GAROMEFRINE HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H13FN2O3S.ClH
Molecular Weight	284.735
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CS(=O)(=O)NC1=CC([C@@H](O)CN)=C(F)C=C1

InChI

InChIKey=NYBZUGIMUSJVGU-FVGYRXGTSA-N

InChI=1S/C9H13FN2O3S.ClH/c1-16(14,15)12-6-2-3-8(10)7(4-6)9(13)5-11;/h2-4,9,12-13H,5,11H2,1H3;1H/t9-;/m0./s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8719417 | https://adisinsight.springer.com/drugs/800005693

Garomefrine (NS-49) is a partial agonist of 1a-adrenoreceptor, selective with respect to other alpha 1 adrenoreceptors. It was developed by Nippon Shinyaku and investigated in clinical trials for the treatment of urinary incontinence in Japan, Europe, and the USA.

Approval Year

Name

Type

Language

GAROMEFRINE HYDROCHLORIDE

Common Name

English

ABT-232

Preferred Name

English

METHANESULFONAMIDE, N-(3-((1R)-2-AMINO-1-HYDROXYETHYL)-4-FLUOROPHENYL)-, MONOHYDROCHLORIDE

Common Name

English

GAROMEFRIN HYDROCHLORIDE, (-)-

Common Name

English

GAROMEFRIN MONOHYDROCHLORIDE

Common Name

English

(-)-GAROMEFRIN HYDROCHLORIDE

Common Name

English

PNO-49B

Common Name

English

METHANESULFONAMIDE, N-(3-(2-AMINO-1-HYDROXYETHYL)-4-FLUOROPHENYL)-, MONOHYDROCHLORIDE, (R)-

Common Name

English

((R)-(-)-3'-(2-AMINO-1-HYDROXYETHYL)-4'-FLUORO-METHANESULFONANILIDE HYDROCHLORIDE

Common Name

English

METHANESULFONAMIDE, N-(3-((1R)-2-AMINO-1-HYDROXYETHYL)-4-FLUOROPHENYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

GAROMEFRINE HYDROCHLORIDE [JAN]

Common Name

English

NS-49

Common Name

English

Code System Code Type Description

CHEBI

167680