Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C15H11I2O3.Na |
| Molecular Weight | 516.0447 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].OC1=C(I)C=C(CC(C([O-])=O)C2=CC=CC=C2)C=C1I
InChI
InChIKey=JFFBJAOFKRCWPX-UHFFFAOYSA-M
InChI=1S/C15H12I2O3.Na/c16-12-7-9(8-13(17)14(12)18)6-11(15(19)20)10-4-2-1-3-5-10;/h1-5,7-8,11,18H,6H2,(H,19,20);/q;+1/p-1
Iodoalphionic acid is the contrast medium, which was used for gallbladder examination. It is rarely appeared in the colon and, therefore, rarely masked the gallbladder. The density of the shadow produced by Iodoalphionic acid was greater than that produced by iodophthalein. It was reliable peroral cholecystographic medium, which was less objectionable to take and seldom causes vomiting. Diarrhoea occurred in some cases, but not more often than with tetraiodophenolphthalein. The ingestion of Iodoalphionic acid resulted in low thyroidal radioiodine accumulation for periods ranging from a few weeks to many months.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pheniodol: A Contrast Medium for Cholecystography. | 1943 Nov 27 |
|
| Pheniodol, a new dye for cholecystography. | 1946 Feb |
|
| Some experiences with priodax. | 1946 Jun |
|
| The compatibility of castor oil and priodax in concurrent examination of the colon and gallbladder. | 1949 Jul |
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| Priodax and pseudoalbuminuria. | 1950 Nov |
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| Absorption and excretion of pheniodol labelled with radioactive iodine. | 1951 Apr |
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| Absorption and excretion of pheniodol. | 1951 Jul 21 |
|
| Comparison of cholecystography with iodoalphionic acid (priodax) and a new gallbladder dye, iodopropanoic acid (telepaque). | 1952 Aug |
|
| [Inefficacy of iodoalphionic acid in radical cure of taeniasis]. | 1952 Nov-Dec |
|
| Pseudo-albuminuria following monophen and priodax. | 1952 Sep |
|
| [Comparative cholecystographic study of iodopanoic acid (telepaque) and iodoalphionic acid]. | 1953 |
|
| A comparative clinical study of priodax and telepague, including 1,000 examinations. | 1953 Feb |
|
| [Comparative study of iodopanoic acid (telepaque) and iodoalphionic acid (pheniodol) in cholecystography; densitometric and plainimetric x-ray study of 100 cases]. | 1954 |
|
| [Duodenal intubation of acranil and iodoalphionic acid in therapy of teniasis]. | 1954 Jan-Mar |
|
| Cholegraphy; the new contrast medium biligrafin. | 1955 May |
|
| Influence of iodoalphionic acid priodax, with and without thyrotropin, on thyroidal I 131 uptake in euthyroid patients. | 1957 Jan |
|
| Effects of an organic iodine compound priodax on tests of thyroid function. | 1957 Jan |
|
| [A new mercurometric determination of pheniodol (Coletrast)]. | 1967 Aug |
|
| Unaltered bromsulphalein retention following cholecystography. | 1968 Oct |
|
| [Effect of contrast agents on the iodine-absorbing function of the thyroid gland]. | 1982 Mar-Apr |
|
| [Effect of tri-iodine-containing x-ray contrast substances on the blood coagulation system in an experiment]. | 1984 Jul-Aug |
|
| [Competitive interrelations between bilirubin and x-ray contrast agents in binding with human serum albumin]. | 1986 Mar-Apr |
|
| Non-peptidic small-molecule inhibitors of the single-chain hepatitis C virus NS3 protease/NS4A cofactor complex discovered by structure-based NMR screening. | 2004 May 6 |
Patents
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CHEMBL83906
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3303
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C175842
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23665871
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D3N32O7NLB
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100000082236
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SUB09766MIG
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230-288-5
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4171
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7009-60-1
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PARENT (SALT/SOLVATE)
SUBSTANCE RECORD
