ETHACRIDINE LACTATE ANHYDROUS

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H15N3O.C3H6O3
Molecular Weight	343.377
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ETHACRIDINE LACTATE ANHYDROUS

SMILES

CC(O)C(O)=O.CCOC1=CC2=C(C=C1)N=C3C=C(N)C=CC3=C2N

InChI

InChIKey=IYLLULUTZPKQBW-UHFFFAOYSA-N

InChI=1S/C15H15N3O.C3H6O3/c1-2-19-10-4-6-13-12(8-10)15(17)11-5-3-9(16)7-14(11)18-13;1-2(4)3(5)6/h3-8H,2,16H2,1H3,(H2,17,18);2,4H,1H3,(H,5,6)

HIDE SMILES / InChI

Description

Ethacridine (Rivanol) is an acridine derivative indicated for the treatment of bacterial infections. In many countries the drug was in clinical practice for the second trimester termination of pregnancy.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Bacterial infections	Curative		Approved	RIVANOL

Doses

Doses

Show entries

Dose	Population	Adverse events
200 mL single, intrauterine Recommended	pregnant, ADULT

Showing 1 to 1 of 1 entries

Previous1Next

PubMed

Show entries

Title	Date	PubMed
Method for non-invasively recording electrocardiograms in conscious mice.	2001	11476671
Ohio hospitals and nursing homes improve care coordination.	2003 Oct	14650980
Retrospective comparison of nebulized levalbuterol and albuterol for adverse events in patients with acute airflow obstruction.	2003 Sep-Oct	12975718
Blood samples drawn from IV catheters have less hemolysis when 5-mL (vs 10-mL) collection tubes are used.	2004 Dec	15565033
[Spectral analysis of the electrical activity of the left colon].	2004 Jul-Sep	15678202

Showing 1 to 5 of 23 entries

Previous1 2 3 4 5Next

Patents

Sample Use Guides

In Vivo Use Guide

Apply 0,1 % cutaneous solution to the affected area of skin.

Route of Administration: Topical

In Vitro Use Guide

Ethacridine shows weak becteriostatic activity against gram-positive bacteria with MIC 1-10 ug/ml.

Show entries

Name

Type

Language

ETHACRIDINE LACTATE ANHYDROUS

Common Name

English

NSC-36333

Code

English

6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE

Systematic Name

English

PROPANOIC ACID, 2-HYDROXY-, COMPD. WITH 7-ETHOXY-3,9-ACRIDINEDIAMINE (1:1)

Common Name

English

ETHACRIDINE LACTATE ANHYDROUS, (±)-

Common Name

English

Showing 1 to 5 of 7 entries

Previous1 2Next

Show entries

Code System

Code

Type

Description

PUBCHEM

15789

PRIMARY

ECHA (EC/EINECS)

217-408-1

PRIMARY

SMS_ID

100000087298

PRIMARY

NSC

36333

PRIMARY

CAS

1837-57-6

PRIMARY

Showing 1 to 5 of 7 entries

Previous1 2Next

ACTIVE MOIETY


					WIX85M1A6R

ETHACRIDINE

SUBSTANCE RECORD


					7T7T2I9823

ETHACRIDINE LACTATE ANHYDROUS