NAPHTHALENESULFONIC ACID

Common Name

English

SUNSET YELLOW [FCC]

Common Name

English

F D & C YELLOW #6 [VANDF]

Common Name

English

E110

Code

English

SUNSET YELLOW [INCI]

Common Name

English

COLOUR INDEX NO. 15985

Common Name

English

C.I. FOOD YELLOW 3 [HSDB]

Common Name

English

CI 15985

Official Name

English

FDC YELLOW NO. 6

Common Name

English

FD&C YELLOW 6

Common Name

English

F D & C YELLOW #6 LAKE [VANDF]

Common Name

English

CI-15985

Code

English

SUNSET YELLOW FCF

Common Name

English

YELLOW 6 [INCI]

Common Name

English

CI-(1975)-NO.15985

Code

English

FD&C YELLOW NO.6

Common Name

English

2-NAPHTHALENESULFONIC ACID, 6-HYDROXY-5-((E)-(4-SULFOPHENYL)AZO)-, DISODIUM SALT

Common Name

English

ORANGE YELLOW S

Common Name

English

Classification Tree Code System Code

CODEX ALIMENTARIUS (GSFA)

INS-110