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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H14Cl4N2O
Molecular Weight 416.129
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MICONAZOLE, (R)-

SMILES

ClC1=CC(Cl)=C(CO[C@@H](CN2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C=C1

InChI

InChIKey=BYBLEWFAAKGYCD-SFHVURJKSA-N
InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2/t18-/m0/s1

HIDE SMILES / InChI

Molecular Formula C18H14Cl4N2O
Molecular Weight 416.129
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Preparation and in vitro/in vivo evaluation of the buccal bioadhesive properties of slow-release tablets containing miconazole nitrate.
2003 Mar
Difference in percutaneous absorption and intracutaneous distribution in guinea pigs among topical antifungal drugs (tioconazole solution, tioconazole cream, miconazole nitrate solution and bifonazole solution).
2004 Sep
Safety and efficacy of bedtime versus daytime administration of the miconazole nitrate 1200 mg vaginal ovule insert to treat vulvovaginal candidiasis.
2005 Jan
Dynamics of skin barrier repair following topical applications of miconazole nitrate.
2006
Species distribution and susceptibility to azoles of vaginal yeasts isolated prostitutes.
2007
Preparation and evaluation of miconazole nitrate-loaded solid lipid nanoparticles for topical delivery.
2009
Simultaneous determination of metronidazole and miconazole nitrate in gel by HPTLC.
2009 Jul
Prevention and treatment of intertrigo in large skin folds of adults: a systematic review.
2010 Jul 13
Drawing the line between commensal and pathogenic Gardnerella vaginalis through genome analysis and virulence studies.
2010 Jun 11
Synergistic effect of hydroxypropyl-beta-cyclodextrin encapsulated soluble ferrocene and the gold nanocomposite modified glassy carbon electrode for the estimation of NO in biological systems.
2010 Sep
Structure-activity studies and therapeutic potential of host defense peptides of human thrombin.
2011 Jun
Patents
Substance Class Chemical
Created
by admin
on Sun Dec 18 07:12:25 UTC 2022
Edited
by admin
on Sun Dec 18 07:12:25 UTC 2022
Record UNII
C90U92KSVX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MICONAZOLE, (R)-
Common Name English
MICONAZOLE, (-)-
Common Name English
1H-IMIDAZOLE, 1-((2R)-2-(2,4-DICHLOROPHENYL)-2-((2,4-DICHLOROPHENYL)METHOXY)ETHYL)-
Systematic Name English
Code System Code Type Description
PUBCHEM
1150344
Created by admin on Sun Dec 18 07:12:25 UTC 2022 , Edited by admin on Sun Dec 18 07:12:25 UTC 2022
PRIMARY
CAS
47447-53-0
Created by admin on Sun Dec 18 07:12:25 UTC 2022 , Edited by admin on Sun Dec 18 07:12:25 UTC 2022
PRIMARY
FDA UNII
C90U92KSVX
Created by admin on Sun Dec 18 07:12:25 UTC 2022 , Edited by admin on Sun Dec 18 07:12:25 UTC 2022
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER