Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C28H26F4N2OS.C4H4O4 |
| Molecular Weight | 630.65 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)\C=C\C(O)=O.FC1=CC=C(C=C1)C(=O)C2CCN(CCCN3C4=CC(=CC=C4SC5=C3C=CC=C5)C(F)(F)F)CC2
InChI
InChIKey=YETRXLVOWPGIHR-WLHGVMLRSA-N
InChI=1S/C28H26F4N2OS.C4H4O4/c29-22-9-6-19(7-10-22)27(35)20-12-16-33(17-13-20)14-3-15-34-23-4-1-2-5-25(23)36-26-11-8-21(18-24(26)34)28(30,31)32;5-3(6)1-2-4(7)8/h1-2,4-11,18,20H,3,12-17H2;1-2H,(H,5,6)(H,7,8)/b;2-1+
Duoperone is a neuroleptic agent. Duoperone blocked d-amphetamine lethality in mice under aggregated conditions when the pretreatment interval was between one hour and seven days. Conditioned avoidance responding in mice and cats was suppressed by duoperone in doses that did not impair escape behavior. Duoperone produced catalepsy in rats. The onset of this effect was delayed and the duration was prolonged when compared with that of chlorpromazine. It was a potent antiemetic agent in dogs, with a delayed onset and prolonged duration of action.
Approval Year
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NCI_THESAURUS |
C29710
Created by
admin on Mon Mar 31 17:57:51 GMT 2025 , Edited by admin on Mon Mar 31 17:57:51 GMT 2025
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CHEMBL2110736
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C74170
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G7MM186D7U
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12404417
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62030-89-1
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W-86
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300000055441
Created by
admin on Mon Mar 31 17:57:51 GMT 2025 , Edited by admin on Mon Mar 31 17:57:51 GMT 2025
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PRIMARY |
ACTIVE MOIETY
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD
