PAREPTIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

First approved in 2022

Possibly Marketed Outside US

First approved in 2022

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C14H26N4O3
Molecular Weight	298.3812
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PAREPTIDE

Structure Search

SMILES

CC(C)C[C@@H](N(C)C(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O

InChI

InChIKey=BXCQMQVEMFYKJC-WDEREUQCSA-N

InChI=1S/C14H26N4O3/c1-9(2)7-11(13(20)17-8-12(15)19)18(3)14(21)10-5-4-6-16-10/h9-11,16H,4-8H2,1-3H3,(H2,15,19)(H,17,20)/t10-,11+/m0/s1

HIDE SMILES / InChI

Description
Sources: Elks J., The Dictionary of Drugs: Chemical Data: Chemical Data, Structures, retrieved from:

Pareptide was developed as an antiparkinsonian drug. However, information about the further development of this drug is not available.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Pharmacological activities of the MIF-1 analogues Pro-Leu-Gly, Tyr-Pro-Leu-Gly and pareptide.	1987-11-01	2894644
Pro-Leu-Gly-NH2 and pareptide inhibit development of tolerance to haloperidol catalepsy in the mouse.	1984-09-01	6150468
Determination of the melanotropin-inhibiting factor analogue pareptide in urine by high-performance liquid chromatography.	1981-03-13	6112231
Trace analysis of the MIF analogue pareptide in blood plasma by high-performance liquid chromatography and short-wavelength excitation fluorometry.	1979-08-21	544604

Name

Type

Language

N-(D-1-((CARBAMOYLMETHYL)CARBAMOYL)-3-METHYLBUTYL)-N-METHYL-L-2-PYRROLIDINECARBOXAMIDE

Preferred Name

English

PAREPTIDE

Official Name

English

pareptide [INN]

Common Name

English

GLYCINAMIDE, L-PROLYL-N-METHYL-D-LEUCYL-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C38149

Created by admin on Mon Mar 31 18:19:58 GMT 2025 , Edited by admin on Mon Mar 31 18:19:58 GMT 2025

Code System Code Type Description

INN

4347

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PUBCHEM

10086055

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EVMPD

SUB09623MIG

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ChEMBL

CHEMBL2111011

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DAILYMED

4743XI19RY

Created by admin on Mon Mar 31 18:19:58 GMT 2025 , Edited by admin on Mon Mar 31 18:19:58 GMT 2025

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MESH

C024569

Created by admin on Mon Mar 31 18:19:58 GMT 2025 , Edited by admin on Mon Mar 31 18:19:58 GMT 2025

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FDA UNII

4743XI19RY

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CAS

61484-38-6

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NCI_THESAURUS

C66319

Created by admin on Mon Mar 31 18:19:58 GMT 2025 , Edited by admin on Mon Mar 31 18:19:58 GMT 2025

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EPA CompTox

DTXSID50210450

Created by admin on Mon Mar 31 18:19:58 GMT 2025 , Edited by admin on Mon Mar 31 18:19:58 GMT 2025

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RXCUI

2619909

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SMS_ID

100000082815

Created by admin on Mon Mar 31 18:19:58 GMT 2025 , Edited by admin on Mon Mar 31 18:19:58 GMT 2025

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ACTIVE MOIETY


					4743XI19RY

PAREPTIDE

SALT/SOLVATE (PARENT)


					GC65JE8O95

PAREPTIDE HYDROCHLORIDE

SALT/SOLVATE (PARENT)


					1CMY36S198

PAREPTIDE SULFATE