LEVOXADROL

C1OC(O[C@@H]1[C@H]2CCCCN2)(C3=CC=CC=C3)C4=CC=CC=C4

InChIKey=HGKAMARNFGKMLC-MOPGFXCFSA-N

InChI=1S/C20H23NO2/c1-3-9-16(10-4-1)20(17-11-5-2-6-12-17)22-15-19(23-20)18-13-7-8-14-21-18/h1-6,9-12,18-19,21H,7-8,13-15H2/t18-,19+/m1/s1

Levoxadrol is an active enantiomer of dexoxadrol.

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Phencyclidine binds to blood platelets with high affinity and specifically inhibits their activation by adrenaline.	1992-07-01	1322125
Interaction of phencyclidine with voltage-dependent potassium channels in cultured rat hippocampal neurons: comparison with block of the NMDA receptor-ionophore complex.	1989-11	2555461
Comparison of the effects of the acute administration of dexoxadrol, levoxadrol, MK-801 and phencyclidine on body temperature in the rat.	1989-08	2674766
Psychotomimetic sigma-ligands, dexoxadrol and phencyclidine block the same presynaptic potassium channel in rat brain.	1988-09	3253423
Coexpression of N-methyl-D-aspartate and phencyclidine receptors in Xenopus oocytes injected with rat brain mRNA.	1988-05	2834739
Effects of phencyclidine, SKF 10,047 and related psychotomimetic agents on N-methyl-D-aspartate receptor mediated synaptic responses in rat hippocampal slices.	1987-07	3038243
Characterization of specific sigma opiate/phencyclidine (PCP)-binding sites in the human brain.	1983	6319873
Stereospecific binding of 3H-phencyclidine in brain membranes.	1982-06-21	7109842

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Name

Type

Language

LEVOXADROL

Official Name

English

PIPERIDINE, 2-((4R)-2,2-DIPHENYL-1,3-DIOXOLAN-4-YL)-, (2R)-

Preferred Name

English

levoxadrol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C241