Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C15H15N3O.C3H6O3 |
| Molecular Weight | 343.377 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(O)C(O)=O.CCOC1=CC2=C(C=C1)N=C3C=C(N)C=CC3=C2N
InChI
InChIKey=IYLLULUTZPKQBW-UHFFFAOYSA-N
InChI=1S/C15H15N3O.C3H6O3/c1-2-19-10-4-6-13-12(8-10)15(17)11-5-3-9(16)7-14(11)18-13;1-2(4)3(5)6/h3-8H,2,16H2,1H3,(H2,17,18);2,4H,1H3,(H,5,6)
DescriptionCurator's Comment: description was created based on several sources, including, www.ncbi.nlm.nih.gov/pubmed/17294498, http://www.chemaxpharma.com/en/rivanol-chemax-pharma-0-1
Curator's Comment: description was created based on several sources, including, www.ncbi.nlm.nih.gov/pubmed/17294498, http://www.chemaxpharma.com/en/rivanol-chemax-pharma-0-1
Ethacridine (Rivanol) is an acridine derivative indicated for the treatment of bacterial infections. In many countries the drug was in clinical practice for the second trimester termination of pregnancy.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Community coalitions and prevention: a panel discussion. | 2004 Aug |
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| The relationship between protein sequences and their gene ontology functions. | 2006 Dec 12 |
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| Myocardial performance in conscious streptozotocin diabetic rats. | 2006 Dec 4 |
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| Protein and overtraining: potential applications for free-living athletes. | 2006 Jun 5 |
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| The association between indwelling urinary catheter use in the elderly and urinary tract infection in acute care. | 2006 Oct 12 |
|
| L5-S1 laparoscopic anterior interbody fusion. | 2006 Oct-Dec |
|
| Effects of tamoxifen on vaginal blood flow and epithelial morphology in the rat. | 2006 Sep 13 |
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| Substance abuse prevention infrastructure: a survey-based study of the organizational structure and function of the D.A.R.E. program. | 2006 Sep 6 |
|
| Construct validity of the endoscopic sinus surgery simulator: II. Assessment of discriminant validity and expert benchmarking. | 2007 Apr |
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| Silent rupture of unscarred uterus: an unusual presentation at second trimester abortion. | 2007 Apr |
|
| Genomic and expression analysis of multiple Sry loci from a single Rattus norvegicus Y chromosome. | 2007 Apr 4 |
|
| Genetic mapping of a new heart rate QTL on chromosome 8 of spontaneously hypertensive rats. | 2007 Apr 9 |
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| Phylogenetic review of tonal sound production in whales in relation to sociality. | 2007 Aug 10 |
|
| Sry delivery to the adrenal medulla increases blood pressure and adrenal medullary tyrosine hydroxylase of normotensive WKY rats. | 2007 Feb 26 |
|
| [Value of estrogen for preventing postpartum hemorrhage and shortening birth process in induce abortion]. | 2007 Jan |
|
| Sex differences in judging self-orientation: the morphological horizon and body pitch. | 2007 Jan 7 |
|
| Left-sided gallbladder (sinistroposition) with duplication of the common bile duct. | 2007 Jan-Mar |
|
| Physiologically-based testing system for the mechanical characterization of prosthetic vein valves. | 2007 Jul 13 |
|
| Stimulation of MAP kinase pathways after maternal IL-1beta exposure induces fetal lung fluid absorption in guinea pigs. | 2007 Mar 26 |
|
| Outcomes of decompression for lumbar spinal canal stenosis based upon preoperative radiographic severity. | 2007 Mar 8 |
|
| An HPLC method for the determination of ethacridine lactate in human urine. | 2007 May |
|
| Baseline characteristics influencing quality of life in women undergoing gynecologic oncology surgery. | 2007 May 17 |
|
| A cell culture model using rat coronary artery adventitial fibroblasts to measure collagen production. | 2007 May 8 |
|
| Is mechanism of injury alone in the prehospital setting a predictor of major trauma - a review of the literature. | 2007 Nov 26 |
|
| Nodal signaling is required for closure of the anterior neural tube in zebrafish. | 2007 Nov 8 |
