Details
Stereochemistry | RACEMIC |
Molecular Formula | C12H18N2O3S |
Molecular Weight | 270.348 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCNC(C)C(=O)NC1=C(SC=C1C)C(O)=O
InChI
InChIKey=LUPKINKNYDFRIB-UHFFFAOYSA-N
InChI=1S/C12H18N2O3S/c1-4-5-13-8(3)11(15)14-9-7(2)6-18-10(9)12(16)17/h6,8,13H,4-5H2,1-3H3,(H,14,15)(H,16,17)
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/15966499
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15966499
Articaine, a dental local anesthetic, is metabolized into articaine acid. The last is excreted as such or further transforms into the glucuronidated metabolite.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: UDP-glucuronosyltransferase Sources: https://www.ncbi.nlm.nih.gov/pubmed/15966499 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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PubMed
Title | Date | PubMed |
---|---|---|
Pharmacokinetics, metabolism, and renal excretion of articaine and its metabolite articainic acid in patients after epidural administration. | 1989 Jan |
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A simple method for the determination of articaine and its metabolite articainic acid in dentistry: application to a comparison of articaine and lidocaine concentrations in alveolus blood. | 1993 Oct |
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Clinical pharmacology and the use of articaine for local and regional anaesthesia. | 2005 Jun |
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163921
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1042930
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114176-52-2
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DTXSID50921296
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99R4WP7QC7
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PARENT (METABOLITE)
SUBSTANCE RECORD