LY-2979165 AMMONIUM MONOHYDRATE

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C13H17N5O5S.H2O.H3N
Molecular Weight	390.415
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LY-2979165 AMMONIUM MONOHYDRATE

Structure Search

SMILES

N.O.[H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@](C[C@H]2SC3=NN=CN3)(NC(=O)[C@H](C)N)C(O)=O

InChI

InChIKey=FICWTZOQUXUYOK-AHKKVLALSA-N

InChI=1S/C13H17N5O5S.H3N.H2O/c1-4(14)9(19)17-13(11(22)23)2-5(24-12-15-3-16-18-12)6-7(8(6)13)10(20)21;;/h3-8H,2,14H2,1H3,(H,17,19)(H,20,21)(H,22,23)(H,15,16,18);1H3;1H2/t4-,5+,6-,7-,8-,13-;;/m0../s1

HIDE SMILES / InChI

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H3N
Molecular Weight	17.0305
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C13H17N5O5S
Molecular Weight	355.37
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Metabotropic glutamate receptor 2 24 Target ID: CHEMBL5137 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29564482 \| https://adisinsight.springer.com/drugs/800033329	Agonist 2678
Metabotropic glutamate receptor 3 16 Target ID: CHEMBL2888 Sources: https://adisinsight.springer.com/drugs/800033329	Agonist 2678

PubMed

Title	Date	PubMed
Evaluation of single and multiple doses of a novel mGlu2 agonist, a potential antipsychotic therapy, in healthy subjects.	2017 Aug	28156011
Group II metabotropic glutamate receptor agonist prodrugs LY2979165 and LY2140023 attenuate the functional imaging response to ketamine in healthy subjects.	2018 Jul	29564482

Substance Class	Chemical Created by `admin` on `Sat Dec 16 13:53:17 GMT 2023` Edited by `admin` on `Sat Dec 16 13:53:17 GMT 2023`
Record UNII	04MW5TZ18S
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

LY-2979165 AMMONIUM MONOHYDRATE

Code

English

BICYCLO(3.1.0)HEXANE-2,6-DICARBOXYLIC ACID, 2-(((2S)-2-AMINO-1-OXOPROPYL)AMINO)-4-(1H-1,2,4-TRIAZOL-5-YLTHIO)-, AMMONIUM SALT, HYDRATE (1:1:1), (1R,2S,4R,5R,6R)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

66577008

Created by admin on Sat Dec 16 13:53:18 GMT 2023 , Edited by admin on Sat Dec 16 13:53:18 GMT 2023

PRIMARY

FDA UNII

04MW5TZ18S

Created by admin on Sat Dec 16 13:53:18 GMT 2023 , Edited by admin on Sat Dec 16 13:53:18 GMT 2023

PRIMARY

CAS

1311385-32-6

Created by admin on Sat Dec 16 13:53:18 GMT 2023 , Edited by admin on Sat Dec 16 13:53:18 GMT 2023

PRIMARY

EPA CompTox

DTXSID00735345

Created by admin on Sat Dec 16 13:53:18 GMT 2023 , Edited by admin on Sat Dec 16 13:53:18 GMT 2023

PRIMARY

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LY-2979165

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