Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C7H10N3O6S.Na |
| Molecular Weight | 287.226 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].NC(=O)[C@@H]1CC[C@@H]2C[N@]1C(=O)N2OS([O-])(=O)=O
InChI
InChIKey=RTCIKUMODPANKX-JBUOLDKXSA-M
InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
| Molecular Formula | Na |
| Molecular Weight | 22.98976928 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C7H10N3O6S |
| Molecular Weight | 264.236 |
| Charge | -1 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Role of the Outer Membrane and Porins in Susceptibility of β-Lactamase-Producing Enterobacteriaceae to Ceftazidime-Avibactam. | 2015-12-14 |
|
| Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects. | 2015-10 |
|
| In vivo efficacy of humanized exposures of Ceftazidime-Avibactam in comparison with Ceftazidime against contemporary Enterobacteriaceae isolates. | 2014-11 |
|
| Kinetics of avibactam inhibition against Class A, C, and D β-lactamases. | 2013-09-27 |
|
| Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor. | 2012-07-17 |
|
| In vitro activity of avibactam (NXL104) in combination with β-lactams against Gram-negative bacteria, including OXA-48 β-lactamase-producing Klebsiella pneumoniae. | 2012-01 |
|
| In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases. | 2009-08 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:47:24 GMT 2025
by
admin
on
Mon Mar 31 21:47:24 GMT 2025
|
| Record UNII |
C8SM6IRW7G
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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Common Name | English | ||
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Preferred Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
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790235-32-4
Created by
admin on Mon Mar 31 21:47:24 GMT 2025 , Edited by admin on Mon Mar 31 21:47:24 GMT 2025
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SUPERSEDED | |||
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396731-20-7
Created by
admin on Mon Mar 31 21:47:24 GMT 2025 , Edited by admin on Mon Mar 31 21:47:24 GMT 2025
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PRIMARY | |||
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C8SM6IRW7G
Created by
admin on Mon Mar 31 21:47:24 GMT 2025 , Edited by admin on Mon Mar 31 21:47:24 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
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RACEMATE -> ENANTIOMER |
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
