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Details

Stereochemistry RACEMIC
Molecular Formula C27H31NO3.ClH
Molecular Weight 454.001
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ASOCAINOL HYDROCHLORIDE

SMILES

Cl.COC1=CC2=C(CCN(C)C(CCC3=CC=CC=C3)CC4=C2C(O)=C(OC)C=C4)C=C1

InChI

InChIKey=JTGDTQLVMHZOHX-UHFFFAOYSA-N
InChI=1S/C27H31NO3.ClH/c1-28-16-15-20-10-13-23(30-2)18-24(20)26-21(11-14-25(31-3)27(26)29)17-22(28)12-9-19-7-5-4-6-8-19;/h4-8,10-11,13-14,18,22,29H,9,12,15-17H2,1-3H3;1H

HIDE SMILES / InChI
Asocainol is a rather efficient antiarrhythmic agent that has the effects of both class Ia and class IV antiarrhythmic drugs. Asocainol interfere with the sodium channel and lengthens the action potential. Besides that, Asocainol decreases conduction through the AV node, and shorten phase two (the plateau) of the cardiac action potential. Asocainol reduce the contractility of the heart, so may be inappropriate in heart failure. Asocainol is an effective antiarrhythmic agent in a variety of animal arrhythmia models and species.

Approval Year

PubMed

PubMed

TitleDatePubMed
Asocainol, a new antiarrhythmic drug with natrium- and calcium-antagonistic effects on ventricular myocardium.
1984-11-01
Patents

Patents

Name Type Language
ASOCAINOL HYDROCHLORIDE
Common Name English
5H-DIBENZ(D,F)AZONIN-1-OL, 6,7,8,9-TETRAHYDRO-2,12-DIMETHOXY-7-METHYL-6-(2-PHENYLETHYL)-, HYDROCHLORIDE (1:1)
Preferred Name English
Code System Code Type Description
ECHA (EC/EINECS)
293-842-5
Created by admin on Mon Mar 31 22:43:09 GMT 2025 , Edited by admin on Mon Mar 31 22:43:09 GMT 2025
PRIMARY
FDA UNII
8VX5A020BS
Created by admin on Mon Mar 31 22:43:09 GMT 2025 , Edited by admin on Mon Mar 31 22:43:09 GMT 2025
PRIMARY
PUBCHEM
170357
Created by admin on Mon Mar 31 22:43:09 GMT 2025 , Edited by admin on Mon Mar 31 22:43:09 GMT 2025
PRIMARY
CAS
91574-89-9
Created by admin on Mon Mar 31 22:43:09 GMT 2025 , Edited by admin on Mon Mar 31 22:43:09 GMT 2025
PRIMARY
EPA CompTox
DTXSID40919647
Created by admin on Mon Mar 31 22:43:09 GMT 2025 , Edited by admin on Mon Mar 31 22:43:09 GMT 2025
PRIMARY