Details
Stereochemistry | RACEMIC |
Molecular Formula | C27H31NO3.ClH |
Molecular Weight | 454.001 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.COC1=CC2=C(CCN(C)C(CCC3=CC=CC=C3)CC4=CC=C(OC)C(O)=C24)C=C1
InChI
InChIKey=JTGDTQLVMHZOHX-UHFFFAOYSA-N
InChI=1S/C27H31NO3.ClH/c1-28-16-15-20-10-13-23(30-2)18-24(20)26-21(11-14-25(31-3)27(26)29)17-22(28)12-9-19-7-5-4-6-8-19;/h4-8,10-11,13-14,18,22,29H,9,12,15-17H2,1-3H3;1H
Molecular Formula | C27H31NO3 |
Molecular Weight | 417.5399 |
Charge | 0 |
Count |
|
Stereochemistry | RACEMIC |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Optical Activity | ( + / - ) |
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Asocainol is a rather efficient antiarrhythmic agent that has the effects of both class Ia and class IV antiarrhythmic drugs. Asocainol interfere with the sodium channel and lengthens the action potential. Besides that, Asocainol decreases conduction through the AV node, and shorten phase two (the plateau) of the cardiac action potential. Asocainol reduce the contractility of the heart, so may be inappropriate in heart failure. Asocainol is an effective antiarrhythmic agent in a variety of animal arrhythmia models and species.
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:33:12 GMT 2023
by
admin
on
Sat Dec 16 09:33:12 GMT 2023
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Record UNII |
8VX5A020BS
|
Record Status |
Validated (UNII)
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Record Version |
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-
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293-842-5
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8VX5A020BS
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admin on Sat Dec 16 09:33:12 GMT 2023 , Edited by admin on Sat Dec 16 09:33:12 GMT 2023
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170357
Created by
admin on Sat Dec 16 09:33:12 GMT 2023 , Edited by admin on Sat Dec 16 09:33:12 GMT 2023
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91574-89-9
Created by
admin on Sat Dec 16 09:33:12 GMT 2023 , Edited by admin on Sat Dec 16 09:33:12 GMT 2023
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DTXSID40919647
Created by
admin on Sat Dec 16 09:33:12 GMT 2023 , Edited by admin on Sat Dec 16 09:33:12 GMT 2023
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Related Record | Type | Details | ||
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ENANTIOMER -> RACEMATE | |||
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ENANTIOMER -> RACEMATE |
Related Record | Type | Details | ||
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ACTIVE MOIETY |