U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C16H10N2O7S2.2Na
Molecular Weight 452.369
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of FD&C YELLOW NO. 6

SMILES

[Na+].[Na+].OC1=CC=C2C=C(C=CC2=C1\N=N\C3=CC=C(C=C3)S([O-])(=O)=O)S([O-])(=O)=O

InChI

InChIKey=OIQPTROHQCGFEF-QIKYXUGXSA-L
InChI=1S/C16H12N2O7S2.2Na/c19-15-8-1-10-9-13(27(23,24)25)6-7-14(10)16(15)18-17-11-2-4-12(5-3-11)26(20,21)22;;/h1-9,19H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2/b18-17+;;

HIDE SMILES / InChI
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C16H10N2O7S2
Molecular Weight 406.39
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Description

D&C Yellow No. 6 is an excipient (pharmacologically inactive substance). D&C Yellow No. 6 is a color additive. It has been approved for use in food, drugs, and cosmetics. D&C Yellow No. 6 is chemically manufactured by diazotizing 4-aminobenzenesulfonic acid using hydrochloric acid and sodium nitrite or sulfuric acid and sodium nitrite. The diazo compound is coupled with 6-hydroxy-2-naphthalene-sulfonic acid. The dye is isolated as the sodium salt and dried. The trisodium salt of 3-hydroxy-4-[(4-sulfophenyl)azo]-2,7-naphthalenedisulfonic acid which may be blended with the principal color is prepared in the same manner except the diazo benzenesulfonic acid is coupled with 3-hydroxy-2,7-naphthalenedisulfonic acid.

Approval Year

1982
100
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
Approved
8429
JOHNSONS BABY baby shampoos shampoo

Approved Use

helps treat and prevent diaper rash; protects chafed skin due to diaper rash and helps seal out wetness

Launch Date

2012

Sample Use Guides

In Vivo Use Guide
Acceptable daily intake of Yellow No. 6 is 3.75mg/kg/day according to the FDA
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:43:52 GMT 2023
Edited
by admin
on Fri Dec 15 15:43:52 GMT 2023
Record UNII
H77VEI93A8
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
FD&C YELLOW NO. 6
FCC   II  
Common Name English
YELLOW 6
INCI  
INCI  
Official Name English
CI (1975) NO. 15985
Code English
SUNSET YELLOW FCF [MART.]
Common Name English
SUNSET YELLOW FCF [MI]
Common Name English
E-110
Code English
SUNSET YELLOW
FCC   INCI  
INCI  
Official Name English
SUNSET YELLOW FCF [IARC]
Common Name English
F D & C YELLOW NO. 6
Common Name English
CI-FOOD YELLOW 3
Common Name English
FD&C YELLOW NO. 6 [II]
Common Name English
F D & C YELLOW #6 ALUMINUM LAKE [VANDF]
Common Name English
KI5 [INCI]
Common Name English
INS NO.110
Code English
FD&C YELLOW NO. 6 [FCC]
Common Name English
CRELBORANGE S
Common Name English
KI5
INCI  
INCI  
Official Name English
INS-110
Code English
CI 15985 [INCI]
Common Name English
DISODIUM SALT OF 6-HYDROXY-5-((4-SULFOPHENYL)AZO)-2-NAPHTHALENESULFONIC ACID
Common Name English
SUNSET YELLOW [FCC]
Common Name English
F D & C YELLOW #6 [VANDF]
Common Name English
E110
Code English
SUNSET YELLOW [INCI]
Common Name English
COLOUR INDEX NO. 15985
Common Name English
C.I. FOOD YELLOW 3 [HSDB]
Common Name English
CI 15985
INCI  
INCI  
Official Name English
FDC YELLOW NO. 6
Common Name English
FD&C YELLOW 6
Common Name English
F D & C YELLOW #6 LAKE [VANDF]
Common Name English
CI-15985
Code English
SUNSET YELLOW FCF
MART.   MI  
Common Name English
YELLOW 6 [INCI]
Common Name English
CI-(1975)-NO.15985
Code English
FD&C YELLOW NO.6
Common Name English
2-NAPHTHALENESULFONIC ACID, 6-HYDROXY-5-((E)-(4-SULFOPHENYL)AZO)-, DISODIUM SALT
Common Name English
ORANGE YELLOW S
Common Name English
Classification Tree Code System Code
CODEX ALIMENTARIUS (GSFA) INS-110
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
NCI_THESAURUS C461
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
CFR 21 CFR 74.706
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
JECFA EVALUATION INS-110
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
Code System Code Type Description
CAS
2783-94-0
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
SMS_ID
100000092524
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
ECHA (EC/EINECS)
220-491-7
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
MESH
C005842
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
EVMPD
SUB26882
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
WIKIPEDIA
SUNSET YELLOW FCF
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
NCI_THESAURUS
C71636
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
FDA UNII
H77VEI93A8
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
MERCK INDEX
m10400
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY Merck Index
DAILYMED
H77VEI93A8
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
RXCUI
1305574
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY RxNorm
Related Record Type Details
D&C YELLOW NO. 6
SUB_CONCEPT->SUBSTANCE
Structure of FOOD YELLOW 3 FREE ACID
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of FOOD YELLOW 3 FREE ACID
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966