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Details

Stereochemistry ACHIRAL
Molecular Formula C21H27N3O3.ClH
Molecular Weight 405.918
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ANIDOXIME HYDROCHLORIDE

SMILES

Cl.CCN(CC)CCC(=NOC(=O)NC1=CC=C(OC)C=C1)C2=CC=CC=C2

InChI

InChIKey=BXYLCIMGDIDYPP-UHFFFAOYSA-N
InChI=1S/C21H27N3O3.ClH/c1-4-24(5-2)16-15-20(17-9-7-6-8-10-17)23-27-21(25)22-18-11-13-19(26-3)14-12-18;/h6-14H,4-5,15-16H2,1-3H3,(H,22,25);1H

HIDE SMILES / InChI

Description

Anidoxime is unrelated to other analgesic agents in clinical use. It is the hydrochloride salt of 0-(4-methoxyphenyl-carboxyl)-3-diethylamino-propiophenone oxime, with an empirical formula C21H27N3O3 HCl. It was in clinical trial as an oral analgesic agent.

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Comparative analgesic, behavioral, and dependence properties of morphine and O-(4-methoxylphenylcarbamoyl)-3-diethylaminopropiophenone oxime hydrochloride.
1980-02
Anidoxime: a clinical trial of an oral analgesic agent.
1977-03
Patents

Patents

EP2255184A2
2

Sample Use Guides

In Vivo Use Guide
The new oral analgesic drug anidoxime was compared with dihydrocodeine. There were no side-effects, and no significant differences between the effects of dihydrocodeine 50 mg, anidoxime 75 mg or anidoxime 100 mg.
Route of Administration: Oral
Name Type Language
1-PROPANONE, 3-(DIETHYLAMINO)-1-PHENYL-, O-(((4-METHOXYPHENYL)AMINO)CARBONYL)OXIME, MONOHYDROCHLORIDE
Preferred Name English
ANIDOXIME HYDROCHLORIDE
Common Name English
O-(4-METHOXYPHENYLCARBAMOYL)-3-DIETHYLAMINOPROPIOPHENONE OXIME HYDROCHLORIDE
Systematic Name English
Code System Code Type Description
CAS
31729-11-0
Created by admin on Mon Mar 31 18:09:41 GMT 2025 , Edited by admin on Mon Mar 31 18:09:41 GMT 2025
PRIMARY
FDA UNII
70QM1XR26G
Created by admin on Mon Mar 31 18:09:41 GMT 2025 , Edited by admin on Mon Mar 31 18:09:41 GMT 2025
PRIMARY
PUBCHEM
35883
Created by admin on Mon Mar 31 18:09:41 GMT 2025 , Edited by admin on Mon Mar 31 18:09:41 GMT 2025
PRIMARY
PARENT (SALT/SOLVATE)
Structure of ANIDOXIME
NIH
NCATS
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