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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H14Cl4N2O
Molecular Weight 416.129
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MICONAZOLE, (R)-

SMILES

ClC1=CC(Cl)=C(CO[C@@H](CN2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C=C1

InChI

InChIKey=BYBLEWFAAKGYCD-SFHVURJKSA-N
InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2/t18-/m0/s1

HIDE SMILES / InChI

Molecular Formula C18H14Cl4N2O
Molecular Weight 416.129
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
In vitro comparison of the antimycotic activity of a miconazole-HP-beta-cyclodextrin solution with a miconazole surfactant solution.
2001 Jul
Structure and generation mechanism of a novel degradation product formed by oxidatively induced coupling of miconazole nitrate with butylated hydroxytoluene in a topical ointment studied by HPLC-ESI-MS and organic synthesis.
2004 Feb
Difference in percutaneous absorption and intracutaneous distribution in guinea pigs among topical antifungal drugs (tioconazole solution, tioconazole cream, miconazole nitrate solution and bifonazole solution).
2004 Sep
Miconazole nitrate: comprehensive profile.
2005
Species distribution and susceptibility to azoles of vaginal yeasts isolated prostitutes.
2007
[How I treat....A stoutness-associated intertrigo].
2007 Feb
Absorption and efficacy of miconazole nitrate 0.25% ointment in infants with diaper dermatitis.
2007 May
Assessment of the treatment protocol described in the guidelines for Trichophyton tonsurans infection.
2008
Stability indicating methods for the determination of some anti-fungal agents using densitometric and RP-HPLC methods.
2008 Feb
Preparation and evaluation of miconazole nitrate-loaded solid lipid nanoparticles for topical delivery.
2009
Development and validation of a simple stability-indicating high performance liquid chromatographic method for the determination of miconazole nitrate in bulk and cream formulations.
2009 Aug 15
Sertaconazole 2% cream vs. miconazole 2% cream for cutaneous mycoses: a double-blind clinical trial.
2009 Dec
Evidence-based veterinary dermatology: a systematic review of interventions for Malassezia dermatitis in dogs.
2009 Feb
L(9) orthogonal design assisted formulation and evaluation of chitosan-based buccoadhesive films of miconazole nitrate.
2009 Jul
Development of Buccal Adhesive Tablet with Prolonged Antifungal activity: Optimization and ex vivo Deposition Studies.
2009 May
Antioxidant, Antimicrobial Activity and Toxicity Test of Pilea microphylla.
2010
Design and development of solid lipid nanoparticles for topical delivery of an anti-fungal agent.
2010 Aug
Prevention and treatment of intertrigo in large skin folds of adults: a systematic review.
2010 Jul 13
Drawing the line between commensal and pathogenic Gardnerella vaginalis through genome analysis and virulence studies.
2010 Jun 11
Formulation and evaluation of mucoadhesive buccal films of enalapril maleate.
2010 Sep
Synergistic effect of hydroxypropyl-beta-cyclodextrin encapsulated soluble ferrocene and the gold nanocomposite modified glassy carbon electrode for the estimation of NO in biological systems.
2010 Sep
Structure-activity studies and therapeutic potential of host defense peptides of human thrombin.
2011 Jun
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:16:02 UTC 2023
Edited
by admin
on Sat Dec 16 11:16:02 UTC 2023
Record UNII
C90U92KSVX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MICONAZOLE, (R)-
Common Name English
MICONAZOLE, (-)-
Common Name English
1H-IMIDAZOLE, 1-((2R)-2-(2,4-DICHLOROPHENYL)-2-((2,4-DICHLOROPHENYL)METHOXY)ETHYL)-
Systematic Name English
Code System Code Type Description
PUBCHEM
1150344
Created by admin on Sat Dec 16 11:16:02 UTC 2023 , Edited by admin on Sat Dec 16 11:16:02 UTC 2023
PRIMARY
CAS
47447-53-0
Created by admin on Sat Dec 16 11:16:02 UTC 2023 , Edited by admin on Sat Dec 16 11:16:02 UTC 2023
PRIMARY
FDA UNII
C90U92KSVX
Created by admin on Sat Dec 16 11:16:02 UTC 2023 , Edited by admin on Sat Dec 16 11:16:02 UTC 2023
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER