MEDIBAZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C25H26N2O2
Molecular Weight	386.4861
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C(N1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC5=C(OCO5)C=C4

InChI

InChIKey=ORAUEDBBTFLQSK-UHFFFAOYSA-N

InChI=1S/C25H26N2O2/c1-3-7-21(8-4-1)25(22-9-5-2-6-10-22)27-15-13-26(14-16-27)18-20-11-12-23-24(17-20)29-19-28-23/h1-12,17,25H,13-16,18-19H2

HIDE SMILES / InChI

Description
Sources: https://books.google.ru/books?id=iFnsCAAAQBAJ&printsec=frontcover&hl=ru#v=onepage&q&f=false | https://www.drugfuture.com/chemdata/Medibazine.html | https://www.ncbi.nlm.nih.gov/pubmed/4866140

Medibazine (Vialibran) is a piperazine derivative. Medibazine is a coronary vasodilating agent. Although several non-controlled trials report favorable results with angina patients this medication certainly does not provide any outstanding results.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
smooth muscle contraction 13 Target ID: GO:0006939 Sources: https://link.springer.com/book/10.1007/978-1-4757-2085-3#about \| https://www.drugfuture.com/chemdata/Medibazine.html	Inhibitor 8297

PubMed

Title	Date	PubMed
[Cardiac anti-arrhythmic effect of various N-substituted piperazine derivatives with respect to aconitine in the rat].	1979	158405

Patents

Name

Type

Language

MEDIBAZINE

Official Name

English

S-4105

Code

English

1-BENZHYDRYL-4-PIPERONYLPIPERAZINE

Common Name

English

1-(1,3-BENZODIOXOL-5-YLMETHYL)-4-(DIPHENYLMETHYL)PIPERAZINE

Common Name

English

PIPERAZINE, 1-(1,3-BENZODIOXOL-5-YLMETHYL)-4-(DIPHENYLMETHYL)-

Systematic Name

English

medibazine [INN]

Common Name

English

MEDIBAZINE [MI]

Common Name

English

S4105

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29578