Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H14Cl4N2O |
| Molecular Weight | 416.129 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC(Cl)=C(CO[C@@H](CN2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C=C1
InChI
InChIKey=BYBLEWFAAKGYCD-SFHVURJKSA-N
InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2/t18-/m0/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Efficacy of 7-day treatment with metronidazole+miconazole (Neo-Penotran) - a triple-active pessary for the treatment of single and mixed vaginal infections. | 2001 Jul |
|
| In vitro comparison of the antimycotic activity of a miconazole-HP-beta-cyclodextrin solution with a miconazole surfactant solution. | 2001 Jul |
|
| Comparison of dermatopharmacokinetic vs. clinicial efficacy methods for bioequivalence assessment of miconazole nitrate vaginal cream, 2% in humans. | 2002 Mar |
|
| Preparation and in vitro/in vivo evaluation of the buccal bioadhesive properties of slow-release tablets containing miconazole nitrate. | 2003 Mar |
|
| Mucoadhesive buccal patches of miconazole nitrate: in vitro/in vivo performance and effect of ageing. | 2003 Oct 2 |
|
| [Screening Examination and Management of Dermatophytosis by Trichophyton tonsurans in the Judo Club of a University]. | 2004 |
|
| Vaginal distribution of miconazole nitrate suspension from administration of a single vaginal insert. | 2004 Feb |
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| The contraceptive vaginal ring, NuvaRing, and antimycotic co-medication. | 2004 Feb |
|
| Structure and generation mechanism of a novel degradation product formed by oxidatively induced coupling of miconazole nitrate with butylated hydroxytoluene in a topical ointment studied by HPLC-ESI-MS and organic synthesis. | 2004 Feb |
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| Comparative efficacy of topical therapy with a slow-release mucoadhesive buccal tablet containing miconazole nitrate versus systemic therapy with ketoconazole in HIV-positive patients with oropharyngeal candidiasis. | 2004 Feb 1 |
|
| Surrogate nits impregnated with white piedra--a case report. | 2004 Jul |
|
| Difference in percutaneous absorption and intracutaneous distribution in guinea pigs among topical antifungal drugs (tioconazole solution, tioconazole cream, miconazole nitrate solution and bifonazole solution). | 2004 Sep |
|
| [Evaluation of the efficacy of miconazole nitrate shampoo for prevention against T. tonsurans infection]. | 2005 |
|
| Safety and efficacy of bedtime versus daytime administration of the miconazole nitrate 1200 mg vaginal ovule insert to treat vulvovaginal candidiasis. | 2005 Jan |
|
| Effect of a single overnight topical application of miconazole nitrate paste on acne papules. | 2006 Mar |
|
| [How I treat....A stoutness-associated intertrigo]. | 2007 Feb |
|
| The effect of ambulation on vaginal distribution of miconazole nitrate (1200 mg). | 2007 Jun |
|
| Absorption and efficacy of miconazole nitrate 0.25% ointment in infants with diaper dermatitis. | 2007 May |
|
| Spermicidal activity of the safe natural antimicrobial peptide subtilosin. | 2008 |
|
| Stability indicating methods for the determination of some anti-fungal agents using densitometric and RP-HPLC methods. | 2008 Feb |
|
| Positively charged microemulsions for topical application. | 2008 Jan 4 |
|
| Reconstructed interfollicular feline epidermis as a model for the screening of antifungal drugs against Microsporum canis. | 2008 Jun |
|
| Efficacy of Brazilian propolis gel for the management of denture stomatitis: a pilot study. | 2008 Nov |
|
| Preliminary isolation and in vitro antiyeast activity of active fraction from crude extract of Gracilaria changii. | 2008 Oct |
|
| Efficacy and tolerance of metronidazole and miconazole nitrate in treatment of vaginitis. | 2008 Sep |
|
| Development and validation of a simple stability-indicating high performance liquid chromatographic method for the determination of miconazole nitrate in bulk and cream formulations. | 2009 Aug 15 |
|
| L(9) orthogonal design assisted formulation and evaluation of chitosan-based buccoadhesive films of miconazole nitrate. | 2009 Jul |
|
| Simultaneous determination of metronidazole and miconazole nitrate in gel by HPTLC. | 2009 Jul |
|
| Development of Buccal Adhesive Tablet with Prolonged Antifungal activity: Optimization and ex vivo Deposition Studies. | 2009 May |
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| Design and development of solid lipid nanoparticles for topical delivery of an anti-fungal agent. | 2010 Aug |
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| Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability. | 2010 Jul 27 |
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| Drawing the line between commensal and pathogenic Gardnerella vaginalis through genome analysis and virulence studies. | 2010 Jun 11 |
|
| Formulation and evaluation of mucoadhesive buccal films of enalapril maleate. | 2010 Sep |
|
| Synthesis of some 3-substituted amino-4,5-tetramethylene thieno[2,3-d][ 1,2,3]-triazin-4(3H)-ones as potential antimicrobial agents. | 2010 Sep |
|
| Structure-activity studies and therapeutic potential of host defense peptides of human thrombin. | 2011 Jun |
Patents
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| Code System | Code | Type | Description | ||
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1150344
Created by
admin on Sat Dec 16 11:16:02 GMT 2023 , Edited by admin on Sat Dec 16 11:16:02 GMT 2023
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47447-53-0
Created by
admin on Sat Dec 16 11:16:02 GMT 2023 , Edited by admin on Sat Dec 16 11:16:02 GMT 2023
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C90U92KSVX
Created by
admin on Sat Dec 16 11:16:02 GMT 2023 , Edited by admin on Sat Dec 16 11:16:02 GMT 2023
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PRIMARY |
SUBSTANCE RECORD
