Details
Stereochemistry | ACHIRAL |
Molecular Formula | CCl4 |
Molecular Weight | 153.823 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC(Cl)(Cl)Cl
InChI
InChIKey=VZGDMQKNWNREIO-UHFFFAOYSA-N
InChI=1S/CCl4/c2-1(3,4)5
Molecular Formula | CCl4 |
Molecular Weight | 153.823 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Carbon tetrachloride, also called tetrachloromethane, a colourless, dense, highly toxic, volatile, nonflammable liquid possessing a characteristic odour and belonging to the family of organic halogen compounds, used principally in the manufacture of dichlorodifluoromethane. Carbon tetrachloride is commonly used as a chemical intermediate, solvent, and dry-cleaning fluid. It was widely used as a cleaning fluid. Carbon tetrachloride was also used in fire extinguishers and as a fumigant to kill insects in grain. Human exposure to carbon tetrachloride from occupational or environmental sources is low and unlikely to produce acute kidney toxicity. Carbon tetrachloride is a manufactured chemical and does not occur naturally in the environment.
Approval Year
PubMed
Title | Date | PubMed |
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[Cytoplasmic crystals (cholesterol?) in acute and chronic liver lesions. Electron microscopic study]. | 1976 Oct |
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Inhibition of cytochrome P450 2E1 expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury. | 1999 Apr 12 |
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Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase. | 2000 Aug |
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Increase of tissue lipid hydroperoxides as determination of oxidative stress. | 2001 Apr |
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Protective effects of acetylbergenin against carbon tetrachloride-induced hepatotoxicity in rats. | 2001 Apr |
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Reduction of carbon tetrachloride-induced rat liver injury by IRFI 042, a novel dual vitamin E-like antioxidant. | 2001 Apr |
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Distinct roles of tumor necrosis factor-alpha and nitric oxide in acute liver injury induced by carbon tetrachloride in mice. | 2001 Apr 1 |
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Analysis of C2-C4 peroxyacyl nitrates and C1-C5 alkyl nitrates with a non-polar capillary column. | 2001 Apr 27 |
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Anti-fibrotic effects of a hot-water extract from Salvia miltiorrhiza roots on liver fibrosis induced by biliary obstruction in rats. | 2001 Feb |
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Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: effects of different cytotoxins on cytochrome P450 mediated monooxygenase functions and on oxidative state. | 2001 Feb |
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Cleanup worker exposures to hazardous chemicals at a former nuclear weapons plant: piloting of an exposure surveillance system. | 2001 Feb |
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Eigenvalues and principal component loadings of heavily overlapped vibrational spectra. | 2001 Feb |
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Charge-transfer complex formation between o-chloranil and a series of polynuclear aromatic hydrocarbons. | 2001 Feb |
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Evaluation of oxidative stress during apoptosis and necrosis caused by carbon tetrachloride in rat liver. | 2001 Feb 14 |
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Transformation of chlorinated aliphatic compounds by ferruginous smectite. | 2001 Feb 15 |
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A novel role of complement: mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration. | 2001 Feb 15 |
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Simultaneous induction of galectin-3 phosphorylated on tyrosine residue, p21(WAF1/Cip1/Sdi1), and the proliferating cell nuclear antigen at a distinctive period of repair of hepatocytes injured by CCl4. | 2001 Feb 2 |
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Pyriform cortex beta-waves: odor-specific sensitization following repeated olfactory stimulation. | 2001 Feb 23 |
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Fructose, 1,6-diphosphate mitigates CCl4 suppressed nitric oxide synthase activity in rats. | 2001 Jan |
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Expression patterns of cell cycle-related proteins in a rat cirrhotic model induced by CCl4 or thioacetamide. | 2001 Jan |
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Near infrared spectra (4000-10 500 cm-1) of phenol-OH and phenol-OD in carbon tetrachloride. | 2001 Jan |
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Potential transition state phosphoramidate inhibitors of beta-tubulin as antifilarial agents. | 2001 Jan |
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Simple time weighted average level air-monitoring method for sulfur mustard in work places. | 2001 Jan 12 |
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Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL. | 2001 Jul 13 |
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Influence of ferrous iron and ph on carbon tetrachloride degradation by Methanosarcina thermophila. | 2001 Jun |
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Time-resolved total internal reflection fluorometry study on polarity at a liquid/liquid interface. | 2001 Jun 1 |
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JunD regulates transcription of the tissue inhibitor of metalloproteinases-1 and interleukin-6 genes in activated hepatic stellate cells. | 2001 Jun 29 |
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5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication. | 2001 Mar |
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Uptake, tissue distribution, and fate of inhaled carbon tetrachloride: comparison of rat, mouse, and hamster. | 2001 Mar |
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Heterogeneity and plasticity of hepatocyte lineage cells. | 2001 Mar |
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Induction of metallothionein in the liver of carbon tetrachloride intoxicated rats: an immunohistochemical study. | 2001 Mar 21 |
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Apoptosis in dissociation between DNA synthesis and cellular functions of activated hepatic stellate cells--a study with carbon tetrachloride-induced rat liver injury. | 2001 Mar 30 |
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Role of inflammation in chemical-induced hepatotoxicity. | 2001 Mar 31 |
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The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis. | 2001 Mar 31 |
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RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays. | 2001 May |
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Liver-type arginase is a highly sensitive marker for hepatocellular damage in rats. | 2001 May |
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Risk of pancreatic cancer in workers exposed to chlorinated hydrocarbon solvents and related compounds: a meta-analysis. | 2001 May 1 |
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Visualization of solute migration in chromatographic columns influence of the frit porosity. | 2001 May 11 |
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Radiolytic and thermal dechlorination of organic chlorides adsorbed on molecular sieve 13X. | 2001 May 15 |
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Noninvasive determination of the location and distribution of DNAPL using advanced seismic reflection techniques. | 2001 May-Jun |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:32:11 GMT 2025
by
admin
on
Mon Mar 31 18:32:11 GMT 2025
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Record UNII |
CL2T97X0V0
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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IARC | Carbon tetrachloride | ||
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EPA PESTICIDE CODE |
16501
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NCI_THESAURUS |
C45386
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CL2T97X0V0
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carbon tetrachloride
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CARBON TETRACHLORIDE
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m3086
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PRIMARY | Merck Index |