U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C16H22ClN3O
Molecular Weight 307.818
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLETOQUINE

SMILES

CC(CCCNCCO)NC1=CC=NC2=C1C=CC(Cl)=C2

InChI

InChIKey=XFICNUNWUREFDP-UHFFFAOYSA-N
InChI=1S/C16H22ClN3O/c1-12(3-2-7-18-9-10-21)20-15-6-8-19-16-11-13(17)4-5-14(15)16/h4-6,8,11-12,18,21H,2-3,7,9-10H2,1H3,(H,19,20)

HIDE SMILES / InChI
Cletoquine is a metabolite of a disease-modifying anti-rheumatic and antimalarial drug hydroxychloroquine. It is produced by oxidative N-deethylation of hydroxychloroquine.

Approval Year

PubMed

PubMed

TitleDatePubMed
Identification and characterization of process related impurities in chloroquine and hydroxychloroquine by LC/IT/MS, LC/TOF/MS and NMR.
2009 May 1
Name Type Language
CLETOQUINE
INN  
INN  
Official Name English
cletoquine [INN]
Common Name English
DESETHYLHYDROXYCHLOROQUINE
Common Name English
GNF-PF-1952
Code English
2-((4-((7-CHLORO-4-QUINOLYL)AMINO)PENTYL)AMINO)ETHANOL
Systematic Name English
(±)-DESETHYLHYDROXYCHLOROQUINE
Common Name English
HYDROXYCHLOROQUINE SULFATE IMPURITY C [EP IMPURITY]
Common Name English
2-((4-((7-CHLOROQUINOLIN-4-YL)AMINO)PENTYL)AMINO)ETHAN-1-OL
Systematic Name English
Code System Code Type Description
INN
2583
Created by admin on Sat Dec 16 17:07:14 GMT 2023 , Edited by admin on Sat Dec 16 17:07:14 GMT 2023
PRIMARY
NCI_THESAURUS
C79524
Created by admin on Sat Dec 16 17:07:14 GMT 2023 , Edited by admin on Sat Dec 16 17:07:14 GMT 2023
PRIMARY
SMS_ID
100000080195
Created by admin on Sat Dec 16 17:07:14 GMT 2023 , Edited by admin on Sat Dec 16 17:07:14 GMT 2023
PRIMARY
EVMPD
SUB06654MIG
Created by admin on Sat Dec 16 17:07:14 GMT 2023 , Edited by admin on Sat Dec 16 17:07:14 GMT 2023
PRIMARY
CAS
4298-15-1
Created by admin on Sat Dec 16 17:07:14 GMT 2023 , Edited by admin on Sat Dec 16 17:07:14 GMT 2023
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PUBCHEM
71826
Created by admin on Sat Dec 16 17:07:14 GMT 2023 , Edited by admin on Sat Dec 16 17:07:14 GMT 2023
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EPA CompTox
DTXSID70863361
Created by admin on Sat Dec 16 17:07:14 GMT 2023 , Edited by admin on Sat Dec 16 17:07:14 GMT 2023
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FDA UNII
83CVD213TU
Created by admin on Sat Dec 16 17:07:14 GMT 2023 , Edited by admin on Sat Dec 16 17:07:14 GMT 2023
PRIMARY
ChEMBL
CHEMBL580132
Created by admin on Sat Dec 16 17:07:14 GMT 2023 , Edited by admin on Sat Dec 16 17:07:14 GMT 2023
PRIMARY