PHENOPERIDINE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C23H29NO3.ClH
Molecular Weight	403.942
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PHENOPERIDINE HYDROCHLORIDE

Structure Search

SMILES

Cl.CCOC(=O)C1(CCN(CCC(O)C2=CC=CC=C2)CC1)C3=CC=CC=C3

InChI

InChIKey=HGEAGOBQOIMDQV-UHFFFAOYSA-N

InChI=1S/C23H29NO3.ClH/c1-2-27-22(26)23(20-11-7-4-8-12-20)14-17-24(18-15-23)16-13-21(25)19-9-5-3-6-10-19;/h3-12,21,25H,2,13-18H2,1H3;1H

HIDE SMILES / InChI

Molecular Formula	C23H29NO3
Molecular Weight	367.4813
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/19186209 | https://www.ncbi.nlm.nih.gov/mesh/68010638 | https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2044.1963.tb13699.x

PHENOPERIDINE is an opioid analgesic partly metabolized to meperidine in the liver. It is derived from pethidine by replacing the N methyl by a phenyl propanol chain. It is reputed to be a typical morphine-like analgesic characterized by its high potency, rapid onset of action, the intensity of its peak effect and the short duration of its pharmacological effects. It is used in general anesthesia.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pain 614 Sources: https://books.google.ru/books?id=o-bzCAAAQBAJ&pg=PA394&lpg=PA394&dq=Operidine retrieved from A Concise Encyclopaedia of Psychiatry: D. Leigh, C.M. Pare, J. Marks, p.394 https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=1308.11	Primary		Approved 8429	Operidine Approved Use A narcotic analgesic

PubMed

Title	Date	PubMed
Motor neuropathy associated with cimetidine.	1980 Oct 11	7427548

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:03:47 GMT 2023` Edited by `admin` on `Fri Dec 15 15:03:47 GMT 2023`
Record UNII	1D9C1OK7KZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PHENOPERIDINE HYDROCHLORIDE

Common Name

English

OPERIDINE

Brand Name

English

PHENOPERIDINE HYDROCHLORIDE [MI]

Common Name

English

Phenoperidine hydrochloride [WHO-DD]

Common Name

English

4-PIPERIDINECARBOXYLIC ACID, 1-(3-HYDROXY-3-PHENYLPROPYL)-4-PHENYL-, ETHYL ESTER, HYDROCHLORIDE (1:1)

Common Name

English

ISONIPECOTIC ACID, 1-(3-HYDROXY-3-PHENYLPROPYL)-4-PHENYL-, ETHYL ESTER, HYDROCHLORIDE

Common Name

English

4-PIPERIDINECARBOXYLIC ACID, 1-(3-HYDROXY-3-PHENYLPROPYL)-4-PHENYL-, ETHYL ESTER, HYDROCHLORIDE

Common Name

English

LEALGIN

Brand Name

English

PHENOPERIDINE HCL

Common Name

English

Code System Code Type Description

CHEBI

31984