PHENOPERIDINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C23H29NO3
Molecular Weight	367.4813
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PHENOPERIDINE

Structure Search

SMILES

CCOC(=O)C1(CCN(CCC(O)C2=CC=CC=C2)CC1)C3=CC=CC=C3

InChI

InChIKey=IPOPQVVNCFQFRK-UHFFFAOYSA-N

InChI=1S/C23H29NO3/c1-2-27-22(26)23(20-11-7-4-8-12-20)14-17-24(18-15-23)16-13-21(25)19-9-5-3-6-10-19/h3-12,21,25H,2,13-18H2,1H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/19186209 | https://www.ncbi.nlm.nih.gov/mesh/68010638 | https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2044.1963.tb13699.x

PHENOPERIDINE is an opioid analgesic partly metabolized to meperidine in the liver. It is derived from pethidine by replacing the N methyl by a phenyl propanol chain. It is reputed to be a typical morphine-like analgesic characterized by its high potency, rapid onset of action, the intensity of its peak effect and the short duration of its pharmacological effects. It is used in general anesthesia.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pain 614 Sources: https://books.google.ru/books?id=o-bzCAAAQBAJ&pg=PA394&lpg=PA394&dq=Operidine retrieved from A Concise Encyclopaedia of Psychiatry: D. Leigh, C.M. Pare, J. Marks, p.394 https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=1308.11	Primary		Approved 8429	Operidine Approved Use A narcotic analgesic

PubMed

PubMed

Title	Date	PubMed
Motor neuropathy associated with cimetidine.	1980 Oct 11	7427548
Contemporary strategies to preserve renal function during cardiac and vascular surgery.	2003	12556734
The consolidation of neuroleptic therapy: Janssen, the discovery of haloperidol and its introduction into clinical practice.	2009 Apr 29	19186209

Patents

Patents

Name

Type

Language

PHENOPERIDINE

Official Name

English

phenoperidine [INN]

Common Name

English

DL-PHENOPERIDINE

Common Name

English

R 1406

Code

English

IDS-NP-010

Code

English

ISONIPECOTIC ACID, 1-(3-HYDROXY-3-PHENYLPROPYL)-4-PHENYL-, ETHYL ESTER

Systematic Name

English

FENOPERIDINA

Common Name

English

PHENOPERIDINE [MI]

Common Name

English

NIH 7591

Code

English

Phenoperidine [WHO-DD]

Common Name

English

FENOPERIDINE

Common Name

English

NIH-7591

Code

English

R-1406

Code

English

1-(3-HYDROXY-3-PHENYLPROPYL)-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

N01AH04

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

WHO-VATC

QN01AH04

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

NCI_THESAURUS

C1506

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

NCI_THESAURUS

C241

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

DEA NO.

9641

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

Code System Code Type Description

NCI_THESAURUS

C72123

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

PRIMARY

DRUG BANK

DB13605

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SMS_ID

100000082259

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ChEMBL

CHEMBL2105385

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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EPA CompTox

DTXSID90862199

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ECHA (EC/EINECS)

209-229-2

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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RXCUI

8143

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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RxNorm

MESH

D010638

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FDA UNII

G9BH09J4JW

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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CAS

562-26-5

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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PUBCHEM

11226

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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WIKIPEDIA

PHENOPERIDINE

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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INN

1062

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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MERCK INDEX

m8632

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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Merck Index

DRUG CENTRAL

3441

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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EVMPD

SUB09775MIG

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

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CAS

66584-15-4

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

SUPERSEDED

CAS

55125-88-7

Created by admin on Sat Dec 16 16:50:46 GMT 2023 , Edited by admin on Sat Dec 16 16:50:46 GMT 2023

SUPERSEDED

ACTIVE MOIETY


					G9BH09J4JW

SALT/SOLVATE (PARENT)


					1D9C1OK7KZ

PHENOPERIDINE HYDROCHLORIDE