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Details

Stereochemistry ACHIRAL
Molecular Formula CCl4
Molecular Weight 153.823
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Carbon tetrachloride

SMILES

ClC(Cl)(Cl)Cl

InChI

InChIKey=VZGDMQKNWNREIO-UHFFFAOYSA-N
InChI=1S/CCl4/c2-1(3,4)5

HIDE SMILES / InChI

Molecular Formula CCl4
Molecular Weight 153.823
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Carbon tetrachloride, also called tetrachloromethane, a colourless, dense, highly toxic, volatile, nonflammable liquid possessing a characteristic odour and belonging to the family of organic halogen compounds, used principally in the manufacture of dichlorodifluoromethane. Carbon tetrachloride is commonly used as a chemical intermediate, solvent, and dry-cleaning fluid. It was widely used as a cleaning fluid. Carbon tetrachloride was also used in fire extinguishers and as a fumigant to kill insects in grain. Human exposure to carbon tetrachloride from occupational or environmental sources is low and unlikely to produce acute kidney toxicity. Carbon tetrachloride is a manufactured chemical and does not occur naturally in the environment.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Cytoplasmic crystals (cholesterol?) in acute and chronic liver lesions. Electron microscopic study].
1976 Oct
Inhibition of cytochrome P450 2E1 expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury.
1999 Apr 12
Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase.
2000 Aug
Increase of tissue lipid hydroperoxides as determination of oxidative stress.
2001 Apr
Protective effects of acetylbergenin against carbon tetrachloride-induced hepatotoxicity in rats.
2001 Apr
Reduction of carbon tetrachloride-induced rat liver injury by IRFI 042, a novel dual vitamin E-like antioxidant.
2001 Apr
Distinct roles of tumor necrosis factor-alpha and nitric oxide in acute liver injury induced by carbon tetrachloride in mice.
2001 Apr 1
Analysis of C2-C4 peroxyacyl nitrates and C1-C5 alkyl nitrates with a non-polar capillary column.
2001 Apr 27
Anti-fibrotic effects of a hot-water extract from Salvia miltiorrhiza roots on liver fibrosis induced by biliary obstruction in rats.
2001 Feb
Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: effects of different cytotoxins on cytochrome P450 mediated monooxygenase functions and on oxidative state.
2001 Feb
Cleanup worker exposures to hazardous chemicals at a former nuclear weapons plant: piloting of an exposure surveillance system.
2001 Feb
Eigenvalues and principal component loadings of heavily overlapped vibrational spectra.
2001 Feb
Charge-transfer complex formation between o-chloranil and a series of polynuclear aromatic hydrocarbons.
2001 Feb
Evaluation of oxidative stress during apoptosis and necrosis caused by carbon tetrachloride in rat liver.
2001 Feb 14
Transformation of chlorinated aliphatic compounds by ferruginous smectite.
2001 Feb 15
A novel role of complement: mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration.
2001 Feb 15
Simultaneous induction of galectin-3 phosphorylated on tyrosine residue, p21(WAF1/Cip1/Sdi1), and the proliferating cell nuclear antigen at a distinctive period of repair of hepatocytes injured by CCl4.
2001 Feb 2
Pyriform cortex beta-waves: odor-specific sensitization following repeated olfactory stimulation.
2001 Feb 23
Fructose, 1,6-diphosphate mitigates CCl4 suppressed nitric oxide synthase activity in rats.
2001 Jan
Expression patterns of cell cycle-related proteins in a rat cirrhotic model induced by CCl4 or thioacetamide.
2001 Jan
Near infrared spectra (4000-10 500 cm-1) of phenol-OH and phenol-OD in carbon tetrachloride.
2001 Jan
Potential transition state phosphoramidate inhibitors of beta-tubulin as antifilarial agents.
2001 Jan
Simple time weighted average level air-monitoring method for sulfur mustard in work places.
2001 Jan 12
Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL.
2001 Jul 13
Influence of ferrous iron and ph on carbon tetrachloride degradation by Methanosarcina thermophila.
2001 Jun
Time-resolved total internal reflection fluorometry study on polarity at a liquid/liquid interface.
2001 Jun 1
JunD regulates transcription of the tissue inhibitor of metalloproteinases-1 and interleukin-6 genes in activated hepatic stellate cells.
2001 Jun 29
5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication.
2001 Mar
Uptake, tissue distribution, and fate of inhaled carbon tetrachloride: comparison of rat, mouse, and hamster.
2001 Mar
Heterogeneity and plasticity of hepatocyte lineage cells.
2001 Mar
Induction of metallothionein in the liver of carbon tetrachloride intoxicated rats: an immunohistochemical study.
2001 Mar 21
Apoptosis in dissociation between DNA synthesis and cellular functions of activated hepatic stellate cells--a study with carbon tetrachloride-induced rat liver injury.
2001 Mar 30
Role of inflammation in chemical-induced hepatotoxicity.
2001 Mar 31
The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis.
2001 Mar 31
RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays.
2001 May
Liver-type arginase is a highly sensitive marker for hepatocellular damage in rats.
2001 May
Risk of pancreatic cancer in workers exposed to chlorinated hydrocarbon solvents and related compounds: a meta-analysis.
2001 May 1
Visualization of solute migration in chromatographic columns influence of the frit porosity.
2001 May 11
Radiolytic and thermal dechlorination of organic chlorides adsorbed on molecular sieve 13X.
2001 May 15
Noninvasive determination of the location and distribution of DNAPL using advanced seismic reflection techniques.
2001 May-Jun
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:32:11 GMT 2025
Edited
by admin
on Mon Mar 31 18:32:11 GMT 2025
Record UNII
CL2T97X0V0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Carbon tetrachloride
HSDB   ISO   MART.   MI   WHO-DD  
Systematic Name English
CARBONEUM CHLORATUM
HPUS  
Preferred Name English
CARBONEUM CHLORATUM [HPUS]
Common Name English
CARBON TETRACHLORIDE [IARC]
Common Name English
CARBON TETRACHLORIDE [MI]
Common Name English
METHANE, TETRACHLORO-
Systematic Name English
CARBON TETRACHLORIDE [USP-RS]
Common Name English
CARBON TETRACHLORIDE [MART.]
Common Name English
Carbon tetrachloride [WHO-DD]
Common Name English
CARBON TETRACHLORIDE [ISO]
Common Name English
CARBON TETRACHLORIDE [HSDB]
Common Name English
NSC-97063
Code English
Classification Tree Code System Code
IARC Carbon tetrachloride
EPA PESTICIDE CODE 16501
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
NCI_THESAURUS C45386
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
Code System Code Type Description
FDA UNII
CL2T97X0V0
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
MESH
D002251
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
RXCUI
2383337
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
CAS
56-23-5
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
DAILYMED
CL2T97X0V0
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
ALANWOOD
carbon tetrachloride
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
SMS_ID
300000053205
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
HSDB
52
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
ChEMBL
CHEMBL44814
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
DRUG CENTRAL
3067
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
RS_ITEM_NUM
1601168
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
WIKIPEDIA
CARBON TETRACHLORIDE
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
EPA CompTox
DTXSID8020250
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
PUBCHEM
5943
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
ECHA (EC/EINECS)
200-262-8
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
NSC
97063
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
CHEBI
27385
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
NCI_THESAURUS
C44350
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY
MERCK INDEX
m3086
Created by admin on Mon Mar 31 18:32:11 GMT 2025 , Edited by admin on Mon Mar 31 18:32:11 GMT 2025
PRIMARY Merck Index