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Details

Stereochemistry RACEMIC
Molecular Formula C19H19N.HNO3
Molecular Weight 324.3737
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Phenindamine Nitrate

SMILES

O[N+]([O-])=O.CN1CCC2=C(C1)C(C3=CC=CC=C23)C4=CC=CC=C4

InChI

InChIKey=VNPBUNUBQYZEKS-UHFFFAOYSA-N
InChI=1S/C19H19N.HNO3/c1-20-12-11-16-15-9-5-6-10-17(15)19(18(16)13-20)14-7-3-2-4-8-14;2-1(3)4/h2-10,19H,11-13H2,1H3;(H,2,3,4)

HIDE SMILES / InChI

Description
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/18907211

Phenindamine (thephorin or 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1-pyridindene) a pyridindene derivative proved to be a potent antihistaminic. Phenindamine was used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
THEPHORIN

Approved Use

Phenindamine was used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Launch Date

1947
PubMed

PubMed

TitleDatePubMed
The effects of phenindamine tartrate on sleepiness and psychomotor performance.
1992 Dec
Patents

Patents

Sample Use Guides

The maximum amount of phenindamine that you should take in 1 day is 75 mg.
Route of Administration: Other
In Vitro Use Guide
Unknown
Name Type Language
Phenindamine Nitrate
Common Name English
1H-Indeno[2,1-c]pyridine, 2,3,4,9-tetrahydro-2-methyl-9-phenyl-, nitrate
Systematic Name English
1H-Indeno[2,1-c]pyridine, 2,3,4,9-tetrahydro-2-methyl-9-phenyl-, nitrate (1:1)
Systematic Name English
2-methyl-9-phenyl-1,3,4,9-tetrahydroindeno[2,1-c]pyridine,nitricacid
Systematic Name English
Code System Code Type Description
PUBCHEM
71338160
Created by admin on Sat Dec 16 19:55:21 GMT 2023 , Edited by admin on Sat Dec 16 19:55:21 GMT 2023
PRIMARY
CAS
114226-44-7
Created by admin on Sat Dec 16 19:55:21 GMT 2023 , Edited by admin on Sat Dec 16 19:55:21 GMT 2023
PRIMARY
FDA UNII
7EXK7X55BR
Created by admin on Sat Dec 16 19:55:21 GMT 2023 , Edited by admin on Sat Dec 16 19:55:21 GMT 2023
PRIMARY