Details
Stereochemistry | ACHIRAL |
Molecular Formula | C4H9N3O2.ClH |
Molecular Weight | 167.594 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CN(CC(O)=O)C(N)=N
InChI
InChIKey=DGOAYHVIVJYHKU-UHFFFAOYSA-N
InChI=1S/C4H9N3O2.ClH/c1-7(4(5)6)2-3(8)9;/h2H2,1H3,(H3,5,6)(H,8,9);1H
Molecular Formula | C4H9N3O2 |
Molecular Weight | 131.1332 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Creatine is an amino acid that occurs in vertebrate tissues and in urine. It is synthesized mainly in the liver from three different amino acids: arginine, glycine, and methionine. In skeletal muscles, which store 95% of it, creatine generally occurs as phosphocreatine. The rest is stored in the brain, heart, and testes. Creatine functions as part of the cell's energy shuttle. It is excreted as creatinine in the urine.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Evolution and physiological roles of phosphagen systems. | 2001 |
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Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder. | 2001 Apr |
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Neuroprotective effects of MK-801 on L-2-chloropropionic acid-induced neurotoxicity. | 2001 Feb |
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Phosphorylation-dependent alteration in myofilament ca2+ sensitivity but normal mitochondrial function in septic heart. | 2001 Feb |
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Parkinsonism and neck extensor myopathy: a new syndrome or coincidental findings? | 2001 Feb |
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Thrombectomy with the X-SIZER catheter system in the coronary circulation: initial results from a multi-center study. | 2001 Feb |
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Plasma levels of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 are increased in the coronary circulation in patients with acute coronary syndrome. | 2001 Feb |
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A controlled trial of topical nitroglycerin in a New Zealand white rabbit model of brown recluse spider envenomation. | 2001 Feb |
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The three-dimensional structure of cytosolic bovine retinal creatine kinase. | 2001 Feb |
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Reproducibility of hippocampal single-Voxel proton MR spectroscopy and chemical shift imaging. | 2001 Feb |
|
Inhibition of p38 MAPK alpha/beta reduces ischemic injury and does not block protective effects of preconditioning. | 2001 Feb |
|
Myopathic form of very-long chain acyl-coa dehydrogenase deficiency: evidence for temperature-sensitive mild mutations in both mutant alleles in a Japanese girl. | 2001 Feb |
|
Safe discharge from the cardiac emergency room with a rapid rule-out myocardial infarction protocol using serial CK-MB(mass). | 2001 Feb |
|
Sensitivity of quantitative (1)H magnetic resonance spectroscopy of the brain in detecting early neuronal damage in systemic lupus erythematosus. | 2001 Feb |
|
Structure of an intermediate in the unfolding of creatine kinase. | 2001 Feb 1 |
|
Use of Doppler ultrasonography to predict the outcome of therapy for renal-artery stenosis. | 2001 Feb 8 |
|
Deterioration in renal function associated with fibrate therapy. | 2001 Jan |
|
Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin. | 2001 Jan |
|
Exercise training increases creatine kinase capacity in canine myocardium. | 2001 Jan |
|
Creatine supplementation affects muscle creatine during energy restriction. | 2001 Jan |
|
Treatment of exercise-induced muscle injury via hyperbaric oxygen therapy. | 2001 Jan |
|
Effect of elbow joint angle on the magnitude of muscle damage to the elbow flexors. | 2001 Jan |
|
Oxygen free radical generation in healthy blood donors and cardiac patients: the protective effect of allopurinol. | 2001 Jan |
|
Leukocyte filtration in the early reperfusion phase on cardiopulmonary bypass reduces myocardial injury. | 2001 Jan |
|
Evidence of axonal damage in the early stages of multiple sclerosis and its relevance to disability. | 2001 Jan |
|
Clinical, electrocardiographic, and biochemical data for immediate risk stratification in acute coronary syndromes. | 2001 Jan |
|
Plasma lipids and urinary albumin excretion rate in Type 1 diabetes mellitus: the EURODIAB IDDM Complications Study. | 2001 Jan |
|
Effects of EGF receptor ligands on fetal ovine myoblasts. | 2001 Jan |
|
Pretreatment of human myocardium with adenosine. | 2001 Jan |
|
Validation of NACB and IFCC guidelines for the use of cardiac markers for early diagnosis and risk assessment in patients with acute coronary syndromes. | 2001 Jan |
|
Myoglobin and creatine kinase isoenzyme MB mass assays: intermethod behaviour of patient sera and commercially available control materials. | 2001 Jan |
|
Regional differences and metabolic changes in normal aging of the human brain: proton MR spectroscopic imaging study. | 2001 Jan |
|
Type 2 iodothyronin deiodinase transgene expression in the mouse heart causes cardiac-specific thyrotoxicosis. | 2001 Jan |
|
Role of exercise and ascorbate on plasma antioxidant capacity in thoroughbred race horses. | 2001 Jan |
|
Win, place, show: creatine consumption and the price of winning. | 2001 Jan |
|
Ischemic preconditioning with opening of mitochondrial adenosine triphosphate-sensitive potassium channels or Na/H exchange inhibition: which is the best protective strategy for heart transplants? | 2001 Jan |
|
Protein kinase C isoform-dependent myocardial protection by ischemic preconditioning and potassium cardioplegia. | 2001 Jan |
|
Varicella myocarditis in an adult. | 2001 Jan |
|
A genome scan for renal function among hypertensives: the HyperGEN study. | 2001 Jan |
|
Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies. | 2001 Jan 20 |
|
Expression and purification of polyhistidine-tagged firefly luciferase in insect cells--a potential alternative for process scale-up. | 2001 Jan 23 |
|
Myotoxicity studies of injectable biodegradable in-situ forming drug delivery systems. | 2001 Jan 5 |
|
Visualisation of presence, location, and transmural extent of healed Q-wave and non-Q-wave myocardial infarction. | 2001 Jan 6 |
|
Use of ergogenic aids by athletes. | 2001 Jan-Feb |
|
Dysarthria as the leading symptom of hypothyroidism. | 2001 Jan-Feb |
|
Assessment of coronary reperfusion in patients with myocardial infarction using fatty acid binding protein concentrations in plasma. | 2001 Mar |
|
IGF-I differentially regulates Bcl-xL and Bax and confers myocardial protection in the rat heart. | 2001 Mar |
|
Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans. | 2001 Mar |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:30:06 GMT 2025
by
admin
on
Mon Mar 31 23:30:06 GMT 2025
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Record UNII |
429W5UKC8E
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Record Status |
Validated (UNII)
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Record Version |
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429W5UKC8E
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DTXSID50937776
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134732
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17050-09-8
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PARENT -> SALT/SOLVATE |
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