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Details

Stereochemistry ACHIRAL
Molecular Formula C11H8BrO4.Na
Molecular Weight 307.073
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of SODIUM BROMEBRATE

SMILES

[Na+].COC1=CC=C(C=C1)C(=O)C(\Br)=C/C([O-])=O

InChI

InChIKey=DVDCIQWIGOVWEX-MLBSPLJJSA-M
InChI=1S/C11H9BrO4.Na/c1-16-8-4-2-7(3-5-8)11(15)9(12)6-10(13)14;/h2-6H,1H3,(H,13,14);/q;+1/p-1/b9-6+;

HIDE SMILES / InChI

Description

Bromebric Acid (Cytembena) is a derivative of bromoacrylic acid with cytostatic and antineoplastic activity. Chemical structure of Bromebric Acid is not related to any previous antineoplastic agent. In animal tumor screens, Jelinek and Semonsky noted antineoplastic activity of Cytembena against sarcoma 180, atlenocarcinoina of the lactic gland in mice, Ehrlich’s ascitic carcinoma, Yoshida’s ascitic sarcoma, and Zojdeln’s heap

Originator

Approval Year

PubMed