Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H9N3O2.ClH |
| Molecular Weight | 167.594 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CN(CC(O)=O)C(N)=N
InChI
InChIKey=DGOAYHVIVJYHKU-UHFFFAOYSA-N
InChI=1S/C4H9N3O2.ClH/c1-7(4(5)6)2-3(8)9;/h2H2,1H3,(H3,5,6)(H,8,9);1H
| Molecular Formula | C4H9N3O2 |
| Molecular Weight | 131.1332 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Creatine is an amino acid that occurs in vertebrate tissues and in urine. It is synthesized mainly in the liver from three different amino acids: arginine, glycine, and methionine. In skeletal muscles, which store 95% of it, creatine generally occurs as phosphocreatine. The rest is stored in the brain, heart, and testes. Creatine functions as part of the cell's energy shuttle. It is excreted as creatinine in the urine.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder. | 2001 Apr |
|
| Neuroprotective effects of MK-801 on L-2-chloropropionic acid-induced neurotoxicity. | 2001 Feb |
|
| Phosphorylation-dependent alteration in myofilament ca2+ sensitivity but normal mitochondrial function in septic heart. | 2001 Feb |
|
| Tubular cell senescence and expression of TGF-beta1 and p21(WAF1/CIP1) in tubulointerstitial fibrosis of aging rats. | 2001 Feb |
|
| Protection against cellular damage in the rat heart by iodoacetate. | 2001 Feb |
|
| Release of muscle proteins after downhill running in male and female subjects. | 2001 Feb |
|
| Serum concentrations of collagen degrading enzymes and their inhibitors after downhill running. | 2001 Feb |
|
| Uremic concentrations of guanidino compounds inhibit neutrophil superoxide production. | 2001 Feb |
|
| Altered activities of rat brain metabolic enzymes caused by pentylenetetrazol kindling and pentylenetetrazol--induced seizures. | 2001 Feb |
|
| Reproducibility of hippocampal single-Voxel proton MR spectroscopy and chemical shift imaging. | 2001 Feb |
|
| Inhibition of p38 MAPK alpha/beta reduces ischemic injury and does not block protective effects of preconditioning. | 2001 Feb |
|
| Posttransplantation relapse of FSGS is characterized by glomerular epithelial cell transdifferentiation. | 2001 Feb |
|
| Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy. | 2001 Feb |
|
| Emergency department evaluation of chest pain using exercise stress echocardiography. | 2001 Feb |
|
| Safe discharge from the cardiac emergency room with a rapid rule-out myocardial infarction protocol using serial CK-MB(mass). | 2001 Feb |
|
| Sensitivity of quantitative (1)H magnetic resonance spectroscopy of the brain in detecting early neuronal damage in systemic lupus erythematosus. | 2001 Feb |
|
| Mouse model of myocardial remodelling after ischemia: role of intercellular adhesion molecule-1. | 2001 Feb 1 |
|
| Structure of an intermediate in the unfolding of creatine kinase. | 2001 Feb 1 |
|
| Tumor necrosis factor-alpha (TNF-alpha) plays a protective role in acute viralmyocarditis in mice: A study using mice lacking TNF-alpha. | 2001 Feb 6 |
|
| Deterioration in renal function associated with fibrate therapy. | 2001 Jan |
|
| Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin. | 2001 Jan |
|
| Exercise training increases creatine kinase capacity in canine myocardium. | 2001 Jan |
|
| Improving diagnostic yield in brain biopsy: coupling spectroscopic targeting with real-time needle placement. | 2001 Jan |
|
| Plasma lipids and urinary albumin excretion rate in Type 1 diabetes mellitus: the EURODIAB IDDM Complications Study. | 2001 Jan |
|
| Systemic effects of hyperthermic isolated lower limb perfusion with carboplatin and interferon-beta. | 2001 Jan |
|
| Pretreatment of human myocardium with adenosine. | 2001 Jan |
|
| Myoglobin and creatine kinase isoenzyme MB mass assays: intermethod behaviour of patient sera and commercially available control materials. | 2001 Jan |
|
| Proton MR spectroscopy in patients with acute temporal lobe seizures. | 2001 Jan |
|
| Regional differences and metabolic changes in normal aging of the human brain: proton MR spectroscopic imaging study. | 2001 Jan |
|
| Transient QT interval prolongation with inverted T waves indicates myocardial salvage on dual radionuclide single-photon emission computed tomography in acute anterior myocardial infarction. | 2001 Jan |
|
| Impact of right ventricular involvement on mortality and morbidity in patients with inferior myocardial infarction. | 2001 Jan |
|
| Q-wave evolution of a first acute myocardial infarction without significant ST segment elevation. | 2001 Jan |
|
| Effect of oral creatine supplementation on human muscle GLUT4 protein content after immobilization. | 2001 Jan |
|
| Role of exercise and ascorbate on plasma antioxidant capacity in thoroughbred race horses. | 2001 Jan |
|
| Creatine supplementation increases renal disease progression in Han:SPRD-cy rats. | 2001 Jan |
|
| Protein kinase C isoform-dependent myocardial protection by ischemic preconditioning and potassium cardioplegia. | 2001 Jan |
|
| Prenatal programming of adult hypertension in the rat. | 2001 Jan |
|
| Validity of NIR spectroscopy for quantitatively measuring muscle oxidative metabolic rate in exercise. | 2001 Jan |
|
| Magnetic resonance imaging and spectroscopic changes in brains of patients with cerebrotendinous xanthomatosis. | 2001 Jan |
|
| Supplemental creatine may decrease serum homocysteine and abolish the homocysteine 'gender gap' by suppressing endogenous creatine synthesis. | 2001 Jan |
|
| Tissue engineering of functional cardiac muscle: molecular, structural, and electrophysiological studies. | 2001 Jan |
|
| Varicella myocarditis in an adult. | 2001 Jan |
|
| Axonal damage in multiple sclerosis plaques: a combined magnetic resonance imaging and 1H-magnetic resonance spectroscopy study. | 2001 Jan 1 |
|
| Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies. | 2001 Jan 20 |
|
| Visualisation of presence, location, and transmural extent of healed Q-wave and non-Q-wave myocardial infarction. | 2001 Jan 6 |
|
| Use of ergogenic aids by athletes. | 2001 Jan-Feb |
|
| Assessment of coronary reperfusion in patients with myocardial infarction using fatty acid binding protein concentrations in plasma. | 2001 Mar |
|
| IGF-I differentially regulates Bcl-xL and Bax and confers myocardial protection in the rat heart. | 2001 Mar |
|
| An (1)H-MRS evaluation of the phosphocreatine/creatine pool (tCr) in human muscle. | 2001 Mar |
|
| Creatine transporter protein content, localization, and gene expression in rat skeletal muscle. | 2001 Mar |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 10:53:46 GMT 2023
by
admin
on
Sat Dec 16 10:53:46 GMT 2023
|
| Record UNII |
429W5UKC8E
|
| Record Status |
Validated (UNII)
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| Record Version |
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429W5UKC8E
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DTXSID50937776
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134732
Created by
admin on Sat Dec 16 10:53:47 GMT 2023 , Edited by admin on Sat Dec 16 10:53:47 GMT 2023
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17050-09-8
Created by
admin on Sat Dec 16 10:53:47 GMT 2023 , Edited by admin on Sat Dec 16 10:53:47 GMT 2023
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> SALT/SOLVATE |
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