Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H29N4O11.Na |
| Molecular Weight | 500.4328 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].C[C@H](NC(=O)CO[C@@H]([C@H](O)[C@H](O)CO)[C@@H](NC(C)=O)C=O)C(=O)N[C@H](CCC([O-])=O)C(N)=O
InChI
InChIKey=LWDLWMRHPMEHTA-FRSJEOSWSA-M
InChI=1S/C18H30N4O11.Na/c1-8(18(32)22-10(17(19)31)3-4-14(28)29)20-13(27)7-33-16(15(30)12(26)6-24)11(5-23)21-9(2)25;/h5,8,10-12,15-16,24,26,30H,3-4,6-7H2,1-2H3,(H2,19,31)(H,20,27)(H,21,25)(H,22,32)(H,28,29);/q;+1/p-1/t8-,10+,11-,12+,15+,16+;/m0./s1
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C18H29N4O11 |
| Molecular Weight | 477.4431 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Almurtide (CGP 11637) is a synthetic muramyl dipeptide (MDP) analogue with potential immunostimulating and antineoplastic activity. As a derivative of the mycobacterial cell wall component MDP, almurtide activates both monocytes and macrophages. This results in the secretion of cytokines and induces the recruitment and activation of other immune cells, which may result in indirect tumoricidal or cytostatic effects. CGP 11637 has been shown to prevent oncogenic viral infections in mice.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 11:55:28 GMT 2023
by
admin
on
Sat Dec 16 11:55:28 GMT 2023
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| Record UNII |
G09BIN46IX
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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Systematic Name | English |
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103882-13-9
Created by
admin on Sat Dec 16 11:55:28 GMT 2023 , Edited by admin on Sat Dec 16 11:55:28 GMT 2023
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G09BIN46IX
Created by
admin on Sat Dec 16 11:55:28 GMT 2023 , Edited by admin on Sat Dec 16 11:55:28 GMT 2023
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PRIMARY | |||
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121596538
Created by
admin on Sat Dec 16 11:55:28 GMT 2023 , Edited by admin on Sat Dec 16 11:55:28 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |