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Details

Stereochemistry RACEMIC
Molecular Formula C20H26N2S.ClH
Molecular Weight 362.96
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETYMEMAZINE HYDROCHLORIDE

SMILES

Cl.CCC1=CC2=C(SC3=C(C=CC=C3)N2CC(C)CN(C)C)C=C1

InChI

InChIKey=ZVSKDFRXWJPINY-UHFFFAOYSA-N
InChI=1S/C20H26N2S.ClH/c1-5-16-10-11-20-18(12-16)22(14-15(2)13-21(3)4)17-8-6-7-9-19(17)23-20;/h6-12,15H,5,13-14H2,1-4H3;1H

HIDE SMILES / InChI

Description

Etymemazine (RP-6484), a phenothiazine derivative, is a sedative and neuroleptic agent. It is a histamine H₁-receptor antagonist. It was used to treat dementia. It was also used in veterinary.

Originator

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
[Clinical study of a new phenothiazine derivative, RP-6484].
1960 Jun 11
[On the clinical use in neuropsychiatry of 3-ethyl-10-(2-methyl-3-dimethylaminopropyl)-phenothiazine HCl (RP-6484), new phenothiazine neuroleptic].
1962 Jun 2
[DEMENTIA PRAECOX. CURE BY RP-6484].
1963 Dec

Sample Use Guides

In Vivo Use Guide
Pigs: Ethyl isobutrazine (Etymemazine) and pethidine were each administered at a dose rate of 5 mg/kg
Route of Administration: Intramuscular
Name Type Language
ETYMEMAZINE HYDROCHLORIDE
MI  
Common Name English
10-(3-(DIMETHYLAMINO)-2-METHYLPROPYL)-2-ETHYLPHENOTHIAZINE HYDROCHLORIDE
Systematic Name English
ETHYLISOBUTRAZINE HYDROCHLORIDE
Common Name English
PHENOTHIAZINE, 10-(3-(DIMETHYLAMINO)-2-METHYLPROPYL)-2-ETHYL-, MONOHYDROCHLORIDE
Common Name English
(±)-ETYMEMAZINE HYDROCHLORIDE
Common Name English
NSC-169471
Code English
ETYMEMAZINE HCL
Common Name English
RP 6484
Code English
ETYMEMAZINE HYDROCHLORIDE, (±)-
Common Name English
ETHYMEMAZINE MONOHYDROCHLORIDE
Common Name English
RP-6484
Code English
10H-PHENOTHIAZINE-10-PROPANAMINE, 2-ETHYL-N,N,.BETA.-TRIMETHYL-,HYDROCHLORIDE (1:1)
Common Name English
ETYMEMAZINE HYDROCHLORIDE [GREEN BOOK]
Common Name English
SERGETYL
Brand Name English
NUITAL
Brand Name English
ETYMEMAZINE HYDROCHLORIDE [MI]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29578
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
Code System Code Type Description
NSC
169471
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
PRIMARY
ChEMBL
CHEMBL2008544
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
PRIMARY
PUBCHEM
71822
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
PRIMARY
MERCK INDEX
m728
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
PRIMARY Merck Index
CAS
3737-33-5
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
PRIMARY
EPA CompTox
DTXSID1045110
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
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FDA UNII
A7002E7T2Z
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
PRIMARY
DRUG BANK
DBSALT001681
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
PRIMARY
NCI_THESAURUS
C81141
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
PRIMARY
ECHA (EC/EINECS)
223-111-8
Created by admin on Fri Dec 15 16:06:47 GMT 2023 , Edited by admin on Fri Dec 15 16:06:47 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of ETYMEMAZINE
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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