Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H29N4O11.Na |
| Molecular Weight | 500.4328 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].C[C@H](NC(=O)CO[C@@H]([C@H](O)[C@H](O)CO)[C@@H](NC(C)=O)C=O)C(=O)N[C@H](CCC([O-])=O)C(N)=O
InChI
InChIKey=LWDLWMRHPMEHTA-FRSJEOSWSA-M
InChI=1S/C18H30N4O11.Na/c1-8(18(32)22-10(17(19)31)3-4-14(28)29)20-13(27)7-33-16(15(30)12(26)6-24)11(5-23)21-9(2)25;/h5,8,10-12,15-16,24,26,30H,3-4,6-7H2,1-2H3,(H2,19,31)(H,20,27)(H,21,25)(H,22,32)(H,28,29);/q;+1/p-1/t8-,10+,11-,12+,15+,16+;/m0./s1
Almurtide (CGP 11637) is a synthetic muramyl dipeptide (MDP) analogue with potential immunostimulating and antineoplastic activity. As a derivative of the mycobacterial cell wall component MDP, almurtide activates both monocytes and macrophages. This results in the secretion of cytokines and induces the recruitment and activation of other immune cells, which may result in indirect tumoricidal or cytostatic effects. CGP 11637 has been shown to prevent oncogenic viral infections in mice.
Approval Year
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103882-13-9
Created by
admin on Tue Apr 01 17:29:10 GMT 2025 , Edited by admin on Tue Apr 01 17:29:10 GMT 2025
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G09BIN46IX
Created by
admin on Tue Apr 01 17:29:10 GMT 2025 , Edited by admin on Tue Apr 01 17:29:10 GMT 2025
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121596538
Created by
admin on Tue Apr 01 17:29:10 GMT 2025 , Edited by admin on Tue Apr 01 17:29:10 GMT 2025
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PRIMARY |
ACTIVE MOIETY
SUBSTANCE RECORD
