Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H9N3O2.ClH |
| Molecular Weight | 167.594 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CN(CC(O)=O)C(N)=N
InChI
InChIKey=DGOAYHVIVJYHKU-UHFFFAOYSA-N
InChI=1S/C4H9N3O2.ClH/c1-7(4(5)6)2-3(8)9;/h2H2,1H3,(H3,5,6)(H,8,9);1H
Creatine is an amino acid that occurs in vertebrate tissues and in urine. It is synthesized mainly in the liver from three different amino acids: arginine, glycine, and methionine. In skeletal muscles, which store 95% of it, creatine generally occurs as phosphocreatine. The rest is stored in the brain, heart, and testes. Creatine functions as part of the cell's energy shuttle. It is excreted as creatinine in the urine.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Evolution and physiological roles of phosphagen systems. | 2001 |
|
| Neuroprotective effects of MK-801 on L-2-chloropropionic acid-induced neurotoxicity. | 2001 Feb |
|
| Phosphorylation-dependent alteration in myofilament ca2+ sensitivity but normal mitochondrial function in septic heart. | 2001 Feb |
|
| Parkinsonism and neck extensor myopathy: a new syndrome or coincidental findings? | 2001 Feb |
|
| Thrombectomy with the X-SIZER catheter system in the coronary circulation: initial results from a multi-center study. | 2001 Feb |
|
| Plasma levels of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 are increased in the coronary circulation in patients with acute coronary syndrome. | 2001 Feb |
|
| Tubular cell senescence and expression of TGF-beta1 and p21(WAF1/CIP1) in tubulointerstitial fibrosis of aging rats. | 2001 Feb |
|
| Protection against cellular damage in the rat heart by iodoacetate. | 2001 Feb |
|
| Release of muscle proteins after downhill running in male and female subjects. | 2001 Feb |
|
| Serum concentrations of collagen degrading enzymes and their inhibitors after downhill running. | 2001 Feb |
|
| Uremic concentrations of guanidino compounds inhibit neutrophil superoxide production. | 2001 Feb |
|
| Cardiac troponins and creatine kinase content of striated muscle in common laboratory animals. | 2001 Feb |
|
| Altered activities of rat brain metabolic enzymes caused by pentylenetetrazol kindling and pentylenetetrazol--induced seizures. | 2001 Feb |
|
| Reproducibility of hippocampal single-Voxel proton MR spectroscopy and chemical shift imaging. | 2001 Feb |
|
| Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy. | 2001 Feb |
|
| Emergency department evaluation of chest pain using exercise stress echocardiography. | 2001 Feb |
|
| Benefits of micronised Fenofibrate in type 2 diabetes mellitus subjects with good glycemic control. | 2001 Feb 1 |
|
| Mouse model of myocardial remodelling after ischemia: role of intercellular adhesion molecule-1. | 2001 Feb 1 |
|
| Tumor necrosis factor-alpha (TNF-alpha) plays a protective role in acute viralmyocarditis in mice: A study using mice lacking TNF-alpha. | 2001 Feb 6 |
|
| Use of Doppler ultrasonography to predict the outcome of therapy for renal-artery stenosis. | 2001 Feb 8 |
|
| Deterioration in renal function associated with fibrate therapy. | 2001 Jan |
|
| Treatment of exercise-induced muscle injury via hyperbaric oxygen therapy. | 2001 Jan |
|
| Effect of elbow joint angle on the magnitude of muscle damage to the elbow flexors. | 2001 Jan |
|
| Oxygen free radical generation in healthy blood donors and cardiac patients: the protective effect of allopurinol. | 2001 Jan |
|
| Leukocyte filtration in the early reperfusion phase on cardiopulmonary bypass reduces myocardial injury. | 2001 Jan |
|
| Evidence of axonal damage in the early stages of multiple sclerosis and its relevance to disability. | 2001 Jan |
|
| Improving diagnostic yield in brain biopsy: coupling spectroscopic targeting with real-time needle placement. | 2001 Jan |
|
| Plasma lipids and urinary albumin excretion rate in Type 1 diabetes mellitus: the EURODIAB IDDM Complications Study. | 2001 Jan |
|
| Systemic effects of hyperthermic isolated lower limb perfusion with carboplatin and interferon-beta. | 2001 Jan |
|
| Evaluation of the dystrophin-glycoprotein complex, alpha-actinin, dysferlin and calpain 3 in an autosomal recessive muscular dystrophy in Labrador retrievers. | 2001 Jan |
|
| Mild phenotype of nemaline myopathy with sleep hypoventilation due to a mutation in the skeletal muscle alpha-actin (ACTA1) gene. | 2001 Jan |
|
| Effects of EGF receptor ligands on fetal ovine myoblasts. | 2001 Jan |
|
| Alterations in myocardial creatinine kinase (CK) and lactate dehydrogenase (LDH) isoenzyme-distribution in a model of left ventricular dysfunction. | 2001 Jan |
|
| Myoglobin and creatine kinase isoenzyme MB mass assays: intermethod behaviour of patient sera and commercially available control materials. | 2001 Jan |
|
| Recovery of muscles of old rats after hindlimb immobilisation by external fixation is impaired compared with those of young rats. | 2001 Jan |
|
| Proton MR spectroscopy in patients with acute temporal lobe seizures. | 2001 Jan |
|
| Magnetization transfer imaging and proton MR spectroscopy in the evaluation of axonal injury: correlation with clinical outcome after traumatic brain injury. | 2001 Jan |
|
| Apparent diffusion coefficients in the evaluation of high-grade cerebral gliomas. | 2001 Jan |
|
| Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies. | 2001 Jan 20 |
|
| Expression and purification of polyhistidine-tagged firefly luciferase in insect cells--a potential alternative for process scale-up. | 2001 Jan 23 |
|
| Endogenous synthesis and transport of creatine in the rat brain: an in situ hybridization study. | 2001 Jan 31 |
|
| Myotoxicity studies of injectable biodegradable in-situ forming drug delivery systems. | 2001 Jan 5 |
|
| Visualisation of presence, location, and transmural extent of healed Q-wave and non-Q-wave myocardial infarction. | 2001 Jan 6 |
|
| Use of ergogenic aids by athletes. | 2001 Jan-Feb |
|
| Dysarthria as the leading symptom of hypothyroidism. | 2001 Jan-Feb |
|
| Assessment of coronary reperfusion in patients with myocardial infarction using fatty acid binding protein concentrations in plasma. | 2001 Mar |
|
| IGF-I differentially regulates Bcl-xL and Bax and confers myocardial protection in the rat heart. | 2001 Mar |
|
| An (1)H-MRS evaluation of the phosphocreatine/creatine pool (tCr) in human muscle. | 2001 Mar |
|
| Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans. | 2001 Mar |
|
| Creatine transporter protein content, localization, and gene expression in rat skeletal muscle. | 2001 Mar |
Patents
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Systematic Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
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429W5UKC8E
Created by
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DTXSID50937776
Created by
admin on Sat Dec 16 10:53:47 GMT 2023 , Edited by admin on Sat Dec 16 10:53:47 GMT 2023
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134732
Created by
admin on Sat Dec 16 10:53:47 GMT 2023 , Edited by admin on Sat Dec 16 10:53:47 GMT 2023
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17050-09-8
Created by
admin on Sat Dec 16 10:53:47 GMT 2023 , Edited by admin on Sat Dec 16 10:53:47 GMT 2023
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PRIMARY |
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD
