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Details

Stereochemistry ACHIRAL
Molecular Formula C8H11N7S
Molecular Weight 237.285
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMBAZONE

SMILES

NC(=N)NN=C1C=CC(C=C1)=NNC(N)=S

InChI

InChIKey=MLMFUKWWZIZRHX-UWRPRBHNSA-N
InChI=1S/C8H11N7S/c9-7(10)14-12-5-1-3-6(4-2-5)13-15-8(11)16/h1-4H,(H4,9,10,14)(H3,11,15,16)/b12-5-,13-6+

HIDE SMILES / InChI

Description

Ambazone (1,4-benzoquinone guanylhydrazone thiosemicarbazone) is an antibacterial agent. It exerts antitumor activity both in vitro and in vivo. Ambazone is indicated in the treatment of infections of the mouth and throat, including tonsillitis, gingivitis, stomatitis, as well as after tonsillectomy, after tooth extraction.

Originator

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
Faringosept (ambazone 10 mg). 3-5 tablets daily for 3-4 days. The tablets should be sucked slowly. The tablets should not be swallowed but allowed to slowly dissolve in the mouth. Use 15-30 minutes after a meal; after using the preparation, do not eat or drink fluids for 2-3 hours.
Route of Administration: Topical