Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C27H31NO3 |
| Molecular Weight | 417.5399 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC2=C(CCN(C)C(CCC3=CC=CC=C3)CC4=CC=C(OC)C(O)=C24)C=C1
InChI
InChIKey=IORHSKBXWWSQME-UHFFFAOYSA-N
InChI=1S/C27H31NO3/c1-28-16-15-20-10-13-23(30-2)18-24(20)26-21(11-14-25(31-3)27(26)29)17-22(28)12-9-19-7-5-4-6-8-19/h4-8,10-11,13-14,18,22,29H,9,12,15-17H2,1-3H3
| Molecular Formula | C27H31NO3 |
| Molecular Weight | 417.5399 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Asocainol is a rather efficient antiarrhythmic agent that has the effects of both class Ia and class IV antiarrhythmic drugs. Asocainol interfere with the sodium channel and lengthens the action potential. Besides that, Asocainol decreases conduction through the AV node, and shorten phase two (the plateau) of the cardiac action potential. Asocainol reduce the contractility of the heart, so may be inappropriate in heart failure. Asocainol is an effective antiarrhythmic agent in a variety of animal arrhythmia models and species.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:57:23 GMT 2023
by
admin
on
Fri Dec 15 16:57:23 GMT 2023
|
| Record UNII |
J40338OKKT
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Official Name | English | ||
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Common Name | English | ||
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Systematic Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C47793
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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5092
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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PRIMARY | |||
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SUB05583MIG
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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PRIMARY | |||
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C042287
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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PRIMARY | |||
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C72574
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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PRIMARY | |||
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CHEMBL2104050
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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PRIMARY | |||
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ASOCAINOL
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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PRIMARY | |||
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J40338OKKT
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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PRIMARY | |||
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77400-65-8
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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PRIMARY | |||
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71161
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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PRIMARY | |||
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100000086608
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
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PRIMARY | |||
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DTXSID90868434
Created by
admin on Fri Dec 15 16:57:23 GMT 2023 , Edited by admin on Fri Dec 15 16:57:23 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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|
ENANTIOMER -> RACEMATE | |||
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|
ENANTIOMER -> RACEMATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
