Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C7H10N3O6S.Na |
| Molecular Weight | 287.226 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].NC(=O)[C@@H]1CC[C@@H]2C[N@]1C(=O)N2OS([O-])(=O)=O
InChI
InChIKey=RTCIKUMODPANKX-JBUOLDKXSA-M
InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases. | 2009 Aug |
|
| In vitro activity of avibactam (NXL104) in combination with β-lactams against Gram-negative bacteria, including OXA-48 β-lactamase-producing Klebsiella pneumoniae. | 2012 Jan |
|
| Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor. | 2012 Jul 17 |
|
| Kinetics of avibactam inhibition against Class A, C, and D β-lactamases. | 2013 Sep 27 |
|
| In vivo efficacy of humanized exposures of Ceftazidime-Avibactam in comparison with Ceftazidime against contemporary Enterobacteriaceae isolates. | 2014 Nov |
|
| Role of the Outer Membrane and Porins in Susceptibility of β-Lactamase-Producing Enterobacteriaceae to Ceftazidime-Avibactam. | 2015 Dec 14 |
|
| Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects. | 2015 Oct |
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790235-32-4
Created by
admin on Sat Dec 16 07:57:40 GMT 2023 , Edited by admin on Sat Dec 16 07:57:40 GMT 2023
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SUPERSEDED | |||
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396731-20-7
Created by
admin on Sat Dec 16 07:57:40 GMT 2023 , Edited by admin on Sat Dec 16 07:57:40 GMT 2023
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C8SM6IRW7G
Created by
admin on Sat Dec 16 07:57:40 GMT 2023 , Edited by admin on Sat Dec 16 07:57:40 GMT 2023
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24944097
Created by
admin on Sat Dec 16 07:57:40 GMT 2023 , Edited by admin on Sat Dec 16 07:57:40 GMT 2023
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PRIMARY |
ACTIVE MOIETY
SUBSTANCE RECORD
