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Details

Stereochemistry RACEMIC
Molecular Formula C19H25N2OS
Molecular Weight 329.48
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of PROMETHAZINE HYDROXYETHYL

SMILES

CC(CN1C2=C(SC3=C1C=CC=C3)C=CC=C2)[N+](C)(C)CCO

InChI

InChIKey=PDSVTRQOBUIQBQ-UHFFFAOYSA-N
InChI=1S/C19H25N2OS/c1-15(21(2,3)12-13-22)14-20-16-8-4-6-10-18(16)23-19-11-7-5-9-17(19)20/h4-11,15,22H,12-14H2,1-3H3/q+1

HIDE SMILES / InChI

Description

Promethazine hydroxyethyl quaternary derivative of promethazine with antihistamine and anticholinergic properties. The drug lacked the sedative properties of promethazine. It was used in the clinic under tradename Aprobit.

Approval Year

Unknown
139594
Name Type Language
PROMETHAZINE HYDROXYETHYL
Common Name English
N-HYDROXYETHYLPROMETHAZINE
Common Name English
HYDROXYETHYLPROMETHAZINE
Common Name English
10H-PHENOTHIAZINE-10-ETHANAMINIUM, N-(2-HYDROXYETHYL)-N,N,.ALPHA.-TRIMETHYL-
Systematic Name English
AMMONIUM, (2-HYDROXYETHYL)DIMETHYL(1-METHYL-2-PHENOTHIAZIN-10-YLETHYL)-
Systematic Name English
Classification Tree Code System Code
WHO-ATC R06AD55
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
WHO-VATC QR06AD55
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
WHO-ATC R06AD05
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID30871861
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
PRIMARY
DRUG CENTRAL
4571
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
PRIMARY
FDA UNII
571559SLAJ
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
PRIMARY
PUBCHEM
16406
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
PRIMARY
DRUG BANK
DB13840
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
PRIMARY
WIKIPEDIA
Hydroxyethylpromethazine
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
PRIMARY
CAS
7647-63-4
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
PRIMARY
ChEMBL
CHEMBL3707371
Created by admin on Sat Dec 16 10:44:09 GMT 2023 , Edited by admin on Sat Dec 16 10:44:09 GMT 2023
PRIMARY
NIH
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