|
| Modeling and detection of respiratory-related outbreak signatures. | 2007 Oct 5 |
|
| A laparoscopic simulator tool for objective measurement of residents' laparoscopic ability. | 2007 Oct-Dec |
|
| Effects of interpregnancy interval and outcome of the preceding pregnancy on pregnancy outcomes in Matlab, Bangladesh. | 2007 Sep |
|
| Double blind, randomized, placebo controlled clinical trial for the treatment of diabetic foot ulcers, using a nitric oxide releasing patch: PATHON. | 2007 Sep 26 |
|
| The organizational effects of oxytocin on the central expression of estrogen receptor alpha and oxytocin in adulthood. | 2007 Sep 7 |
|
| Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration. | 2008 |
|
| Anticancer Activity of Ag(I) N-Heterocyclic Carbene Complexes Derived from 4,5-Dichloro-1H-Imidazole. | 2008 |
|
| The Cuyahoga is still burning. | 2008 Apr |
|
| Strain-specific virulence phenotypes of Streptococcus pneumoniae assessed using the Chinchilla laniger model of otitis media. | 2008 Apr 9 |
|
| Molecular epidemiology of A/H3N2 and A/H1N1 influenza virus during a single epidemic season in the United States. | 2008 Aug 22 |
|
| Effects of the selective serotonin reuptake inhibitor fluoxetine on counterregulatory responses to hypoglycemia in individuals with type 1 diabetes. | 2008 Dec |
|
| Antibiotics and antiseptics for venous leg ulcers. | 2008 Jan 23 |
|
| The Akron dome midfoot osteotomy as a salvage procedure for the treatment of rigid pes cavus: a retrospective review. | 2008 Jan-Feb |
|
| Mixtures of quaternary ammonium compounds and anionic organic compounds in the aquatic environment: Elimination and biodegradability in the closed bottle test monitored by LC-MS/MS. | 2008 Jun |
|
| A 12 week, open label, phase I/IIa study using apatone for the treatment of prostate cancer patients who have failed standard therapy. | 2008 Mar 24 |
|
| Testosterone influences renal electrolyte excretion in SHR/y and WKY males. | 2008 Mar 26 |
|
| Misoprostol preferable to ethacridine lactate for abortions at 13-20 weeks of pregnancy: Cuban experience. | 2008 May |
|
| Second trimester abortions in India. | 2008 May |
|
| Brisk walking compared with an individualised medical fitness programme for patients with type 2 diabetes: a randomised controlled trial. | 2008 May |
|
| Sticky gecko feet: the role of temperature and humidity. | 2008 May 14 |
|
| Role of central nervous system glucagon-like Peptide-1 receptors in enteric glucose sensing. | 2008 Oct |
|
| Effects of a selective serotonin reuptake inhibitor, fluoxetine, on counterregulatory responses to hypoglycemia in healthy individuals. | 2008 Sep |
|
| Genomics, molecular imaging, bioinformatics, and bio-nano-info integration are synergistic components of translational medicine and personalized healthcare research. | 2008 Sep 16 |
|
| The design, development, and evaluation of a prototypic, prosthetic venous valve. | 2008 Sep 19 |
|
| Hemodialysis vascular access options in pediatrics: considerations for patients and practitioners. | 2009 Jun |
Sample Use Guides
Apply 0,1 % cutaneous solution to the affected area of skin.
Route of Administration:
Topical
In Vitro Use Guide
Sources: DOI: 10.1159/isbn.978-3-318-00780-0, DOI: 10.1159/isbn.978-3-318-00780-0, Retrived from https://books.google.es/books?id=JkQOSAnOIhoC&pg=PA99&lpg=PA99&dq=ETHACRIDINE+mic&source=bl&ots=ghsA6y1h9Q&sig=6zSd_yIDEu9rFqfcJOX9sWPt_SA&hl=ru&sa=X&ved=0ahUKEwjbvvvK5u7OAhVKnRQKHWRQAzMQ6AEIJTAB#v=onepage&q=ETHACRIDINE%20mic&f=false
Ethacridine shows weak becteriostatic activity against gram-positive bacteria with MIC 1-10 ug/ml.
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15789
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217-408-1
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100000087298
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36333
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1837-57-6
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DTXSID10872472
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7T7T2I9823
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ACTIVE MOIETY
SUBSTANCE RECORD
