Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H30N4O11 |
| Molecular Weight | 478.451 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@H](NC(=O)CO[C@@H]([C@H](O)[C@H](O)CO)[C@@H](NC(C)=O)C=O)C(=O)N[C@H](CCC(O)=O)C(N)=O
InChI
InChIKey=NWMHDZMRVUOQGL-CZEIJOLGSA-N
InChI=1S/C18H30N4O11/c1-8(18(32)22-10(17(19)31)3-4-14(28)29)20-13(27)7-33-16(15(30)12(26)6-24)11(5-23)21-9(2)25/h5,8,10-12,15-16,24,26,30H,3-4,6-7H2,1-2H3,(H2,19,31)(H,20,27)(H,21,25)(H,22,32)(H,28,29)/t8-,10+,11-,12+,15+,16+/m0/s1
| Molecular Formula | C18H30N4O11 |
| Molecular Weight | 478.451 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Almurtide (CGP 11637) is a synthetic muramyl dipeptide (MDP) analogue with potential immunostimulating and antineoplastic activity. As a derivative of the mycobacterial cell wall component MDP, almurtide activates both monocytes and macrophages. This results in the secretion of cytokines and induces the recruitment and activation of other immune cells, which may result in indirect tumoricidal or cytostatic effects. CGP 11637 has been shown to prevent oncogenic viral infections in mice.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:05:44 GMT 2023
by
admin
on
Fri Dec 15 16:05:44 GMT 2023
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| Record UNII |
1DCO35D4OR
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C129820
Created by
admin on Fri Dec 15 16:05:44 GMT 2023 , Edited by admin on Fri Dec 15 16:05:44 GMT 2023
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| Code System | Code | Type | Description | ||
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7450
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124876
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CHEMBL2106040
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admin on Fri Dec 15 16:05:44 GMT 2023 , Edited by admin on Fri Dec 15 16:05:44 GMT 2023
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100000087463
Created by
admin on Fri Dec 15 16:05:44 GMT 2023 , Edited by admin on Fri Dec 15 16:05:44 GMT 2023
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SUB05352MIG
Created by
admin on Fri Dec 15 16:05:44 GMT 2023 , Edited by admin on Fri Dec 15 16:05:44 GMT 2023
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61136-12-7
Created by
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DTXSID40210025
Created by
admin on Fri Dec 15 16:05:44 GMT 2023 , Edited by admin on Fri Dec 15 16:05:44 GMT 2023
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1DCO35D4OR
Created by
admin on Fri Dec 15 16:05:44 GMT 2023 , Edited by admin on Fri Dec 15 16:05:44 GMT 2023
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C81667
Created by
admin on Fri Dec 15 16:05:44 GMT 2023 , Edited by admin on Fri Dec 15 16:05:44 GMT 2023
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PRIMARY |
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SALT/SOLVATE -> PARENT |
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PARENT -> DERIVATIVE |
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ACTIVE MOIETY |
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