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Details

Stereochemistry RACEMIC
Molecular Formula C19H19N.HNO3
Molecular Weight 324.3737
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Phenindamine Nitrate

SMILES

O[N+]([O-])=O.CN1CCC2=C(C1)C(C3=CC=CC=C23)C4=CC=CC=C4

InChI

InChIKey=VNPBUNUBQYZEKS-UHFFFAOYSA-N
InChI=1S/C19H19N.HNO3/c1-20-12-11-16-15-9-5-6-10-17(15)19(18(16)13-20)14-7-3-2-4-8-14;2-1(3)4/h2-10,19H,11-13H2,1H3;(H,2,3,4)

HIDE SMILES / InChI

Molecular Formula C19H19N
Molecular Weight 261.3609
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Molecular Formula HNO3
Molecular Weight 63.0128
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Phenindamine (thephorin or 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1-pyridindene) a pyridindene derivative proved to be a potent antihistaminic. Phenindamine was used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

CNS Activity

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
THEPHORIN

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
The maximum amount of phenindamine that you should take in 1 day is 75 mg.
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
7EXK7X55BR
Record Status Validated (UNII)
Record Version