Details
Stereochemistry | ACHIRAL |
Molecular Formula | CCl4 |
Molecular Weight | 153.823 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC(Cl)(Cl)Cl
InChI
InChIKey=VZGDMQKNWNREIO-UHFFFAOYSA-N
InChI=1S/CCl4/c2-1(3,4)5
Molecular Formula | CCl4 |
Molecular Weight | 153.823 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Carbon tetrachloride, also called tetrachloromethane, a colourless, dense, highly toxic, volatile, nonflammable liquid possessing a characteristic odour and belonging to the family of organic halogen compounds, used principally in the manufacture of dichlorodifluoromethane. Carbon tetrachloride is commonly used as a chemical intermediate, solvent, and dry-cleaning fluid. It was widely used as a cleaning fluid. Carbon tetrachloride was also used in fire extinguishers and as a fumigant to kill insects in grain. Human exposure to carbon tetrachloride from occupational or environmental sources is low and unlikely to produce acute kidney toxicity. Carbon tetrachloride is a manufactured chemical and does not occur naturally in the environment.
Approval Year
PubMed
Title | Date | PubMed |
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Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis. | 1999 Nov |
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Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells. | 2000 Jan |
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Effects of IGF-I treatment on osteopenia in rats with advanced liver cirrhosis. | 2000 Jun |
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Metabonomics: evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants. | 2000 Oct |
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Interaction between monensin and CCl4 after chronic treatment: dolichol and retinol content of rat liver sinusoidal cells. | 2001 |
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Glycogen-forming function of hepatocytes in cirrhotically altered rat liver after treatment with chorionic gonadotropin. | 2001 Apr |
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Enhanced expression of endothelin receptor subtypes in cirrhotic rat liver. | 2001 Apr |
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Regulation of cholangiocyte proliferation. | 2001 Apr |
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Measurement of volatile organic compounds in sediments of the Scheldt estuary and the Southern North Sea. | 2001 Apr |
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Activity of different Candida antarctica lipase B formulations in organic solvents. | 2001 Apr 20 |
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Analysis of C2-C4 peroxyacyl nitrates and C1-C5 alkyl nitrates with a non-polar capillary column. | 2001 Apr 27 |
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The role of antioxidant vitamins (C and E), selenium and Nigella sativa in the prevention of liver fibrosis and cirrhosis in rabbits: new hopes. | 2001 Feb |
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Anti-fibrotic effects of a hot-water extract from Salvia miltiorrhiza roots on liver fibrosis induced by biliary obstruction in rats. | 2001 Feb |
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Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: effects of different cytotoxins on cytochrome P450 mediated monooxygenase functions and on oxidative state. | 2001 Feb |
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Photocatalytic degradation of gaseous perchloroethylene: products and pathway. | 2001 Feb |
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Carbon tetrachloride dechlorination by the bacterial transition metal chelator pyridine-2,6-bis(thiocarboxylic acid). | 2001 Feb 1 |
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Evaluation of oxidative stress during apoptosis and necrosis caused by carbon tetrachloride in rat liver. | 2001 Feb 14 |
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Near infrared spectra (4000-10 500 cm-1) of phenol-OH and phenol-OD in carbon tetrachloride. | 2001 Jan |
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Simple time weighted average level air-monitoring method for sulfur mustard in work places. | 2001 Jan 12 |
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Various aspects of the constraints imposed on the photochemistry of systems in porous silica. | 2001 Jan 29 |
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Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL. | 2001 Jul 13 |
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Investigation of cell exudates active in carbon tetrachloride and chloroform degradation. | 2001 Jul 5 |
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Kinetics and mechanisms of hepatic acute phase response to subtotal partial hepatectomy and cultural impact on environmental hepatic end-stage liver injury in the homeless. | 2001 Jun |
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Unique gene expression patterns in liver and kidney associated with exposure to chemical toxicants. | 2001 Jun |
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Uptake, tissue distribution, and fate of inhaled carbon tetrachloride: comparison of rat, mouse, and hamster. | 2001 Mar |
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Induction of metallothionein in the liver of carbon tetrachloride intoxicated rats: an immunohistochemical study. | 2001 Mar 21 |
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Role of cytokines in non-genotoxic hepatocarcinogenesis: cause or effect? | 2001 Mar 31 |
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Hepatocyte damage induced by carbon tetrachloride: inhibited lipoprotein secretion and changed lipoprotein composition. | 2001 Mar-Apr |
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Rhamnazin-4'-O-beta-[apiosyl(1-->2)] glucoside as a means of antioxidative defense against tetrachloromethane induced hepatotoxicity in rats. | 2001 May |
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The influence of chlorine on the intensity of metal atomic lines emitted by an electrolyte cathode atmospheric glow discharge. | 2001 May |
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Transplantation of cultured allogeneic hepatocytes without immunosuppression. | 2001 May |
|
RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays. | 2001 May |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:35:41 GMT 2023
by
admin
on
Fri Dec 15 16:35:41 GMT 2023
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Record UNII |
CL2T97X0V0
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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IARC | Carbon tetrachloride | ||
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EPA PESTICIDE CODE |
16501
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NCI_THESAURUS |
C45386
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CL2T97X0V0
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carbon tetrachloride
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1601168
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CARBON TETRACHLORIDE
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DTXSID8020250
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27385
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C44350
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m3086
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PRIMARY | Merck Index |