U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C16H10N2O7S2.2Na
Molecular Weight 452.369
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of FD&C YELLOW NO. 6

SMILES

[Na+].[Na+].OC1=CC=C2C=C(C=CC2=C1\N=N\C3=CC=C(C=C3)S([O-])(=O)=O)S([O-])(=O)=O

InChI

InChIKey=OIQPTROHQCGFEF-QIKYXUGXSA-L
InChI=1S/C16H12N2O7S2.2Na/c19-15-8-1-10-9-13(27(23,24)25)6-7-14(10)16(15)18-17-11-2-4-12(5-3-11)26(20,21)22;;/h1-9,19H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2/b18-17+;;

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C16H10N2O7S2
Molecular Weight 406.39
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

D&C Yellow No. 6 is an excipient (pharmacologically inactive substance). D&C Yellow No. 6 is a color additive. It has been approved for use in food, drugs, and cosmetics. D&C Yellow No. 6 is chemically manufactured by diazotizing 4-aminobenzenesulfonic acid using hydrochloric acid and sodium nitrite or sulfuric acid and sodium nitrite. The diazo compound is coupled with 6-hydroxy-2-naphthalene-sulfonic acid. The dye is isolated as the sodium salt and dried. The trisodium salt of 3-hydroxy-4-[(4-sulfophenyl)azo]-2,7-naphthalenedisulfonic acid which may be blended with the principal color is prepared in the same manner except the diazo benzenesulfonic acid is coupled with 3-hydroxy-2,7-naphthalenedisulfonic acid.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
JOHNSONS BABY baby shampoos shampoo

Approved Use

helps treat and prevent diaper rash; protects chafed skin due to diaper rash and helps seal out wetness

Launch Date

2012

Sample Use Guides

Acceptable daily intake of Yellow No. 6 is 3.75mg/kg/day according to the FDA
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:43:52 GMT 2023
Edited
by admin
on Fri Dec 15 15:43:52 GMT 2023
Record UNII
H77VEI93A8
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
FD&C YELLOW NO. 6
FCC   II  
Common Name English
YELLOW 6
INCI  
INCI  
Official Name English
CI (1975) NO. 15985
Code English
SUNSET YELLOW FCF [MART.]
Common Name English
SUNSET YELLOW FCF [MI]
Common Name English
E-110
Code English
SUNSET YELLOW
FCC   INCI  
INCI  
Official Name English
SUNSET YELLOW FCF [IARC]
Common Name English
F D & C YELLOW NO. 6
Common Name English
CI-FOOD YELLOW 3
Common Name English
FD&C YELLOW NO. 6 [II]
Common Name English
F D & C YELLOW #6 ALUMINUM LAKE [VANDF]
Common Name English
KI5 [INCI]
Common Name English
INS NO.110
Code English
FD&C YELLOW NO. 6 [FCC]
Common Name English
CRELBORANGE S
Common Name English
KI5
INCI  
INCI  
Official Name English
INS-110
Code English
CI 15985 [INCI]
Common Name English
DISODIUM SALT OF 6-HYDROXY-5-((4-SULFOPHENYL)AZO)-2-NAPHTHALENESULFONIC ACID
Common Name English
SUNSET YELLOW [FCC]
Common Name English
F D & C YELLOW #6 [VANDF]
Common Name English
E110
Code English
SUNSET YELLOW [INCI]
Common Name English
COLOUR INDEX NO. 15985
Common Name English
C.I. FOOD YELLOW 3 [HSDB]
Common Name English
CI 15985
INCI  
INCI  
Official Name English
FDC YELLOW NO. 6
Common Name English
FD&C YELLOW 6
Common Name English
F D & C YELLOW #6 LAKE [VANDF]
Common Name English
CI-15985
Code English
SUNSET YELLOW FCF
MART.   MI  
Common Name English
YELLOW 6 [INCI]
Common Name English
CI-(1975)-NO.15985
Code English
FD&C YELLOW NO.6
Common Name English
2-NAPHTHALENESULFONIC ACID, 6-HYDROXY-5-((E)-(4-SULFOPHENYL)AZO)-, DISODIUM SALT
Common Name English
ORANGE YELLOW S
Common Name English
Classification Tree Code System Code
CODEX ALIMENTARIUS (GSFA) INS-110
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
NCI_THESAURUS C461
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
CFR 21 CFR 74.706
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
JECFA EVALUATION INS-110
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
Code System Code Type Description
CAS
2783-94-0
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
SMS_ID
100000092524
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
ECHA (EC/EINECS)
220-491-7
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
MESH
C005842
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
EVMPD
SUB26882
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
WIKIPEDIA
SUNSET YELLOW FCF
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
NCI_THESAURUS
C71636
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
FDA UNII
H77VEI93A8
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
MERCK INDEX
m10400
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY Merck Index
DAILYMED
H77VEI93A8
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY
RXCUI
1305574
Created by admin on Fri Dec 15 15:43:52 GMT 2023 , Edited by admin on Fri Dec 15 15:43:52 GMT 2023
PRIMARY RxNorm
Related Record Type Details
SUB_CONCEPT->SUBSTANCE
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY