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Details

Stereochemistry ACHIRAL
Molecular Formula CCl4
Molecular Weight 153.823
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Carbon tetrachloride

SMILES

ClC(Cl)(Cl)Cl

InChI

InChIKey=VZGDMQKNWNREIO-UHFFFAOYSA-N
InChI=1S/CCl4/c2-1(3,4)5

HIDE SMILES / InChI

Molecular Formula CCl4
Molecular Weight 153.823
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Carbon tetrachloride, also called tetrachloromethane, a colourless, dense, highly toxic, volatile, nonflammable liquid possessing a characteristic odour and belonging to the family of organic halogen compounds, used principally in the manufacture of dichlorodifluoromethane. Carbon tetrachloride is commonly used as a chemical intermediate, solvent, and dry-cleaning fluid. It was widely used as a cleaning fluid. Carbon tetrachloride was also used in fire extinguishers and as a fumigant to kill insects in grain. Human exposure to carbon tetrachloride from occupational or environmental sources is low and unlikely to produce acute kidney toxicity. Carbon tetrachloride is a manufactured chemical and does not occur naturally in the environment.

Approval Year

PubMed

PubMed

TitleDatePubMed
Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis.
1999 Nov
Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells.
2000 Jan
Effects of IGF-I treatment on osteopenia in rats with advanced liver cirrhosis.
2000 Jun
Metabonomics: evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants.
2000 Oct
Interaction between monensin and CCl4 after chronic treatment: dolichol and retinol content of rat liver sinusoidal cells.
2001
Glycogen-forming function of hepatocytes in cirrhotically altered rat liver after treatment with chorionic gonadotropin.
2001 Apr
Enhanced expression of endothelin receptor subtypes in cirrhotic rat liver.
2001 Apr
Regulation of cholangiocyte proliferation.
2001 Apr
Measurement of volatile organic compounds in sediments of the Scheldt estuary and the Southern North Sea.
2001 Apr
Activity of different Candida antarctica lipase B formulations in organic solvents.
2001 Apr 20
Analysis of C2-C4 peroxyacyl nitrates and C1-C5 alkyl nitrates with a non-polar capillary column.
2001 Apr 27
The role of antioxidant vitamins (C and E), selenium and Nigella sativa in the prevention of liver fibrosis and cirrhosis in rabbits: new hopes.
2001 Feb
Anti-fibrotic effects of a hot-water extract from Salvia miltiorrhiza roots on liver fibrosis induced by biliary obstruction in rats.
2001 Feb
Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: effects of different cytotoxins on cytochrome P450 mediated monooxygenase functions and on oxidative state.
2001 Feb
Photocatalytic degradation of gaseous perchloroethylene: products and pathway.
2001 Feb
Carbon tetrachloride dechlorination by the bacterial transition metal chelator pyridine-2,6-bis(thiocarboxylic acid).
2001 Feb 1
Evaluation of oxidative stress during apoptosis and necrosis caused by carbon tetrachloride in rat liver.
2001 Feb 14
Near infrared spectra (4000-10 500 cm-1) of phenol-OH and phenol-OD in carbon tetrachloride.
2001 Jan
Simple time weighted average level air-monitoring method for sulfur mustard in work places.
2001 Jan 12
Various aspects of the constraints imposed on the photochemistry of systems in porous silica.
2001 Jan 29
Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL.
2001 Jul 13
Investigation of cell exudates active in carbon tetrachloride and chloroform degradation.
2001 Jul 5
Kinetics and mechanisms of hepatic acute phase response to subtotal partial hepatectomy and cultural impact on environmental hepatic end-stage liver injury in the homeless.
2001 Jun
Unique gene expression patterns in liver and kidney associated with exposure to chemical toxicants.
2001 Jun
Uptake, tissue distribution, and fate of inhaled carbon tetrachloride: comparison of rat, mouse, and hamster.
2001 Mar
Induction of metallothionein in the liver of carbon tetrachloride intoxicated rats: an immunohistochemical study.
2001 Mar 21
Role of cytokines in non-genotoxic hepatocarcinogenesis: cause or effect?
2001 Mar 31
Hepatocyte damage induced by carbon tetrachloride: inhibited lipoprotein secretion and changed lipoprotein composition.
2001 Mar-Apr
Rhamnazin-4'-O-beta-[apiosyl(1-->2)] glucoside as a means of antioxidative defense against tetrachloromethane induced hepatotoxicity in rats.
2001 May
The influence of chlorine on the intensity of metal atomic lines emitted by an electrolyte cathode atmospheric glow discharge.
2001 May
Transplantation of cultured allogeneic hepatocytes without immunosuppression.
2001 May
RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays.
2001 May
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:35:41 GMT 2023
Edited
by admin
on Fri Dec 15 16:35:41 GMT 2023
Record UNII
CL2T97X0V0
Record Status Validated (UNII)
Record Version
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Name Type Language
Carbon tetrachloride
HSDB   ISO   MART.   MI   WHO-DD  
Systematic Name English
CARBONEUM CHLORATUM [HPUS]
Common Name English
CARBON TETRACHLORIDE [IARC]
Common Name English
CARBON TETRACHLORIDE [MI]
Common Name English
METHANE, TETRACHLORO-
Systematic Name English
CARBON TETRACHLORIDE [USP-RS]
Common Name English
CARBONEUM CHLORATUM
HPUS  
Common Name English
CARBON TETRACHLORIDE [MART.]
Common Name English
Carbon tetrachloride [WHO-DD]
Common Name English
CARBON TETRACHLORIDE [ISO]
Common Name English
CARBON TETRACHLORIDE [HSDB]
Common Name English
NSC-97063
Code English
Classification Tree Code System Code
IARC Carbon tetrachloride
EPA PESTICIDE CODE 16501
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
NCI_THESAURUS C45386
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
Code System Code Type Description
FDA UNII
CL2T97X0V0
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
MESH
D002251
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
RXCUI
2383337
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
CAS
56-23-5
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
DAILYMED
CL2T97X0V0
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
ALANWOOD
carbon tetrachloride
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
HSDB
52
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
ChEMBL
CHEMBL44814
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
DRUG CENTRAL
3067
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
RS_ITEM_NUM
1601168
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
WIKIPEDIA
CARBON TETRACHLORIDE
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
EPA CompTox
DTXSID8020250
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
PUBCHEM
5943
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
ECHA (EC/EINECS)
200-262-8
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
NSC
97063
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
CHEBI
27385
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
NCI_THESAURUS
C44350
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY
MERCK INDEX
m3086
Created by admin on Fri Dec 15 16:35:41 GMT 2023 , Edited by admin on Fri Dec 15 16:35:41 GMT 2023
PRIMARY Merck Index