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Details

Stereochemistry ACHIRAL
Molecular Formula C25H26N2O2.ClH
Molecular Weight 422.947
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEDIBAZINE HYDROCHLORIDE

SMILES

Cl.C(N1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC5=C(OCO5)C=C4

InChI

InChIKey=BYVBJMSCDWLDRN-UHFFFAOYSA-N
InChI=1S/C25H26N2O2.ClH/c1-3-7-21(8-4-1)25(22-9-5-2-6-10-22)27-15-13-26(14-16-27)18-20-11-12-23-24(17-20)29-19-28-23;/h1-12,17,25H,13-16,18-19H2;1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C25H26N2O2
Molecular Weight 386.4861
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Medibazine (Vialibran) is a piperazine derivative. Medibazine is a coronary vasodilating agent. Although several non-controlled trials report favorable results with angina patients this medication certainly does not provide any outstanding results.

Approval Year

Unknown
149124
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8504
PubMed

PubMed

TitleDatePubMed
[Cardiac anti-arrhythmic effect of various N-substituted piperazine derivatives with respect to aconitine in the rat].
1979
Angina drug trial: a comparison of the clinical use of vialibran and iproveratril.
1967-11-25
Patents

Patents

US3119826
3
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:01:53 GMT 2025
Edited
by admin
on Mon Mar 31 18:01:53 GMT 2025
Record UNII
10F3RUK41T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MEDIBAZINE HYDROCHLORIDE
Common Name English
PIPERAZINE, 1-(1,3-BENZODIOXOL-5-YLMETHYL)-4-(DIPHENYLMETHYL)-, HYDROCHLORIDE (1:1)
Preferred Name English
Code System Code Type Description
CAS
22193-78-8
Created by admin on Mon Mar 31 18:01:53 GMT 2025 , Edited by admin on Mon Mar 31 18:01:53 GMT 2025
PRIMARY
FDA UNII
10F3RUK41T
Created by admin on Mon Mar 31 18:01:53 GMT 2025 , Edited by admin on Mon Mar 31 18:01:53 GMT 2025
PRIMARY
PUBCHEM
23619732
Created by admin on Mon Mar 31 18:01:53 GMT 2025 , Edited by admin on Mon Mar 31 18:01:53 GMT 2025
PRIMARY PUBCHEM
Related Record Type Details
Structure of MEDIBAZINE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of MEDIBAZINE
ACTIVE MOIETY
NIH
NCATS
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