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Details

Stereochemistry RACEMIC
Molecular Formula C16H16ClNO3
Molecular Weight 305.756
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLOFEVERINE

SMILES

OC1=CC2=C(C=C1O)C(COC3=CC=C(Cl)C=C3)NCC2

InChI

InChIKey=GVALVWDQPXGPCE-UHFFFAOYSA-N
InChI=1S/C16H16ClNO3/c17-11-1-3-12(4-2-11)21-9-14-13-8-16(20)15(19)7-10(13)5-6-18-14/h1-4,7-8,14,18-20H,5-6,9H2

HIDE SMILES / InChI

Description

Clofeverine is a compound synthesized by the Japanese company Fujisawa Pharmaceutical. Clofeverine is a highly selective relaxant for gastrointestinal smooth muscles with a beta-receptor stimulative nature. On isolated ileum, the inhibitory effect of clofeverine for spontaneous motility was comparable to that of isoproterenol and 100 times higher than that of papaverine.

Approval Year