U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Details

Stereochemistry ABSOLUTE
Molecular Formula C18H14Cl4N2O
Molecular Weight 416.129
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MICONAZOLE, (R)-

SMILES

ClC1=CC=C(CO[C@@H](CN2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C(Cl)=C1

InChI

InChIKey=BYBLEWFAAKGYCD-SFHVURJKSA-N
InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2/t18-/m0/s1

HIDE SMILES / InChI

Molecular Formula C18H14Cl4N2O
Molecular Weight 416.129
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
The contraceptive vaginal ring, NuvaRing, and antimycotic co-medication.
2004 Feb
Miconazole nitrate: comprehensive profile.
2005
Intrasperm Ca2+ modulation and human ejaculated sperm viability: influence of miconazole, clotrimazole and loperamide.
2006 Aug
Effect of a single overnight topical application of miconazole nitrate paste on acne papules.
2006 Mar
Anti-inflammatory and anti-itch activity of sertaconazole nitrate.
2006 Sep
Species distribution and susceptibility to azoles of vaginal yeasts isolated prostitutes.
2007
The effect of ambulation on vaginal distribution of miconazole nitrate (1200 mg).
2007 Jun
Absorption and efficacy of miconazole nitrate 0.25% ointment in infants with diaper dermatitis.
2007 May
Antioxidant, Antimicrobial Activity and Toxicity Test of Pilea microphylla.
2010
Design and development of solid lipid nanoparticles for topical delivery of an anti-fungal agent.
2010 Aug
Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability.
2010 Jul 27
Drawing the line between commensal and pathogenic Gardnerella vaginalis through genome analysis and virulence studies.
2010 Jun 11
Formulation and evaluation of mucoadhesive buccal films of enalapril maleate.
2010 Sep
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 23:43:39 GMT 2025
Edited
by admin
on Mon Mar 31 23:43:39 GMT 2025
Record UNII
C90U92KSVX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MICONAZOLE, (-)-
Preferred Name English
MICONAZOLE, (R)-
Common Name English
1H-IMIDAZOLE, 1-((2R)-2-(2,4-DICHLOROPHENYL)-2-((2,4-DICHLOROPHENYL)METHOXY)ETHYL)-
Systematic Name English
Code System Code Type Description
PUBCHEM
1150344
Created by admin on Mon Mar 31 23:43:39 GMT 2025 , Edited by admin on Mon Mar 31 23:43:39 GMT 2025
PRIMARY
CAS
47447-53-0
Created by admin on Mon Mar 31 23:43:39 GMT 2025 , Edited by admin on Mon Mar 31 23:43:39 GMT 2025
PRIMARY
FDA UNII
C90U92KSVX
Created by admin on Mon Mar 31 23:43:39 GMT 2025 , Edited by admin on Mon Mar 31 23:43:39 GMT 2025
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER