Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | CCl4 |
| Molecular Weight | 153.823 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC(Cl)(Cl)Cl
InChI
InChIKey=VZGDMQKNWNREIO-UHFFFAOYSA-N
InChI=1S/CCl4/c2-1(3,4)5
| Molecular Formula | CCl4 |
| Molecular Weight | 153.823 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Carbon tetrachloride, also called tetrachloromethane, a colourless, dense, highly toxic, volatile, nonflammable liquid possessing a characteristic odour and belonging to the family of organic halogen compounds, used principally in the manufacture of dichlorodifluoromethane. Carbon tetrachloride is commonly used as a chemical intermediate, solvent, and dry-cleaning fluid. It was widely used as a cleaning fluid. Carbon tetrachloride was also used in fire extinguishers and as a fumigant to kill insects in grain. Human exposure to carbon tetrachloride from occupational or environmental sources is low and unlikely to produce acute kidney toxicity. Carbon tetrachloride is a manufactured chemical and does not occur naturally in the environment.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL. | 2001-07-13 |
|
| Investigation of cell exudates active in carbon tetrachloride and chloroform degradation. | 2001-07-05 |
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| Hepatoprotective activity of Luffa echinata fruits. | 2001-07 |
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| JunD regulates transcription of the tissue inhibitor of metalloproteinases-1 and interleukin-6 genes in activated hepatic stellate cells. | 2001-06-29 |
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| Time-resolved total internal reflection fluorometry study on polarity at a liquid/liquid interface. | 2001-06-01 |
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| Kinetics and mechanisms of hepatic acute phase response to subtotal partial hepatectomy and cultural impact on environmental hepatic end-stage liver injury in the homeless. | 2001-06 |
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| Earlier expression of the transcription factor HFH-11B diminishes induction of p21(CIP1/WAF1) levels and accelerates mouse hepatocyte entry into S-phase following carbon tetrachloride liver injury. | 2001-06 |
|
| Influence of ferrous iron and ph on carbon tetrachloride degradation by Methanosarcina thermophila. | 2001-06 |
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| Unique gene expression patterns in liver and kidney associated with exposure to chemical toxicants. | 2001-06 |
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| Hepatocyte growth factor promotes liver regeneration and protein synthesis after hepatectomy in cirrhotic rats. | 2001-05-31 |
|
| Hepatocyte damage induced by carbon tetrachloride: inhibited lipoprotein secretion and changed lipoprotein composition. | 2001-05-24 |
|
| Radiolytic and thermal dechlorination of organic chlorides adsorbed on molecular sieve 13X. | 2001-05-15 |
|
| Visualization of solute migration in chromatographic columns influence of the frit porosity. | 2001-05-11 |
|
| Noninvasive determination of the location and distribution of DNAPL using advanced seismic reflection techniques. | 2001-05-09 |
|
| Risk of pancreatic cancer in workers exposed to chlorinated hydrocarbon solvents and related compounds: a meta-analysis. | 2001-05-01 |
|
| Rhamnazin-4'-O-beta-[apiosyl(1-->2)] glucoside as a means of antioxidative defense against tetrachloromethane induced hepatotoxicity in rats. | 2001-05 |
|
| The influence of chlorine on the intensity of metal atomic lines emitted by an electrolyte cathode atmospheric glow discharge. | 2001-05 |
|
| Determination of elemental sulfur in coal by gas chromatography-mass spectrometry. | 2001-05 |
|
| Transplantation of cultured allogeneic hepatocytes without immunosuppression. | 2001-05 |
|
| Optimization of an exogenous metabolic activation system for FETAX. II. Preliminary evaluation. | 2001-05 |
|
| Effects of dietary curcumin on glutathione S-transferase and malondialdehyde-DNA adducts in rat liver and colon mucosa: relationship with drug levels. | 2001-05 |
|
| RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays. | 2001-05 |
|
