LY-2979165

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C13H17N5O5S
Molecular Weight	355.37
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@](C[C@H]2SC3=NN=CN3)(NC(=O)[C@H](C)N)C(O)=O

InChI

InChIKey=BBGHHIUQOKQCBW-LDZWZCGGSA-N

InChI=1S/C13H17N5O5S/c1-4(14)9(19)17-13(11(22)23)2-5(24-12-15-3-16-18-12)6-7(8(6)13)10(20)21/h3-8H,2,14H2,1H3,(H,17,19)(H,20,21)(H,22,23)(H,15,16,18)/t4-,5+,6-,7-,8-,13-/m0/s1

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Metabotropic glutamate receptor 2 24 Target ID: CHEMBL5137 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29564482 \| https://adisinsight.springer.com/drugs/800033329	Agonist 2678
Metabotropic glutamate receptor 3 16 Target ID: CHEMBL2888 Sources: https://adisinsight.springer.com/drugs/800033329	Agonist 2678

PubMed

Title	Date	PubMed
Evaluation of single and multiple doses of a novel mGlu2 agonist, a potential antipsychotic therapy, in healthy subjects.	2017 Aug	28156011

Name

Type

Language

LY-2979165

Code

English

HY-13239

Code

English

BICYCLO(3.1.0)HEXANE-2,6-DICARBOXYLIC ACID, 2-(((2S)-2-AMINO-1-OXOPROPYL)AMINO)-4-(1H-1,2,4-TRIAZOL-5-YLTHIO)-, (1R,2S,4R,5R,6R)-

Systematic Name

English

Code System Code Type Description

ChEMBL

CHEMBL3544939