Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C15H12I2O3 |
| Molecular Weight | 494.0629 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
| Stereo Comments | DL-IODOALPHIONIC ACID |
SHOW SMILES / InChI
SMILES
OC(=O)C(CC1=CC(I)=C(O)C(I)=C1)C2=CC=CC=C2
InChI
InChIKey=IKYIXZSIKOYSLD-UHFFFAOYSA-N
InChI=1S/C15H12I2O3/c16-12-7-9(8-13(17)14(12)18)6-11(15(19)20)10-4-2-1-3-5-10/h1-5,7-8,11,18H,6H2,(H,19,20)
| Molecular Formula | C15H12I2O3 |
| Molecular Weight | 494.0629 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Iodoalphionic acid is the contrast medium, which was used for gallbladder examination. It is rarely appeared in the colon and, therefore, rarely masked the gallbladder. The density of the shadow produced by Iodoalphionic acid was greater than that produced by iodophthalein. It was reliable peroral cholecystographic medium, which was less objectionable to take and seldom causes vomiting. Diarrhoea occurred in some cases, but not more often than with tetraiodophenolphthalein. The ingestion of Iodoalphionic acid resulted in low thyroidal radioiodine accumulation for periods ranging from a few weeks to many months.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pheniodol: A Contrast Medium for Cholecystography. | 1943 Nov 27 |
|
| Pheniodol, a new dye for cholecystography. | 1946 Feb |
|
| Some experiences with priodax. | 1946 Jun |
|
| The compatibility of castor oil and priodax in concurrent examination of the colon and gallbladder. | 1949 Jul |
|
| [Inefficacy of iodoalphionic acid in radical cure of taeniasis]. | 1952 Nov-Dec |
|
| [Comparative cholecystographic study of iodopanoic acid (telepaque) and iodoalphionic acid]. | 1953 |
|
| [Comparative study of iodopanoic acid (telepaque) and iodoalphionic acid (pheniodol) in cholecystography; densitometric and plainimetric x-ray study of 100 cases]. | 1954 |
|
| [Duodenal intubation of acranil and iodoalphionic acid in therapy of teniasis]. | 1954 Jan-Mar |
|
| Cholegraphy; the new contrast medium biligrafin. | 1955 May |
|
| Effects of an organic iodine compound priodax on tests of thyroid function. | 1957 Jan |
|
| [A new mercurometric determination of pheniodol (Coletrast)]. | 1967 Aug |
|
| Unaltered bromsulphalein retention following cholecystography. | 1968 Oct |
|
| [Effect of contrast agents on the iodine-absorbing function of the thyroid gland]. | 1982 Mar-Apr |
|
| [Effect of tri-iodine-containing x-ray contrast substances on the blood coagulation system in an experiment]. | 1984 Jul-Aug |
|
| [Competitive interrelations between bilirubin and x-ray contrast agents in binding with human serum albumin]. | 1986 Mar-Apr |
|
| Non-peptidic small-molecule inhibitors of the single-chain hepatitis C virus NS3 protease/NS4A cofactor complex discovered by structure-based NMR screening. | 2004 May 6 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:15:54 GMT 2023
by
admin
on
Fri Dec 15 16:15:54 GMT 2023
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| Record UNII |
060B6580LL
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| Record Status |
Validated (UNII)
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| Record Version |
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NCI_THESAURUS |
C28500
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577-91-3
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C75626
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11350
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209-417-4
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CHEMBL83906
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404169
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DTXSID6046131
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m6339
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11854
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ACTIVE MOIETY |
