2,6-XYLIDINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H11N.ClH
Molecular Weight	157.641
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC1=CC=CC(C)=C1N

InChI

InChIKey=QNWMFJDRMZWZNN-UHFFFAOYSA-N

InChI=1S/C8H11N.ClH/c1-6-4-3-5-7(2)8(6)9;/h3-5H,9H2,1-2H3;1H

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Hepatic effects of xylidine isomers in rats.	1979 Jan	224531
Synthesis, characterization, and comparative 32P-postlabeling efficiencies of 2,6-dimethylaniline-DNA adducts.	2001 Feb	11258965
Lack of DNA binding in the rat nasal mucosa and other tissues of the nasal toxicants roflumilast, a phosphodiesterase 4 inhibitor, and a metabolite, 4-amino-3,5-dichloropyridine, in contrast to the nasal carcinogen 2,6-dimethylaniline.	2002 Feb	11850974
Involvement of liver carboxylesterases in the in vitro metabolism of lidocaine.	2002 Jun	12019189
Asymmetric synthesis of axially chiral benzamides and anilides by enantiotopic lithiation of prochiral arene chromium complexes.	2002 Mar 22	11895413
The effect of deuterium and fluorine substitution upon the mutagenicity of N-hydroxy-2,6-dimethylaniline.	2002 Sep 30	12351143
Determination of 2,6-dimethylaniline and o-toluidine impurities in preparations for local anaesthesia by the HPLC method with amperometric detection.	2002 Sep-Oct	12602793
Update on olfactory mucosal metabolic enzymes: age-related changes and N-acetyltransferase activities.	2004	15452881
Primary amido substituted diborane4 compounds and imidodiborate4 anions.	2005 Oct 7	16172634
DNA adduct formation by 2,6-dimethyl-, 3,5-dimethyl-, and 3-ethylaniline in vivo in mice.	2006 Aug	16918249
Changes in production of lignin degrading enzymes during interactions between mycelia of the tropical decomposer basidiomycetes Marasmiellus troyanus and Marasmius pallescens.	2006 Feb	16488366
In vitro metabolism and interactions of the fungicide metalaxyl in human liver preparations.	2007 Jan	21783735
N-(2,6-Dimethyl-phen-yl)benzene-sulfonamide.	2008 Aug 6	21201680
Quantitative mass spectrometric analysis of ropivacaine and bupivacaine in authentic, pharmaceutical and spiked human plasma without chromatographic separation.	2008 May 28	19652756
2,6-Dimethyl-anilinium chloride monohydrate.	2008 Nov 29	21581431
N-(2,6-Dimethyl-phen-yl)succinamic acid.	2009 Feb 6	21582137
Kinetics of 2,6-dimethylaniline degradation by electro-Fenton process.	2009 Jan 30	18554787
Ethyl 2-[(2,6-dimethyl-phen-yl)hydrazono]-3-oxobutanoate.	2009 Jun 10	21582829
N-[3-(2,6-Dimethylanilino)-1-methylbut-2-enylidene]-2,6-dimethylanilinium chloride.	2009 Jun 24	21582931
N-(2,6-Dimethyl-phen-yl)-2-(2-thien-yl)acetamide.	2009 Nov 25	21578912
Iron-catalyzed dehydrogenative phosphonation of N,N-dimethylanilines.	2009 Oct 28	19809631
Separation and analysis of dimethylaniline isomers by supercritical fluid chromatography--electrospray ionization tandem mass spectrometry.	2009 Oct 9	19733358
N-(2,6-Dimethyl-phen-yl)-4-methyl-benzene-sulfonamide.	2010 Apr 24	21579210
N-(2,6-Dimethyl-phen-yl)succinimide.	2010 Jan 9	21579755
Third-order nonlinear optical properties and structures of (E)-N-(4-nitrobenzylidene)-2,6-dimethylaniline and (E)-N-(4-nitrobenzylidene)-2,3-dimethylaniline.	2010 May	20194047

Patents

Name

Type

Language

2,6-XYLIDINE HYDROCHLORIDE

Systematic Name

English

ROPIVACAINE RELATED COMPOUND A [USP-RS]

Common Name

English

BENZENAMINE, 2,6-DIMETHYL-, HYDROCHLORIDE (1:1)

Systematic Name

English

LIDOCAINE HYDROCHLORIDE RELATED COMPOUND 2,6-DIMETHYLANILINE HYDROCHLORIDE [USP IMPURITY]

Common Name

English

2,6-DIMETHYLANILINE HYDROCHLORIDE

Systematic Name

English

BENZENAMINE, 2,6-DIMETHYL-, HYDROCHLORIDE

Systematic Name

English

ROPIVACAINE RELATED COMPOUND A [USP IMPURITY]

Common Name

English

ROPIVACAINE RELATED COMPOUND A

Common Name

English

2,6-XYLIDINE, HYDROCHLORIDE

Systematic Name

English

2,6-DIMETHYLBENZENAMINE HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

CAS

21436-98-6