| Liver-type arginase is a highly sensitive marker for hepatocellular damage in rats. | 2001-05 |
|
| Role of nitric oxide (NO) in pulmonary dysfunction associated with experimental cirrhosis. | 2001-05 |
|
| Analysis of C2-C4 peroxyacyl nitrates and C1-C5 alkyl nitrates with a non-polar capillary column. | 2001-04-27 |
|
| Pathogenesis of carbon tetrachloride-induced hepatocyte injury bioactivation of CCI4 by cytochrome P450 and effects on lipid homeostasis. | 2001-04-17 |
|
| Prooxidant and antioxidant functions of nitric oxide in liver toxicity. | 2001-04 |
|
| Increase of tissue lipid hydroperoxides as determination of oxidative stress. | 2001-04 |
|
| Glycogen-forming function of hepatocytes in cirrhotically altered rat liver after treatment with chorionic gonadotropin. | 2001-04 |
|
| Carbon tetrachloride-induced acute liver injury in Mini and Wistar rats. | 2001-04 |
|
| Protective effects of acetylbergenin against carbon tetrachloride-induced hepatotoxicity in rats. | 2001-04 |
|
| Reduction of carbon tetrachloride-induced rat liver injury by IRFI 042, a novel dual vitamin E-like antioxidant. | 2001-04 |
|
| Enhanced expression of endothelin receptor subtypes in cirrhotic rat liver. | 2001-04 |
|
| Regulation of cholangiocyte proliferation. | 2001-04 |
|
| Measurement of volatile organic compounds in sediments of the Scheldt estuary and the Southern North Sea. | 2001-04 |
|
| Role of inflammation in chemical-induced hepatotoxicity. | 2001-03-31 |
|
| Role of cytokines in non-genotoxic hepatocarcinogenesis: cause or effect? | 2001-03-31 |
|
| The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis. | 2001-03-31 |
|
| Apoptosis in dissociation between DNA synthesis and cellular functions of activated hepatic stellate cells--a study with carbon tetrachloride-induced rat liver injury. | 2001-03-30 |
|
| Visible light-induced degradation of carbon tetrachloride on dye-sensitized TiO2. | 2001-03-01 |
|
| 5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication. | 2001-03 |
|
| Efficiency of rice bran for removal of organochlorine compounds and benzene from industrial wastewater. | 2001-03 |
|
| Transformation of chlorinated aliphatic compounds by ferruginous smectite. | 2001-02-15 |
|
| Evaluation of oxidative stress during apoptosis and necrosis caused by carbon tetrachloride in rat liver. | 2001-02-14 |
|
| Carbon tetrachloride dechlorination by the bacterial transition metal chelator pyridine-2,6-bis(thiocarboxylic acid). | 2001-02-01 |
|
| The role of antioxidant vitamins (C and E), selenium and Nigella sativa in the prevention of liver fibrosis and cirrhosis in rabbits: new hopes. | 2001-02 |
|
| Vitamin E reduces lipid peroxidation in experimental hepatotoxicity in rats. | 2001-02 |
|
| Fructose, 1,6-diphosphate mitigates CCl4 suppressed nitric oxide synthase activity in rats. | 2001-01 |
|
| Interaction between monensin and CCl4 after chronic treatment: dolichol and retinol content of rat liver sinusoidal cells. | 2001 |
|
| Applications of microarray technology in breast cancer research. | 2001 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:32:11 GMT 2025
by
admin
on
Mon Mar 31 18:32:11 GMT 2025
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| Record UNII |
CL2T97X0V0
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
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IARC | Carbon tetrachloride | ||
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EPA PESTICIDE CODE |
16501
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NCI_THESAURUS |
C45386
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CL2T97X0V0
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D002251
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CL2T97X0V0
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carbon tetrachloride
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1601168
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CARBON TETRACHLORIDE
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DTXSID8020250
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27385
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C44350
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m3086
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PRIMARY | Merck Index |