ASOCAINOL

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C27H31NO3
Molecular Weight	417.5399
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

COC1=CC2=C(CCN(C)C(CCC3=CC=CC=C3)CC4=CC=C(OC)C(O)=C24)C=C1

InChI

InChIKey=IORHSKBXWWSQME-UHFFFAOYSA-N

InChI=1S/C27H31NO3/c1-28-16-15-20-10-13-23(30-2)18-24(20)26-21(11-14-25(31-3)27(26)29)17-22(28)12-9-19-7-5-4-6-8-19/h4-8,10-11,13-14,18,22,29H,9,12,15-17H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C27H31NO3
Molecular Weight	417.5399
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description

Asocainol is a rather efficient antiarrhythmic agent that has the effects of both class Ia and class IV antiarrhythmic drugs. Asocainol interfere with the sodium channel and lengthens the action potential. Besides that, Asocainol decreases conduction through the AV node, and shorten phase two (the plateau) of the cardiac action potential. Asocainol reduce the contractility of the heart, so may be inappropriate in heart failure. Asocainol is an effective antiarrhythmic agent in a variety of animal arrhythmia models and species.