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Details

Stereochemistry ACHIRAL
Molecular Formula C25H26N2O2.2ClH
Molecular Weight 459.408
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEDIBAZINE DIHYDROCHLORIDE

SMILES

Cl.Cl.C(N1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC5=C(OCO5)C=C4

InChI

InChIKey=NABGGBAFLGQEJP-UHFFFAOYSA-N
InChI=1S/C25H26N2O2.2ClH/c1-3-7-21(8-4-1)25(22-9-5-2-6-10-22)27-15-13-26(14-16-27)18-20-11-12-23-24(17-20)29-19-28-23;;/h1-12,17,25H,13-16,18-19H2;2*1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C25H26N2O2
Molecular Weight 386.4861
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Medibazine (Vialibran) is a piperazine derivative. Medibazine is a coronary vasodilating agent. Although several non-controlled trials report favorable results with angina patients this medication certainly does not provide any outstanding results.

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
PubMed

PubMed

TitleDatePubMed
Angina drug trial: a comparison of the clinical use of vialibran and iproveratril.
1967 Nov 25
[Cardiac anti-arrhythmic effect of various N-substituted piperazine derivatives with respect to aconitine in the rat].
1979
Patents

Patents

US3119826
3
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:06:15 GMT 2023
Edited
by admin
on Sat Dec 16 08:06:15 GMT 2023
Record UNII
6NRF3LXS7J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MEDIBAZINE DIHYDROCHLORIDE
Common Name English
VIALIBRAN
Brand Name English
PIPERAZINE, 1-(1,3-BENZODIOXOL-5-YLMETHYL)-4-(DIPHENYLMETHYL)-, HYDROCHLORIDE (1:2)
Systematic Name English
MEDIBAZINE DIHYDROCHLORIDE [MI]
Common Name English
Code System Code Type Description
PUBCHEM
13861295
Created by admin on Sat Dec 16 08:06:15 GMT 2023 , Edited by admin on Sat Dec 16 08:06:15 GMT 2023
PRIMARY
MERCK INDEX
m301
Created by admin on Sat Dec 16 08:06:15 GMT 2023 , Edited by admin on Sat Dec 16 08:06:15 GMT 2023
PRIMARY
CAS
96588-03-3
Created by admin on Sat Dec 16 08:06:15 GMT 2023 , Edited by admin on Sat Dec 16 08:06:15 GMT 2023
PRIMARY
FDA UNII
6NRF3LXS7J
Created by admin on Sat Dec 16 08:06:15 GMT 2023 , Edited by admin on Sat Dec 16 08:06:15 GMT 2023
PRIMARY
Related Record Type Details
Structure of MEDIBAZINE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of MEDIBAZINE
ACTIVE MOIETY
NIH
NCATS
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