RAMIFENAZONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H19N3O
Molecular Weight	245.3202
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of RAMIFENAZONE

Structure Search

SMILES

CC(C)NC1=C(C)N(C)N(C1=O)C2=CC=CC=C2

InChI

InChIKey=XOZLRRYPUKAKMU-UHFFFAOYSA-N

InChI=1S/C14H19N3O/c1-10(2)15-13-11(3)16(4)17(14(13)18)12-8-6-5-7-9-12/h5-10,15H,1-4H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/21684706 | https://link.springer.com/article/10.1007%2FBF01971489

Ramifenazone is pyrazolone derivative with analgesic, antipyretic, and anti-inflammatory activity. In preclinical studies, Ramifenazone shows potent inhibition of prostaglandin production, carrageenan edema, and yeast fever.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Analysis of three metabolite residues of dipyrone in bovine muscle and pork muscle using high performance liquid chromatography].	2007 Nov	18257301
Analytical strategy for the confirmatory analysis of the non-steroidal anti-inflammatory drugs firocoxib, propyphenazone, ramifenazone and piroxicam in bovine plasma by liquid chromatography tandem mass spectrometry.	2011 Sep 10	21684706

Patents

Patents

Name

Type

Language

RAMIFENAZONE

Official Name

English

ISOPROPYLAMINOPHENAZONE

Systematic Name

English

Ramifenazone [WHO-DD]

Common Name

English

ramifenazone [INN]

Common Name

English

1-PHENYL-2,3-DIMETHYL-4-ISOPROPYLAMINOPYRAZOLONE

Systematic Name

English

NSC-758621

Code

English

RAMIFENAZONE [MART.]

Common Name

English

1-PHENYL-2,3-DIMETHYL-4-(ISOPROPYLAMINO)-2-PYRAZOLIN-5-ONE

Systematic Name

English

ISOPROPYLAMINOANTIPYRINE

Common Name

English

RAMIFENAZONE [MI]

Common Name

English

3H-PYRAZOL-3-ONE, 1,2-DIHYDRO-1,5-DIMETHYL-4-((1-METHYLETHYL)AMINO)-2-PHENYL-

Systematic Name

English

ISOPYRINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

Code System Code Type Description

MESH

C562338

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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NSC

758621

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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INN

5540

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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DRUG CENTRAL

3517

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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EVMPD

SUB10247MIG

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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NCI_THESAURUS

C72125

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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EPA CompTox

DTXSID1045906

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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CAS

3615-24-5

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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SMS_ID

100000080312

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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ECHA (EC/EINECS)

222-791-3

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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PUBCHEM

5037

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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MESH

C017444

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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MERCK INDEX

m9490

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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Merck Index

FDA UNII

GKH2KOV2RF

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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ChEMBL

CHEMBL157337

Created by admin on Fri Dec 15 15:35:31 UTC 2023 , Edited by admin on Fri Dec 15 15:35:31 UTC 2023

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ACTIVE MOIETY


					GKH2KOV2RF

SALT/SOLVATE (PARENT)


					182MZB7ZV8

RAMIFENAZONE HYDROCHLORIDE