| Stereochemistry | RACEMIC |
| Molecular Formula | C13H11N3OS |
| Molecular Weight | 257.311 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[O-][S+](CC1=CC=CC=N1)C2=NC3=CC=CC=C3N2
InChI
InChIKey=HBDKFZNDMVLSHM-UHFFFAOYSA-N
InChI=1S/C13H11N3OS/c17-18(9-10-5-3-4-8-14-10)13-15-11-6-1-2-7-12(11)16-13/h1-8H,9H2,(H,15,16)
Timoprazole is a substituted benzimidazole patented by Aktiebolag Hassle as an antisecretory agent that inhibits gastric acid secretion by interference with (H+-K+)-ATPase. Timoprazole given orally was found to be cytoprotective for the stomach when given 30 min prior to a challenge to boiling water, ethanol, or HCl. Timoprazole also prevented necrosis of the mucosa and acute ulcerations induced by alcohol in the rat fundus, as evaluated by histopathology.
Originator
Approval Year
PubMed
Patents
ACTIVE MOIETY
