Details
Stereochemistry | ACHIRAL |
Molecular Formula | CCl4 |
Molecular Weight | 153.823 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC(Cl)(Cl)Cl
InChI
InChIKey=VZGDMQKNWNREIO-UHFFFAOYSA-N
InChI=1S/CCl4/c2-1(3,4)5
Molecular Formula | CCl4 |
Molecular Weight | 153.823 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Carbon tetrachloride, also called tetrachloromethane, a colourless, dense, highly toxic, volatile, nonflammable liquid possessing a characteristic odour and belonging to the family of organic halogen compounds, used principally in the manufacture of dichlorodifluoromethane. Carbon tetrachloride is commonly used as a chemical intermediate, solvent, and dry-cleaning fluid. It was widely used as a cleaning fluid. Carbon tetrachloride was also used in fire extinguishers and as a fumigant to kill insects in grain. Human exposure to carbon tetrachloride from occupational or environmental sources is low and unlikely to produce acute kidney toxicity. Carbon tetrachloride is a manufactured chemical and does not occur naturally in the environment.
Approval Year
PubMed
Title | Date | PubMed |
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Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: effects of various mitogens and cytotoxins on cytochrome P450 (P450) isoforms expression and on P450 mediated monooxygenase functions. | 1999 Jul |
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Interaction between monensin and CCl4 after chronic treatment: dolichol and retinol content of rat liver sinusoidal cells. | 2001 |
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Applications of microarray technology in breast cancer research. | 2001 |
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Prooxidant and antioxidant functions of nitric oxide in liver toxicity. | 2001 Apr |
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Measurement of volatile organic compounds in sediments of the Scheldt estuary and the Southern North Sea. | 2001 Apr |
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Normal liver regeneration in p50/nuclear factor kappaB1 knockout mice. | 2001 Apr |
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The role of antioxidant vitamins (C and E), selenium and Nigella sativa in the prevention of liver fibrosis and cirrhosis in rabbits: new hopes. | 2001 Feb |
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Vitamin E reduces lipid peroxidation in experimental hepatotoxicity in rats. | 2001 Feb |
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Pharmacokinetics of diaspirin cross-linked haemoglobin in a rat model of hepatic cirrhosis. | 2001 Feb |
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Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: effects of different cytotoxins on cytochrome P450 mediated monooxygenase functions and on oxidative state. | 2001 Feb |
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Fourier-transform infrared spectroscopy: a pharmacotoxicologic tool for in vivo monitoring radical aggression. | 2001 Feb |
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Carbon tetrachloride dechlorination by the bacterial transition metal chelator pyridine-2,6-bis(thiocarboxylic acid). | 2001 Feb 1 |
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Evaluation of oxidative stress during apoptosis and necrosis caused by carbon tetrachloride in rat liver. | 2001 Feb 14 |
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Transformation of chlorinated aliphatic compounds by ferruginous smectite. | 2001 Feb 15 |
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Simultaneous induction of galectin-3 phosphorylated on tyrosine residue, p21(WAF1/Cip1/Sdi1), and the proliferating cell nuclear antigen at a distinctive period of repair of hepatocytes injured by CCl4. | 2001 Feb 2 |
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Near infrared spectra (4000-10 500 cm-1) of phenol-OH and phenol-OD in carbon tetrachloride. | 2001 Jan |
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Portal hypertensive response to bradykinin in inflamed or cirrhotic rat livers is mediated by B2-type receptors. | 2001 Jan |
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Hepatoprotective activity of Luffa echinata fruits. | 2001 Jul |
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Kinetics and mechanisms of hepatic acute phase response to subtotal partial hepatectomy and cultural impact on environmental hepatic end-stage liver injury in the homeless. | 2001 Jun |
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Unique gene expression patterns in liver and kidney associated with exposure to chemical toxicants. | 2001 Jun |
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5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication. | 2001 Mar |
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Efficiency of rice bran for removal of organochlorine compounds and benzene from industrial wastewater. | 2001 Mar |
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Uptake, tissue distribution, and fate of inhaled carbon tetrachloride: comparison of rat, mouse, and hamster. | 2001 Mar |
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Heterogeneity and plasticity of hepatocyte lineage cells. | 2001 Mar |
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Role of inflammation in chemical-induced hepatotoxicity. | 2001 Mar 31 |
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Role of cytokines in non-genotoxic hepatocarcinogenesis: cause or effect? | 2001 Mar 31 |
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Rhamnazin-4'-O-beta-[apiosyl(1-->2)] glucoside as a means of antioxidative defense against tetrachloromethane induced hepatotoxicity in rats. | 2001 May |
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The influence of chlorine on the intensity of metal atomic lines emitted by an electrolyte cathode atmospheric glow discharge. | 2001 May |
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Determination of elemental sulfur in coal by gas chromatography-mass spectrometry. | 2001 May |
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Optimization of an exogenous metabolic activation system for FETAX. II. Preliminary evaluation. | 2001 May |
|
RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays. | 2001 May |
|
Risk of pancreatic cancer in workers exposed to chlorinated hydrocarbon solvents and related compounds: a meta-analysis. | 2001 May 1 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:35:41 UTC 2023
by
admin
on
Fri Dec 15 16:35:41 UTC 2023
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Record UNII |
CL2T97X0V0
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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IARC | Carbon tetrachloride | ||
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EPA PESTICIDE CODE |
16501
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NCI_THESAURUS |
C45386
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CL2T97X0V0
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carbon tetrachloride
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CARBON TETRACHLORIDE
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DTXSID8020250
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C44350
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m3086
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