Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C17H23N5O4 |
| Molecular Weight | 361.3956 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC(=N)C1=CC=C(C=C1)N2C[C@@H](CN3CCN(CC(O)=O)CC3)OC2=O
InChI
InChIKey=BXTGCIBGRDGLNI-CQSZACIVSA-N
InChI=1S/C17H23N5O4/c18-16(19)12-1-3-13(4-2-12)22-10-14(26-17(22)25)9-20-5-7-21(8-6-20)11-15(23)24/h1-4,14H,5-11H2,(H3,18,19)(H,23,24)/t14-/m1/s1
Gantofiban (or EMD 122 347) is an oral double prodrug of the drug, EMD 132338 and is GPIIb/IIIa antagonist. The drug participated in phase II clinical trials in Japan in patients with thrombosis. However, in May 2004, Yamanouchi, the developing company, announced that the study was discontinued. Besides gantofiban was involved in phase II trials, like a treatment option in patients with the acute coronary syndrome. However, further information is not available.
Originator
Approval Year
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9950809
Created by
admin on Wed Apr 02 17:23:35 GMT 2025 , Edited by admin on Wed Apr 02 17:23:35 GMT 2025
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PRIMARY | |||
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9Y2SN3W6A3
Created by
admin on Wed Apr 02 17:23:35 GMT 2025 , Edited by admin on Wed Apr 02 17:23:35 GMT 2025
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167364-01-4
Created by
admin on Wed Apr 02 17:23:35 GMT 2025 , Edited by admin on Wed Apr 02 17:23:35 GMT 2025
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PRIMARY |
ACTIVE MOIETY
PRODRUG (METABOLITE ACTIVE)