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Details

Stereochemistry RACEMIC
Molecular Formula C12H18N2O3S
Molecular Weight 270.348
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ARTICAINE ACID

SMILES

CCCNC(C)C(=O)NC1=C(SC=C1C)C(O)=O

InChI

InChIKey=LUPKINKNYDFRIB-UHFFFAOYSA-N
InChI=1S/C12H18N2O3S/c1-4-5-13-8(3)11(15)14-9-7(2)6-18-10(9)12(16)17/h6,8,13H,4-5H2,1-3H3,(H,14,15)(H,16,17)

HIDE SMILES / InChI
Articaine, a dental local anesthetic, is metabolized into articaine acid. The last is excreted as such or further transforms into the glucuronidated metabolite.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: UDP-glucuronosyltransferase
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Pharmacokinetics, metabolism, and renal excretion of articaine and its metabolite articainic acid in patients after epidural administration.
1989 Jan
A simple method for the determination of articaine and its metabolite articainic acid in dentistry: application to a comparison of articaine and lidocaine concentrations in alveolus blood.
1993 Oct
Clinical pharmacology and the use of articaine for local and regional anaesthesia.
2005 Jun

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
ARTICAINE ACID
Common Name English
2-THIOPHENECARBOXYLIC ACID, 4-METHYL-3-((1-OXO-2-(PROPYLAMINO)PROPYL)AMINO)-
Common Name English
ARTICAINIC ACID
Common Name English
ARTICAINE RELATED COMPOUND B
USP-RS  
Common Name English
ARTICAINE HYDROCHLORIDE IMPURITY B [EP IMPURITY]
Common Name English
4-METHYL-3-(((2RS)-2-(PROPYLAMINO)PROPANOYL)AMINO)THIOPHENE-2-CARBOXYLIC ACID
Systematic Name English
ARTICAINE RELATED COMPOUND B [USP-RS]
Common Name English
Code System Code Type Description
PUBCHEM
163921
Created by admin on Fri Dec 15 15:33:33 GMT 2023 , Edited by admin on Fri Dec 15 15:33:33 GMT 2023
PRIMARY
RS_ITEM_NUM
1042930
Created by admin on Fri Dec 15 15:33:33 GMT 2023 , Edited by admin on Fri Dec 15 15:33:33 GMT 2023
PRIMARY
CAS
114176-52-2
Created by admin on Fri Dec 15 15:33:33 GMT 2023 , Edited by admin on Fri Dec 15 15:33:33 GMT 2023
PRIMARY
EPA CompTox
DTXSID50921296
Created by admin on Fri Dec 15 15:33:33 GMT 2023 , Edited by admin on Fri Dec 15 15:33:33 GMT 2023
PRIMARY
FDA UNII
99R4WP7QC7
Created by admin on Fri Dec 15 15:33:33 GMT 2023 , Edited by admin on Fri Dec 15 15:33:33 GMT 2023
PRIMARY