U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2C6H5O7.2Ca.Fe
Molecular Weight 514.2
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERROUS CALCIUM CITRATE

SMILES

[Ca++].[Ca++].[Fe++].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

InChIKey=HSBFYEQJGSVAJW-UHFFFAOYSA-H
InChI=1S/2C6H8O7.2Ca.Fe/c2*7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h2*13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;;3*+2/p-6

HIDE SMILES / InChI
Iron(II) gluconate (also known as a ferrous gluconate) is used in the treatment of hypochromic anemia. The real problem of iron therapy is not the theoretical utilization of iron, or the reticulocyte response, or even the daily increase of hemoglobin. These are important only as they indicate the return of the patients' blood to normal in a reasonably short time without undue inconvenience. Most patients suffering from hypochromic anemia respond well to most forms of iron when administered in adequate dosage. For the patients who cannot tolerate the usual iron compounds, it is important to have a medication which is effective and which causes minimum disturbance. Ferrous gluconate is such a medicament.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Primary
Ferro Sanol Duodenal

Approved Use

Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
PubMed

PubMed

TitleDatePubMed
FERROUS IODIDE AND LINOLEIC ACID IN VITAMIN A DEFICIENCY. A REPLY TO CERTAIN CRITICISMS.
1932 Nov 11
THE USE OF FERROUS GLUCONATE IN THE TREATMENT OF HYPOCHROMIC ANEMIA.
1937 Jul
Clinical appraisal of drugs with special reference to a new chelate hematinic.
1957 Jul 11
[FERROUS ASPARTATE IN THERAPY].
1964 Jan 1
Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis.
2007
Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice.
2009
The effect of iron treatment on adhesion molecules in patients with iron deficiency anemia.
2010 Dec
Tolerability of different oral iron supplements: a systematic review.
2013 Apr
A practical and successful desensitization protocol for immediate hypersensitivity reactions to iron salts.
2014
Patents

Sample Use Guides

Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
FERROUS CALCIUM CITRATE
Common Name English
CALCIUM FERROUS CITRATE [MI]
Common Name English
RARICAL
Brand Name English
FERROCAL
Brand Name English
DICALCIUM IRON(2+) BIS(2-HYDROXYPROPANE-1,2,3-TRICARBOXYLATE)
Systematic Name English
Calcium ferrous citrate [WHO-DD]
Common Name English
CALCIUM FERROUS CITRATE
MART.   WHO-DD  
Common Name English
CALCIUM FERROUS CITRATE [MART.]
Common Name English
Code System Code Type Description
EVMPD
SUB130515
Created by admin on Fri Dec 15 15:31:52 GMT 2023 , Edited by admin on Fri Dec 15 15:31:52 GMT 2023
PRIMARY
EVMPD
SUB13173MIG
Created by admin on Fri Dec 15 15:31:52 GMT 2023 , Edited by admin on Fri Dec 15 15:31:52 GMT 2023
PRIMARY
CAS
7600-56-8
Created by admin on Fri Dec 15 15:31:52 GMT 2023 , Edited by admin on Fri Dec 15 15:31:52 GMT 2023
NON-SPECIFIC STOICHIOMETRY
FDA UNII
4P1IZU59M5
Created by admin on Fri Dec 15 15:31:52 GMT 2023 , Edited by admin on Fri Dec 15 15:31:52 GMT 2023
PRIMARY
EPA CompTox
DTXSID60226906
Created by admin on Fri Dec 15 15:31:52 GMT 2023 , Edited by admin on Fri Dec 15 15:31:52 GMT 2023
PRIMARY
MERCK INDEX
m611
Created by admin on Fri Dec 15 15:31:52 GMT 2023 , Edited by admin on Fri Dec 15 15:31:52 GMT 2023
PRIMARY
PUBCHEM
10097975
Created by admin on Fri Dec 15 15:31:52 GMT 2023 , Edited by admin on Fri Dec 15 15:31:52 GMT 2023
PRIMARY
ECHA (EC/EINECS)
258-703-5
Created by admin on Fri Dec 15 15:31:52 GMT 2023 , Edited by admin on Fri Dec 15 15:31:52 GMT 2023
PRIMARY
CAS
53684-61-0
Created by admin on Fri Dec 15 15:31:52 GMT 2023 , Edited by admin on Fri Dec 15 15:31:52 GMT 2023
PRIMARY
SMS_ID
100000076565
Created by admin on Fri Dec 15 15:31:52 GMT 2023 , Edited by admin on Fri Dec 15 15:31:52 GMT 2023
PRIMARY