Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H6O3S |
| Molecular Weight | 110.132 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COS(=O)OC
InChI
InChIKey=BDUPRNVPXOHWIL-UHFFFAOYSA-N
InChI=1S/C2H6O3S/c1-4-6(3)5-2/h1-2H3
Dimethyl sulfate (DMS) is a diester of methanol and sulfurous acid. Dimethyl sulfate is a potential reagent for the methylation. It is a substrate for sulfite oxidase. Dimethyl sulfate is stable in blood and can be transported from the intestines to the alveoli and the air. Therefore, DMS in the blood is accepted as a marker of halitosis. The high DMS levels in systemic circulation detected in the multicenter case-control clinical study of laryngopharyngeal reflux.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: 1.07055408E8 Gene Symbol: SUOX Sources: https://www.ncbi.nlm.nih.gov/pubmed/8519792 |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Diagnostic | Unknown Approved UseUnknown |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Laryngopharyngeal Reflux Has Negative Effects on Taste and Smell Functions. | 2016-07 |
|
| [Effect of design and operation parameters on volatile alkylsulfides removal in subsurface constructed wetlands]. | 2010-02 |
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| A tale of two oxidation states: bacterial colonization of arsenic-rich environments. | 2007-04-13 |
|
| Matrix isolation FTIR spectroscopic and theoretical study of dimethyl sulfite. | 2005-04-28 |
|
| Derivatisation in gas chromatographic determination of acidic herbicides in aqueous environmental samples. | 2003-10 |
|
| Oxoanionic or sulfur lone pair attack? The difference in reactivity of hydrogensulfite anion and neutral dimethylsulfite towards [Bu4N]2[MoO2(S2C2)CN)2)2] in the model reductive half reaction of sulfite oxidase. | 2001-09-21 |
|
| The reaction of chicken liver sulfite oxidase with dimethylsulfite. | 1995-12-06 |
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| Analysis of the possible altering function of the septal organ in rats: a lesional and behavioral study. | 1995-11 |
|
| Impairment of olfactory perception in male rats by treatment with p-chlorophenylalanine and hydrocortisone. | 1978 |
Patents
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Preferred Name | English | ||
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69223
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C097173
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210-481-0
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616-42-2
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48858
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100000172753
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41902
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9JFA40S66P
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DTXSID3060665
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DIMETHYL SULFITE
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SUBSTANCE RECORD