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Details

Stereochemistry ACHIRAL
Molecular Formula CCl4
Molecular Weight 153.823
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Carbon tetrachloride

SMILES

ClC(Cl)(Cl)Cl

InChI

InChIKey=VZGDMQKNWNREIO-UHFFFAOYSA-N
InChI=1S/CCl4/c2-1(3,4)5

HIDE SMILES / InChI
Carbon tetrachloride, also called tetrachloromethane, a colourless, dense, highly toxic, volatile, nonflammable liquid possessing a characteristic odour and belonging to the family of organic halogen compounds, used principally in the manufacture of dichlorodifluoromethane. Carbon tetrachloride is commonly used as a chemical intermediate, solvent, and dry-cleaning fluid. It was widely used as a cleaning fluid. Carbon tetrachloride was also used in fire extinguishers and as a fumigant to kill insects in grain. Human exposure to carbon tetrachloride from occupational or environmental sources is low and unlikely to produce acute kidney toxicity. Carbon tetrachloride is a manufactured chemical and does not occur naturally in the environment.

Approval Year

PubMed

PubMed

TitleDatePubMed
Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL.
2001-07-13
Investigation of cell exudates active in carbon tetrachloride and chloroform degradation.
2001-07-05
Hepatoprotective activity of Luffa echinata fruits.
2001-07
JunD regulates transcription of the tissue inhibitor of metalloproteinases-1 and interleukin-6 genes in activated hepatic stellate cells.
2001-06-29
Time-resolved total internal reflection fluorometry study on polarity at a liquid/liquid interface.
2001-06-01
Kinetics and mechanisms of hepatic acute phase response to subtotal partial hepatectomy and cultural impact on environmental hepatic end-stage liver injury in the homeless.
2001-06
Earlier expression of the transcription factor HFH-11B diminishes induction of p21(CIP1/WAF1) levels and accelerates mouse hepatocyte entry into S-phase following carbon tetrachloride liver injury.
2001-06
Influence of ferrous iron and ph on carbon tetrachloride degradation by Methanosarcina thermophila.
2001-06
Unique gene expression patterns in liver and kidney associated with exposure to chemical toxicants.
2001-06
Hepatocyte growth factor promotes liver regeneration and protein synthesis after hepatectomy in cirrhotic rats.
2001-05-31
Hepatocyte damage induced by carbon tetrachloride: inhibited lipoprotein secretion and changed lipoprotein composition.
2001-05-24
Radiolytic and thermal dechlorination of organic chlorides adsorbed on molecular sieve 13X.
2001-05-15
Visualization of solute migration in chromatographic columns influence of the frit porosity.
2001-05-11
Noninvasive determination of the location and distribution of DNAPL using advanced seismic reflection techniques.
2001-05-09
Risk of pancreatic cancer in workers exposed to chlorinated hydrocarbon solvents and related compounds: a meta-analysis.
2001-05-01
Rhamnazin-4'-O-beta-[apiosyl(1-->2)] glucoside as a means of antioxidative defense against tetrachloromethane induced hepatotoxicity in rats.
2001-05
The influence of chlorine on the intensity of metal atomic lines emitted by an electrolyte cathode atmospheric glow discharge.
2001-05
Determination of elemental sulfur in coal by gas chromatography-mass spectrometry.
2001-05
Transplantation of cultured allogeneic hepatocytes without immunosuppression.
2001-05
Optimization of an exogenous metabolic activation system for FETAX. II. Preliminary evaluation.
2001-05
Effects of dietary curcumin on glutathione S-transferase and malondialdehyde-DNA adducts in rat liver and colon mucosa: relationship with drug levels.
2001-05
RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays.
2001-05
Liver-type arginase is a highly sensitive marker for hepatocellular damage in rats.
2001-05
Role of nitric oxide (NO) in pulmonary dysfunction associated with experimental cirrhosis.
2001-05
Analysis of C2-C4 peroxyacyl nitrates and C1-C5 alkyl nitrates with a non-polar capillary column.
2001-04-27
Pathogenesis of carbon tetrachloride-induced hepatocyte injury bioactivation of CCI4 by cytochrome P450 and effects on lipid homeostasis.
2001-04-17
Prooxidant and antioxidant functions of nitric oxide in liver toxicity.
2001-04
Increase of tissue lipid hydroperoxides as determination of oxidative stress.
2001-04
Glycogen-forming function of hepatocytes in cirrhotically altered rat liver after treatment with chorionic gonadotropin.
2001-04
