MPTP HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H15N.ClH
Molecular Weight	209.715
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

Cl.CN1CCC(=CC1)C2=CC=CC=C2

InChI

InChIKey=KOWJANGMTAZWDT-UHFFFAOYSA-N

InChI=1S/C12H15N.ClH/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11;/h2-7H,8-10H2,1H3;1H

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Amine oxidase [flavin-containing] B 11	Substrate 661
Mitochondrial complex I (NADH dehydrogenase) 11	Inhibitor 8,297
Amine oxidase [flavin-containing] B 11	Inhibitor 8,297

PubMed

PubMed

Show entries

Title	Date	PubMed
The alpha2-adrenergic receptor antagonist idazoxan reduces dyskinesia and enhances anti-parkinsonian actions of L-dopa in the MPTP-lesioned primate model of Parkinson's disease.	1999 Sep	10495035
Investigating levodopa-induced dyskinesias in the parkinsonian primate.	2000 Apr	10762135
AMPA receptor blockade improves levodopa-induced dyskinesia in MPTP monkeys.	2000 Apr 25	10762498
Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model.	2000 May	10830409
GDNF reverses priming for dyskinesia in MPTP-treated, L-DOPA-primed common marmosets.	2001 Feb	11168568

Showing 1 to 5 of 15 entries

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Name

Type

Language

MPTP HYDROCHLORIDE

Common Name

English

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE

Systematic Name

English

PYRIDINE, 1,2,3,6-TETRAHYDRO-1-METHYL-4-PHENYL-, HYDROCHLORIDE (1:1)

Systematic Name

English

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Code System

Code

Type

Description

FDA UNII

5O1K9K2EZM

PRIMARY

WIKIPEDIA

MPTP hydrochloride

PRIMARY

CAS

23007-85-4

PRIMARY

PUBCHEM

161406

PRIMARY

EPA CompTox

DTXSID5044077

PRIMARY

Showing 1 to 5 of 5 entries

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PARENT (SALT/SOLVATE)


					9P21XSP91P

MPTP

SUBSTANCE RECORD


					5O1K9K2EZM

MPTP HYDROCHLORIDE