Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C7H11N3O6S |
| Molecular Weight | 265.244 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC(=O)[C@@H]1CC[C@@H]2C[N@]1C(=O)N2OS(O)(=O)=O
InChI
InChIKey=NDCUAPJVLWFHHB-UHNVWZDZSA-N
InChI=1S/C7H11N3O6S/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15/h4-5H,1-3H2,(H2,8,11)(H,13,14,15)/t4-,5+/m1/s1
| Molecular Formula | C7H11N3O6S |
| Molecular Weight | 265.244 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Role of the Outer Membrane and Porins in Susceptibility of β-Lactamase-Producing Enterobacteriaceae to Ceftazidime-Avibactam. | 2015-12-14 |
|
| Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects. | 2015-10 |
|
| In vivo efficacy of humanized exposures of Ceftazidime-Avibactam in comparison with Ceftazidime against contemporary Enterobacteriaceae isolates. | 2014-11 |
|
| Kinetics of avibactam inhibition against Class A, C, and D β-lactamases. | 2013-09-27 |
|
| Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor. | 2012-07-17 |
|
| In vitro activity of avibactam (NXL104) in combination with β-lactams against Gram-negative bacteria, including OXA-48 β-lactamase-producing Klebsiella pneumoniae. | 2012-01 |
|
| In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases. | 2009-08 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:48:35 GMT 2025
by
admin
on
Mon Mar 31 21:48:35 GMT 2025
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| Record UNII |
06MFO7817I
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| Record Status |
Validated (UNII)
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| Record Version |
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396731-14-9
Created by
admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
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PRIMARY | |||
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06MFO7817I
Created by
admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
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PRIMARY | |||
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794508-22-8
Created by
admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
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SUPERSEDED |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ENANTIOMER -> RACEMATE |
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ENANTIOMER -> RACEMATE |
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
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