LY-2979165 AMMONIUM MONOHYDRATE

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C13H17N5O5S.H2O.H3N
Molecular Weight	390.415
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LY-2979165 AMMONIUM MONOHYDRATE

Structure Search

SMILES

N.O.C[C@H](N)C(=O)N[C@]1(C[C@@H](SC2=NN=CN2)[C@H]3[C@@H]([C@@H]13)C(O)=O)C(O)=O

InChI

InChIKey=FICWTZOQUXUYOK-AHKKVLALSA-N

InChI=1S/C13H17N5O5S.H3N.H2O/c1-4(14)9(19)17-13(11(22)23)2-5(24-12-15-3-16-18-12)6-7(8(6)13)10(20)21;;/h3-8H,2,14H2,1H3,(H,17,19)(H,20,21)(H,22,23)(H,15,16,18);1H3;1H2/t4-,5+,6-,7-,8-,13-;;/m0../s1

HIDE SMILES / InChI

Molecular Formula	C13H17N5O5S
Molecular Weight	355.37
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H3N
Molecular Weight	17.0305
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Metabotropic glutamate receptor 2 24 Target ID: CHEMBL5137 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29564482 \| https://adisinsight.springer.com/drugs/800033329	Agonist 2752
Metabotropic glutamate receptor 3 16 Target ID: CHEMBL2888 Sources: https://adisinsight.springer.com/drugs/800033329	Agonist 2752

PubMed

Title	Date	PubMed
Group II metabotropic glutamate receptor agonist prodrugs LY2979165 and LY2140023 attenuate the functional imaging response to ketamine in healthy subjects.	2018-07	29564482
Evaluation of single and multiple doses of a novel mGlu2 agonist, a potential antipsychotic therapy, in healthy subjects.	2017-08	28156011

Substance Class	Chemical Created by `admin` on `Tue Apr 01 21:32:57 GMT 2025` Edited by `admin` on `Tue Apr 01 21:32:57 GMT 2025`
Record UNII	04MW5TZ18S
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BICYCLO(3.1.0)HEXANE-2,6-DICARBOXYLIC ACID, 2-(((2S)-2-AMINO-1-OXOPROPYL)AMINO)-4-(1H-1,2,4-TRIAZOL-5-YLTHIO)-, AMMONIUM SALT, HYDRATE (1:1:1), (1R,2S,4R,5R,6R)-

Preferred Name

English

LY-2979165 AMMONIUM MONOHYDRATE

Code

English

Code System Code Type Description

PUBCHEM

66577008

Created by admin on Tue Apr 01 21:32:57 GMT 2025 , Edited by admin on Tue Apr 01 21:32:57 GMT 2025

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FDA UNII

04MW5TZ18S

Created by admin on Tue Apr 01 21:32:57 GMT 2025 , Edited by admin on Tue Apr 01 21:32:57 GMT 2025

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CAS

1311385-32-6

Created by admin on Tue Apr 01 21:32:57 GMT 2025 , Edited by admin on Tue Apr 01 21:32:57 GMT 2025

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EPA CompTox

DTXSID00735345

Created by admin on Tue Apr 01 21:32:57 GMT 2025 , Edited by admin on Tue Apr 01 21:32:57 GMT 2025

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