Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C28H26F4N2OS |
| Molecular Weight | 514.577 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
FC1=CC=C(C=C1)C(=O)C2CCN(CCCN3C4=CC=CC=C4SC5=CC=C(C=C35)C(F)(F)F)CC2
InChI
InChIKey=XMUZRUCADGTCPX-UHFFFAOYSA-N
InChI=1S/C28H26F4N2OS/c29-22-9-6-19(7-10-22)27(35)20-12-16-33(17-13-20)14-3-15-34-23-4-1-2-5-25(23)36-26-11-8-21(18-24(26)34)28(30,31)32/h1-2,4-11,18,20H,3,12-17H2
| Molecular Formula | C28H26F4N2OS |
| Molecular Weight | 514.577 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Duoperone is a neuroleptic agent. Duoperone blocked d-amphetamine lethality in mice under aggregated conditions when the pretreatment interval was between one hour and seven days. Conditioned avoidance responding in mice and cats was suppressed by duoperone in doses that did not impair escape behavior. Duoperone produced catalepsy in rats. The onset of this effect was delayed and the duration was prolonged when compared with that of chlorpromazine. It was a potent antiemetic agent in dogs, with a delayed onset and prolonged duration of action.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 17:52:32 UTC 2023
by
admin
on
Sat Dec 16 17:52:32 UTC 2023
|
| Record UNII |
E84FJ4KW3B
|
| Record Status |
Validated (UNII)
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| Record Version |
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| Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C740
Created by
admin on Sat Dec 16 17:52:32 UTC 2023 , Edited by admin on Sat Dec 16 17:52:32 UTC 2023
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NCI_THESAURUS |
C29710
Created by
admin on Sat Dec 16 17:52:32 UTC 2023 , Edited by admin on Sat Dec 16 17:52:32 UTC 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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CHEMBL2110736
Created by
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PRIMARY | |||
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C054030
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E84FJ4KW3B
Created by
admin on Sat Dec 16 17:52:32 UTC 2023 , Edited by admin on Sat Dec 16 17:52:32 UTC 2023
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100000080498
Created by
admin on Sat Dec 16 17:52:32 UTC 2023 , Edited by admin on Sat Dec 16 17:52:32 UTC 2023
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C65499
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62030-88-0
Created by
admin on Sat Dec 16 17:52:32 UTC 2023 , Edited by admin on Sat Dec 16 17:52:32 UTC 2023
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43876
Created by
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DTXSID20866903
Created by
admin on Sat Dec 16 17:52:32 UTC 2023 , Edited by admin on Sat Dec 16 17:52:32 UTC 2023
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PRIMARY | |||
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SUB06428MIG
Created by
admin on Sat Dec 16 17:52:32 UTC 2023 , Edited by admin on Sat Dec 16 17:52:32 UTC 2023
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PRIMARY | |||
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5828
Created by
admin on Sat Dec 16 17:52:32 UTC 2023 , Edited by admin on Sat Dec 16 17:52:32 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