Carbon tetrachloride-induced acute liver injury in Mini and Wistar rats.
2001-04
Protective effects of acetylbergenin against carbon tetrachloride-induced hepatotoxicity in rats.
2001-04
Reduction of carbon tetrachloride-induced rat liver injury by IRFI 042, a novel dual vitamin E-like antioxidant.
2001-04
Enhanced expression of endothelin receptor subtypes in cirrhotic rat liver.
2001-04
Regulation of cholangiocyte proliferation.
2001-04
Measurement of volatile organic compounds in sediments of the Scheldt estuary and the Southern North Sea.
2001-04
Role of inflammation in chemical-induced hepatotoxicity.
2001-03-31
Role of cytokines in non-genotoxic hepatocarcinogenesis: cause or effect?
2001-03-31
The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis.
2001-03-31
Apoptosis in dissociation between DNA synthesis and cellular functions of activated hepatic stellate cells--a study with carbon tetrachloride-induced rat liver injury.
2001-03-30
Visible light-induced degradation of carbon tetrachloride on dye-sensitized TiO2.
2001-03-01
5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication.
2001-03
Efficiency of rice bran for removal of organochlorine compounds and benzene from industrial wastewater.
2001-03
Transformation of chlorinated aliphatic compounds by ferruginous smectite.
2001-02-15
Evaluation of oxidative stress during apoptosis and necrosis caused by carbon tetrachloride in rat liver.
2001-02-14
Carbon tetrachloride dechlorination by the bacterial transition metal chelator pyridine-2,6-bis(thiocarboxylic acid).
2001-02-01
The role of antioxidant vitamins (C and E), selenium and Nigella sativa in the prevention of liver fibrosis and cirrhosis in rabbits: new hopes.
2001-02
Vitamin E reduces lipid peroxidation in experimental hepatotoxicity in rats.
2001-02
Fructose, 1,6-diphosphate mitigates CCl4 suppressed nitric oxide synthase activity in rats.
2001-01
Interaction between monensin and CCl4 after chronic treatment: dolichol and retinol content of rat liver sinusoidal cells.
2001
Applications of microarray technology in breast cancer research.
2001
Patents
Name Type Language
Carbon tetrachloride
HSDB   ISO   MART.   MI   WHO-DD  
Systematic Name English
CARBONEUM CHLORATUM
HPUS  
Preferred Name English
CARBONEUM CHLORATUM [HPUS]
Common Name English
CARBON TETRACHLORIDE [IARC]
Common Name English
CARBON TETRACHLORIDE [MI]
Common Name English
METHANE, TETRACHLORO-
Systematic Name English
CARBON TETRACHLORIDE [USP-RS]
Common Name English
CARBON TETRACHLORIDE [MART.]
Common Name English
Carbon tetrachloride [WHO-DD]
Common Name English
CARBON TETRACHLORIDE [ISO]
Common Name English
CARBON TETRACHLORIDE [HSDB]
Common Name English
NSC-97063
Code English
Classification Tree Code System Code
IARC Carbon tetrachloride
EPA PESTICIDE CODE 16501
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
NCI_THESAURUS C45386
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
Code System Code Type Description
FDA UNII
CL2T97X0V0
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PRIMARY
MESH
D002251
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PRIMARY
RXCUI
2383337
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PRIMARY
CAS
56-23-5
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PRIMARY
DAILYMED
CL2T97X0V0
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PRIMARY
ALANWOOD
carbon tetrachloride
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PRIMARY
SMS_ID
300000053205
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PRIMARY
HSDB
52
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PRIMARY
ChEMBL
CHEMBL44814
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PRIMARY
DRUG CENTRAL
3067
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PRIMARY
RS_ITEM_NUM
1601168
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PRIMARY
WIKIPEDIA
CARBON TETRACHLORIDE
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PRIMARY
EPA CompTox
DTXSID8020250
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PRIMARY
PUBCHEM
5943
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ECHA (EC/EINECS)
200-262-8
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PRIMARY
NSC
97063
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
CHEBI
27385
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
NCI_THESAURUS
C44350
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
MERCK INDEX
m3086
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PRIMARY Merck Index