POTASSIUM PYROPHOSPHATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	4K.O7P2
Molecular Weight	330.3365
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[K+].[K+].[K+].[K+].[O-]P([O-])(=O)OP([O-])([O-])=O

InChI

InChIKey=RYCLIXPGLDDLTM-UHFFFAOYSA-J

InChI=1S/4K.H4O7P2/c;;;;1-8(2,3)7-9(4,5)6/h;;;;(H2,1,2,3)(H2,4,5,6)/q4*+1;/p-4

HIDE SMILES / InChI

Description
Sources: https://www.alfa.com/en/catalog/013436/ | https://www.accessdata.fda.gov/scripts/fcn/fcndetailnavigation.cfm?rpt=eafuslisting&id=1760 | https://clinicaltrials.gov/ct2/show/NCT02738541

Potassium pyrophosphate is mainly used as an emulsifier, quality improver and metal ion chelating agent. It can be found in herbicidal compositions as a spray adjuvant. It is also used as an anionic dispersant in water-based (latex) paints. GRAS. Potassium Pyrophosphate has being evaluated in phase II clinical trial as an anti-calculus treatment.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
bone resorption 7 Target ID: GO:0045453 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1796751	Inhibitor 8504

Conditions

Condition	Modality	Targets	Highest Phase	Product
Bone resorption 2 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1796751	Primary		Basic research	Unknown Approved Use Unknown
Dental calculus 1 Sources: https://clinicaltrials.gov/ct2/show/NCT02738541	Primary		Phase II 1147	Unknown Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
abcr GmbH	AB203331	http://www.abcr.com/shop/en/AB203331
abcr GmbH	AB211878	http://www.abcr.com/shop/en/AB211878
Acadechem	ACDS-067621	http://www.acadechemical.com/product/142320
Achemica	ACMC-1BB9Z	http://www.achemica.com/prodinfo/?id=44915
Acros Organics	AC269230010	https://www.fishersci.com/shop/products/potassium-diphosphate-98-extra-pure-acros-organics-1/AC269230010
Acros Organics	AC269230025	https://www.fishersci.com/shop/products/potassium-diphosphate-98-extra-pure-acros-organics/AC269230025
Acros Organics	AC269230250	https://www.fishersci.com/shop/products/potassium-diphosphate-98-extra-pure-acros-organics-1/AC269230250
AK Scientific, Inc. (AKSCI)	5408AF	http://www.aksci.com/item_detail.php?cat=5408AF
Alfa Chemistry	10124-52-4	https://www.alfa-chemistry.com/cas_10124-52-4.htm
Alfa Chemistry	7320-34-5	https://www.alfa-chemistry.com/potassium-pyrophosphate-cas-7320-34-5-item-222405.htm
Alfa Chemistry	ACM7320345	https://materials.alfachemic.com/potassium-pyrophosphate-cas-7320-34-5-item-222405.htm
Angene	AGN-PC-0U2JU5	http://www.angenechemical.com/productshow/AGN-PC-0U2JU5.html
Aurora Fine Chemicals LLC	A17.900.800	http://online.aurorafinechemicals.com/info?ID=A17.900.800
Avantor Inc	101183-582	https://us.vwr.com/store/catalog/product.jsp?catalog_number=101183-582
Avantor Inc	BT220330-1KG	https://us.vwr.com/store/product/16639977/tetrapotassium-diphosphate-anhydrous-96
Avantor Inc	BT220330-5KG	https://us.vwr.com/store/product/16639977/tetrapotassium-diphosphate-anhydrous-96
BioChemPartner	BCP25976	http://www.biochempartner.com/7320-34-5-BCP25976
BioSynth	J-524026	https://www.biosynth.com/en/products/all-products/products/J-524026.html
BLD Pharm	BD148772	http://www.bldpharm.com/products/7320-34-5.html
BOC Sciences	7320-34-5	https://www.bocsci.com/potassium-pyrophosphate-cas-7320-34-5-item-97685.html
ChemMol	49412314	http://www.chemmol.com/chemmol/49412314.html
ChemMol	99151493	http://www.chemmol.com/chemmol/99151493.html
eNovation Chemicals	D627910	https://www.enovationchem.com/ProductDetails.asp?ProductID=D627910
Finetech	FT-0710299	http://www.finetechnology-ind.com/prod/detail/pub/7320-34-5.html
Glentham Life Sciences	GK4932	http://www.glentham.com/products/product/GK4932/
Hairui	HR131311	http://www.hairuichem.com/en/product/7320-34-5.html
MolPort	MolPort-006-118-632	https://www.molport.com/shop/molecule-link/MolPort-006-118-632
MuseChem	M015126	https://www.musechem.com/product/M015126.html
MuseChem	M122724	https://www.musechem.com/product/M122724.html
Oakwood	97627	http://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=135141&ExtHyperLink=1
Parchem	17482	http://www.parchem.com/chemical-supplier-distributor/potassium-pyrophosphate-007482.aspx
Parchem	25057	http://www.parchem.com/chemical-supplier-distributor/Tetrapotassium-Pyrophosphate-015057.aspx
Renno Tech	RL04782	http://www.rennotech.com/product_show.asp?id=5031
Sinfoo Biotech	S051964	http://www.sinfoobiotech.com/product/1055362
Smolecule	S603405	https://www.smolecule.com/products/s603405
THE BioTek	bt-295912	https://www.thebiotek.com/product/others/bt-295912
VladaChem	VL143983	https://www.vladachem.com/product.php?products=7320-34-5
VladaChem	VL164566	https://www.vladachem.com/product.php?products=7320-34-5

PubMed

Title	Date	PubMed
Practical application of bioluminescence enzyme immunoassay using enhancer for firefly luciferin-luciferase bioluminescence.	2009-08-22	21681909
Synthesis of triclinic calcium pyrophosphate crystals.	2007-07	17277979
Adenosine monophosphate-induced amplification of ColE1 plasmid DNA in Escherichia coli.	2007-05	17134753
Influence of inorganic pyrophosphate on the kinetics of muscle pyruvate kinase: a simple nonallosteric feedback model.	2002-09-03	12204438

Patents

Sample Use Guides

In Vivo Use Guide

DENTRIFICE CONTAINING 5% SODIUM AND POTASSIUM PYROPHOSPHATE WAS ADVISED TWICE DAILY FOR 6 MONTHS

Route of Administration: Dental

In Vitro Use Guide

To determine foscarnet in calf and human serums, extraction was performed with an anion exchanger, SAX, from which the analyte was eluted with a 50 mM potassium pyrophosphate buffer, pH 8.4.

Name

Type

Language

TETRAPOTASSIUM PYROPHOSPHATE

Preferred Name

English

POTASSIUM PYROPHOSPHATE

Systematic Name

English

TETRA POTASSIUM PYROPHOSPHATE

Systematic Name

English

POTASSIUM PYROPHOSPHATE [MI]

Common Name

English

DIPHOSPHORIC ACID TETRAPOTASSIUM SALT

Common Name

English

POTASSIUM PYROPHOSPHATE [FCC]

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 173.315